Case of sickle cell disease with manifestations of severe vitamin D deficiency: A case report

Abstract

Calcium homeostasis and appropriate calcium absorption depend on adequate levels of vitamin D. Vitamin D deficiency manifests as osteomalacia, rickets, and bone deformities involving the spine and other bones. Patients with sickle cell disease (SCD) are more likely to experience vitamin D deficiencies. In this case, we describe a 23-year-old male case with of sickle cell anemia with signs of severe vitamin D deficiency and complications of SCD. This case report emphasizes the importance of considering long-term vitamin D supplementation from an early age in individuals with SCD.