{"title":"Peptides conjugation on biomaterials: chemical conjugation approaches and their promoted multifunction for biomedical applications","authors":"","doi":"10.1007/s12257-024-00095-5","DOIUrl":null,"url":null,"abstract":"<h3>Abstract</h3> <p>Researchers have made significant efforts to attach peptides to various biomaterials, resulting in diverse functionalities. By harnessing the advantages of peptides, functions such as high specificity, potency, cost-effectiveness, small size for improved tissue penetration and targeted delivery, biodegradability, and novel therapeutic applications can be achieved through their attachment to biomaterials. Of various methods available for modifying biomolecules, chemical techniques are the most established and can effectively immobilize the desired molecule onto a specific surface. This article provides a comprehensive overview of the chemical modification methods used for attaching peptides to various biomaterials in recent studies and showcases some of their latest applications.</p>","PeriodicalId":8936,"journal":{"name":"Biotechnology and Bioprocess Engineering","volume":"226 1","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotechnology and Bioprocess Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s12257-024-00095-5","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Researchers have made significant efforts to attach peptides to various biomaterials, resulting in diverse functionalities. By harnessing the advantages of peptides, functions such as high specificity, potency, cost-effectiveness, small size for improved tissue penetration and targeted delivery, biodegradability, and novel therapeutic applications can be achieved through their attachment to biomaterials. Of various methods available for modifying biomolecules, chemical techniques are the most established and can effectively immobilize the desired molecule onto a specific surface. This article provides a comprehensive overview of the chemical modification methods used for attaching peptides to various biomaterials in recent studies and showcases some of their latest applications.
期刊介绍：
Biotechnology and Bioprocess Engineering is an international bimonthly journal published by the Korean Society for Biotechnology and Bioengineering. BBE is devoted to the advancement in science and technology in the wide area of biotechnology, bioengineering, and (bio)medical engineering. This includes but is not limited to applied molecular and cell biology, engineered biocatalysis and biotransformation, metabolic engineering and systems biology, bioseparation and bioprocess engineering, cell culture technology, environmental and food biotechnology, pharmaceutics and biopharmaceutics, biomaterials engineering, nanobiotechnology, and biosensor and bioelectronics.
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