{"title":"COMPARISION OF PERIOPERATIVE SERUM LACTATE LEVEL IN ON-PUMP VERSUS OFF-PUMP CORONARY ARTERY BYPASS GRAFT","authors":"Hymavathi Varla, Rahul Nethikar, Vijaya Mohan Canjeevaram","doi":"10.36106/gjra/8400336","DOIUrl":null,"url":null,"abstract":"Coronary artery bypass grafting (CABG) can be performed with the use of cardiopulmonary bypass (onpump CABG) or without (off-pump CABG). Lactate is used as a marker for oxygen deciency in anaerobic\nmetabolism at the tissue level. Increase in tissue lactate concentration is associated with cellular dysfunction due to the\ndepletion of high energy phosphate compounds. This Institution based Retrospective study was done to Compare the peri -\noperative serum lactate levels in patients undergoing On-pump versus Off-pump CABG Surgery. Total 20 patients were\nanalysed with mean age of 56.35 +- 4.33 years. EURO score-2 shows 0.85 +- 0.28 and 1.21 +- 0.54 in On-pump and Off-pump\nrespectively. EURO score-2 is high in Off-pump when compared with On-pump and this ndings are statistically not signicant\n(p: 0.07). Peak lactate levels in On-pump& Off-pump CABG are 4.7& 5.8 mmol/dl respectively. Older studies showed that there\nwas a signicant association seen between lactate level and CPB. Off-pump surgery may improve short-term outcomes such as\nrenal failure and stroke. In our study, there were no signicant differences in postoperative patterns of release of Lactates in\npatients with On-pump v/s Off-pump","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"4 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global journal for research analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/gjra/8400336","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Coronary artery bypass grafting (CABG) can be performed with the use of cardiopulmonary bypass (onpump CABG) or without (off-pump CABG). Lactate is used as a marker for oxygen deciency in anaerobic
metabolism at the tissue level. Increase in tissue lactate concentration is associated with cellular dysfunction due to the
depletion of high energy phosphate compounds. This Institution based Retrospective study was done to Compare the peri -
operative serum lactate levels in patients undergoing On-pump versus Off-pump CABG Surgery. Total 20 patients were
analysed with mean age of 56.35 +- 4.33 years. EURO score-2 shows 0.85 +- 0.28 and 1.21 +- 0.54 in On-pump and Off-pump
respectively. EURO score-2 is high in Off-pump when compared with On-pump and this ndings are statistically not signicant
(p: 0.07). Peak lactate levels in On-pump& Off-pump CABG are 4.7& 5.8 mmol/dl respectively. Older studies showed that there
was a signicant association seen between lactate level and CPB. Off-pump surgery may improve short-term outcomes such as
renal failure and stroke. In our study, there were no signicant differences in postoperative patterns of release of Lactates in
patients with On-pump v/s Off-pump