Stretchable Fractal Electrodes Integrated on Miniature Semi-Expanded Microballoon Catheter for Directional Nerve Stimulation

Xiaoli You, Fanqi Sun, Kai Xue, Xianxia Yan, Le Zhou, Minghao Wang, Zekai Liang, Kai Tao, Honglong Chang, Bowen Ji
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Abstract

In recent years, the percutaneous balloon compression (PBC) does not require craniotomy and has gradually become the preferred treatment for trigeminal neuralgia. However, there is a lack of microballoon catheters with real-time feedback capability to replace the current personal experience from X-ray pictures. This paper reports a stretchable fractal electrode array integrated on miniature semi-expanded microballoon catheter for the first time, which can accommodate large expansion. Six electrode sites are uniformly distributed in 120° circumferential direction on two ends of the microballon. Thus, the fractal electrodes can apply directional electrical stimulation with good spatial resolution to the compressed ganglion during the microballoon expansion, along with the evoked myoelectric potential to improve treatment of trigeminal neuralgia. Optimized fractal interconnects can integrate to the semi-expanded balloon with sufficient stretchability. Besides, the electrode sites with ring ground are assembled on metal marker rings without deformation for better nerve stimulation.
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集成在微型半膨胀微球导管上的可伸缩分形电极用于定向神经刺激
近年来,无需开颅手术的经皮球囊压迫术(PBC)逐渐成为治疗三叉神经痛的首选方法。然而,目前还缺乏具有实时反馈能力的微球囊导管,以取代目前通过 X 光照片获得的个人经验。本文首次报道了一种集成在微型半膨胀微球导管上的可伸缩分形电极阵列,它可以适应较大的膨胀。六个电极点以 120° 的圆周方向均匀分布在微球的两端。因此,在微球扩张过程中,分形电极能以良好的空间分辨率对受压神经节进行定向电刺激,同时诱发肌电动势,从而改善三叉神经痛的治疗。经过优化的分形互连可以集成到具有足够伸展性的半膨胀球囊中。此外,带有环形接地的电极点装配在金属标记环上,不会发生变形,从而能更好地刺激神经。
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