The Polk COVID-19 and Flu Response clinical trial: COVID-19 antibody positivity higher in Black EMS workers

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Abstract

This study reports on a countywide assessment of COVID-19 positivity among emergency medical services workers. Participants completed a short survey of demographic factors and co-morbidities prior to obtaining COVID-19 and influenza testing to analyze the prevalence of these two respiratory viruses that EMS workers, being the first on the scene, are at special risk for, especially in the early days of the pandemic. A total of 7% had a positive COVID-19 antibody test. Although Black EMS personnel only comprised 9% of the cohort, they were significantly more likely to test positive for COVID-19 (P=0.0012). Black race remained a statistically significant predictor in a multivariate model that included the age, sex, BMI, number of hours of direct patient contact, whether the medic was symptomatic, presence of co-morbidities and whether or not the medic had received a flu shot prior (P=0.0008, 95% CI 0.0621-0.2354). This clinical trial (NCT04682132) ) was registered at clinicaltrials.gov, a resource provided by the U.S. National Library of Medicine.
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波尔克 COVID-19 和流感反应临床试验:黑人急救人员的 COVID-19 抗体阳性率较高
本研究报告了对全县范围内急救医疗服务人员 COVID-19 阳性率的评估。参加者在接受 COVID-19 和流感检测前完成了一项关于人口统计因素和并发症的简短调查,以分析这两种呼吸道病毒的流行情况。共有 7% 的人 COVID-19 抗体检测呈阳性。虽然黑人急救人员只占总数的 9%,但他们的 COVID-19 抗体检测呈阳性的几率明显更高(P=0.0012)。在一个包括年龄、性别、体重指数、直接接触病人的小时数、医护人员是否有症状、是否有并发症以及医护人员之前是否注射过流感疫苗的多变量模型中,黑人仍然是一个具有统计学意义的预测因素(P=0.0008,95% CI 0.0621-0.2354)。该临床试验(NCT04682132)已在美国国家医学图书馆提供的资源 clinicaltrials.gov 上注册。
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