首页 > 最新文献

Regional Anesthesia & Pain Medicine最新文献

英文 中文
Optimal techniques of ultrasound-guided superficial and deep parasternal intercostal plane blocks—a cadaveric study 超声引导下浅层和深层胸骨旁肋间平面阻滞的最佳技术--尸体研究
Pub Date : 2024-09-16 DOI: 10.1136/rapm-2024-105962
Burhan Dost, Serkan Tulgar, Ali Ahiskalioglu, Alessandro De Cassai
We would like to extend our congratulations to Samerchua et al [1][1] for their valuable contribution to the literature with their cadaveric study exploring the optimal techniques for parasternal blocks. This study presents significant findings that enhance our understanding of the efficacy and
Samerchua 等人[1][1] 通过尸体研究探讨了胸骨旁阻滞的最佳技术,为文献做出了宝贵贡献,在此我们向他们表示祝贺。这项研究提供了重要的发现,加深了我们对胸骨旁阻滞的疗效和安全性的理解。
{"title":"Optimal techniques of ultrasound-guided superficial and deep parasternal intercostal plane blocks—a cadaveric study","authors":"Burhan Dost, Serkan Tulgar, Ali Ahiskalioglu, Alessandro De Cassai","doi":"10.1136/rapm-2024-105962","DOIUrl":"https://doi.org/10.1136/rapm-2024-105962","url":null,"abstract":"We would like to extend our congratulations to Samerchua et al [1][1] for their valuable contribution to the literature with their cadaveric study exploring the optimal techniques for parasternal blocks. This study presents significant findings that enhance our understanding of the efficacy and","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invited reply letter: optimal techniques of ultrasound-guided superficial and deep parasternal intercostal plane blocks – a cadaveric study 特邀回信:超声引导下浅层和深层胸骨旁肋间平面阻滞的最佳技术--一项尸体研究
Pub Date : 2024-09-16 DOI: 10.1136/rapm-2024-106012
Artid Samerchua, Prangmalee Leurcharusmee, Kittitorn Supphapipat, Pasuk Mahakkanukrauh
We extend our sincere gratitude to Dost et al for their keen interest in our recent cadaveric study, which investigates the optimal techniques for ultrasound-guided parasternal intercostal plane (PIP) blocks.[1 2][1] Our findings indicate that using a total volume of 20 mL of dye, with triple
我们衷心感谢 Dost 等人对我们最近的尸体研究的浓厚兴趣,该研究探讨了超声引导下胸骨旁肋间平面 (PIP) 阻滞的最佳技术。
{"title":"Invited reply letter: optimal techniques of ultrasound-guided superficial and deep parasternal intercostal plane blocks – a cadaveric study","authors":"Artid Samerchua, Prangmalee Leurcharusmee, Kittitorn Supphapipat, Pasuk Mahakkanukrauh","doi":"10.1136/rapm-2024-106012","DOIUrl":"https://doi.org/10.1136/rapm-2024-106012","url":null,"abstract":"We extend our sincere gratitude to Dost et al for their keen interest in our recent cadaveric study, which investigates the optimal techniques for ultrasound-guided parasternal intercostal plane (PIP) blocks.[1 2][1] Our findings indicate that using a total volume of 20 mL of dye, with triple","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal analgesia and the erector spinae plane block in a rapid recovery pathway after posterior spinal fusion in adolescent idiopathic scoliosis: a randomized controlled study of practicality 青少年特发性脊柱侧凸后路脊柱融合术后快速恢复路径中的多模式镇痛和竖脊肌平面阻滞:实用性随机对照研究
Pub Date : 2024-09-16 DOI: 10.1136/rapm-2024-105748
Jordan Ruby, Marko Popovic, Alex Illescas, Pamela Wendel, Michelle Carley, Roger F Widmann, John S Blanco, Kathryn DelPizzo, Ellen M Soffin
Adolescent idiopathic scoliosis (AIS) affects 1%–3% of patients aged 10–16, with some requiring posterior spinal fusion (PSF).[1][1] While multimodal analgesics are standard for managing acute postoperative pain in these patients having PSF, the application of advanced regional anesthetic
青少年特发性脊柱侧凸(AIS)影响着1%-3%的10-16岁患者,其中一些患者需要进行后路脊柱融合术(PSF)。
{"title":"Multimodal analgesia and the erector spinae plane block in a rapid recovery pathway after posterior spinal fusion in adolescent idiopathic scoliosis: a randomized controlled study of practicality","authors":"Jordan Ruby, Marko Popovic, Alex Illescas, Pamela Wendel, Michelle Carley, Roger F Widmann, John S Blanco, Kathryn DelPizzo, Ellen M Soffin","doi":"10.1136/rapm-2024-105748","DOIUrl":"https://doi.org/10.1136/rapm-2024-105748","url":null,"abstract":"Adolescent idiopathic scoliosis (AIS) affects 1%–3% of patients aged 10–16, with some requiring posterior spinal fusion (PSF).[1][1] While multimodal analgesics are standard for managing acute postoperative pain in these patients having PSF, the application of advanced regional anesthetic","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In reply: evaluating the efficacy of PENG and SIFICB in hip fracture analgesia – a critical analysis 回复:评估 PENG 和 SIFICB 在髋部骨折镇痛中的疗效--批判性分析
Pub Date : 2024-09-16 DOI: 10.1136/rapm-2024-106017
Won Uk Koh, Hyungtae Kim, Yeon Ju Kim, Ji In Park, Hyun-Jin Yeo, Youngjin Ro, Ha-Jung Kim
We have read Julio Orrego et al ’s letter[1][1] and are grateful for their interest and feedback on our article.[2][2] They highlighted a potential misinterpretation of our study results, particularly regarding the absence of a statistically significant difference in analgesic effects between the
我们阅读了 Julio Orrego 等人的来信[1][1],感谢他们对我们文章的关注和反馈意见[2][2]。他们强调了对我们研究结果的潜在误读,尤其是在镇痛效果方面,两种药物之间没有统计学意义上的显著差异。
{"title":"In reply: evaluating the efficacy of PENG and SIFICB in hip fracture analgesia – a critical analysis","authors":"Won Uk Koh, Hyungtae Kim, Yeon Ju Kim, Ji In Park, Hyun-Jin Yeo, Youngjin Ro, Ha-Jung Kim","doi":"10.1136/rapm-2024-106017","DOIUrl":"https://doi.org/10.1136/rapm-2024-106017","url":null,"abstract":"We have read Julio Orrego et al ’s letter[1][1] and are grateful for their interest and feedback on our article.[2][2] They highlighted a potential misinterpretation of our study results, particularly regarding the absence of a statistically significant difference in analgesic effects between the","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the need for accuracy and consistency in cadaveric studies between technique and imaging: are we missing “bull’s eye”? 尸体研究需要技术和成像之间的准确性和一致性:我们是否错过了 "靶心"?
