Use of natural language processing method to identify regional anesthesia from clinical notes

Laura A Graham, Samantha S Illarmo, Sherry M Wren, Michelle C Odden, Seshadri C Mudumbai
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Abstract

Introduction Accurate data capture is integral for research and quality improvement efforts. Unfortunately, limited guidance for defining and documenting regional anesthesia has resulted in wide variation in documentation practices, even within individual hospitals, which can lead to missing and inaccurate data. This cross-sectional study sought to evaluate the performance of a natural language processing (NLP)-based algorithm developed to identify regional anesthesia within unstructured clinical notes. Methods We obtained postoperative clinical notes for all patients undergoing elective non-cardiac surgery with general anesthesia at one of six Veterans Health Administration hospitals in California between January 1, 2017, and December 31, 2022. After developing and executing our algorithm, we compared our results to a frequently used referent, the Corporate Data Warehouse structured data, to assess the completeness and accuracy of the currently available data. Measures of agreement included sensitivity, positive predictive value, false negative rate, and accuracy. Results We identified 27,713 procedures, of which 9310 (33.6%) received regional anesthesia. 96.6% of all referent regional anesthesia cases were identified in the clinic notes with a very low false negative rate and good accuracy (false negative rate=0.8%, accuracy=82.5%). Surprisingly, the clinic notes documented more than two times the number of regional anesthesia cases that were documented in the referent (algorithm n=9154 vs referent n=4606). Discussion While our algorithm identified nearly all regional anesthesia cases from the referent, it also identified more than two times as many regional anesthesia cases as the referent, raising concerns about the accuracy and completeness of regional anesthesia documentation in administrative and clinical databases. We found that NLP was a promising alternative for identifying clinical information when existing databases lack complete documentation.
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使用自然语言处理方法从临床笔记中识别区域麻醉
导言 准确的数据采集是研究和质量改进工作不可或缺的一部分。遗憾的是,由于区域麻醉的定义和记录指南有限,导致即使是在单个医院内,记录方法也存在很大差异,这可能会导致数据缺失和不准确。本横断面研究旨在评估一种基于自然语言处理 (NLP) 的算法的性能,该算法可在非结构化临床笔记中识别区域麻醉。方法 我们获取了 2017 年 1 月 1 日至 2022 年 12 月 31 日期间在加利福尼亚州六家退伍军人健康管理局医院之一接受选择性非心脏手术并进行全身麻醉的所有患者的术后临床笔记。在开发并执行算法后,我们将结果与常用的参考数据(企业数据仓库结构化数据)进行了比较,以评估当前可用数据的完整性和准确性。衡量一致性的指标包括灵敏度、阳性预测值、假阴性率和准确性。结果 我们确定了 27713 例手术,其中 9310 例(33.6%)接受了区域麻醉。96.6%的区域麻醉参考病例在门诊病历中得到了确认,假阴性率极低,准确率很高(假阴性率=0.8%,准确率=82.5%)。令人惊讶的是,临床笔记中记录的区域麻醉病例数是参考病例数的两倍多(算法 n=9154 vs 参考病例 n=4606)。讨论 虽然我们的算法识别出了参考文献中几乎所有的区域麻醉病例,但它识别出的区域麻醉病例数量也是参考文献的两倍多,这引起了人们对行政和临床数据库中区域麻醉记录的准确性和完整性的关注。我们发现,在现有数据库缺乏完整文档的情况下,NLP 是识别临床信息的一种很有前途的替代方法。
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