Pub Date : 2024-09-11 DOI: 10.1136/rapm-2024-105934
Mauricio Forero, Alvaro Diaz Rodriguez, Rami Adel Kamel
We have read with interest the article by Luchsinger et al ,[1][1] investigating the spread of 20 mL of injectate after the performance of an erector spinae plane block (ESPB) at the T9 level in cadavers. Lingering doubts need to be clarified. The study concludes that the ventral rami were not
我们饶有兴趣地阅读了 Luchsinger 等人的文章,[1][1] 研究了在尸体 T9 水平进行竖脊肌平面阻滞(ESPB)后 20 毫升注射液的扩散情况。尚存在的疑问有待澄清。该研究得出结论,腹侧韧带并没有
{"title":"On the need for accuracy and consistency in cadaveric studies between technique and imaging: are we missing “bull’s eye”?","authors":"Mauricio Forero, Alvaro Diaz Rodriguez, Rami Adel Kamel","doi":"10.1136/rapm-2024-105934","DOIUrl":"https://doi.org/10.1136/rapm-2024-105934","url":null,"abstract":"We have read with interest the article by Luchsinger et al ,[1][1] investigating the spread of 20 mL of injectate after the performance of an erector spinae plane block (ESPB) at the T9 level in cadavers. Lingering doubts need to be clarified. The study concludes that the ventral rami were not","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for persistent postoperative opioid use: an entity distinct from chronic postsurgical pain 术后持续使用阿片类药物的风险因素:有别于慢性术后疼痛的一个实体
Pub Date : 2024-09-11 DOI: 10.1136/rapm-2024-105599
Sama Ramo, Stephan Frangakis, Jennifer F Waljee, Mark C Bicket
Despite a decline in opioid prescriptions over the past decade, patients commonly receive opioid analgesics as a treatment for postoperative pain in the USA. One complication that patients may experience after surgery is persistent postoperative opioid use (PPOU), or opioid use beyond the typical recovery period. Often defined as beyond 3 months postsurgery, PPOU is frequently conflated with chronic postsurgical pain (CPSP), where pain persists well after the expected healing time following surgery. This narrative review explores the distinct risk factors for each condition, their interrelation, and potential future research directions. For PPOU, major risk factors include the risky use of substances including misuse and use disorders; depression and other mental health disorders; a history of chronic pain before surgery including back pain; and certain surgical types (ie, total knee arthropathy, open cholecystectomy, total hip arthropathy). Conversely, CPSP risk factors include the type of surgery (ie, thoracic and breast surgeries), mental health conditions (particularly catastrophizing), and pain in both the preoperative and postoperative phases. Despite the overlap of some factors, studies typically employ different frameworks when examining PPOU and CPSP, with a biopsychosocial model applied for CPSP and little emphasis on an individual’s social environment employed for PPOU. Additionally, existing studies predominantly rely on retrospective insurance claims data, which may not capture the full scope of risk factors. To fill gaps in understanding, investigations may prospectively assess and analyze patient-reported outcomes, implement similar frameworks, and concurrently measure both conditions to advance the scientific understanding of PPOU and CPSP. No data are available.
尽管阿片类药物的处方量在过去十年中有所下降,但在美国,患者通常还是会接受阿片类镇痛药来治疗术后疼痛。患者术后可能出现的一种并发症是术后阿片类药物的持续使用(PPOU),或者说阿片类药物的使用超过了典型的恢复期。PPOU 通常被定义为术后 3 个月以上,经常与慢性术后疼痛(CPSP)相混淆,后者是指术后疼痛在预期愈合时间后仍持续存在。这篇叙述性综述探讨了每种情况的不同风险因素、它们之间的相互关系以及未来潜在的研究方向。就 PPOU 而言,主要风险因素包括药物的危险使用,包括滥用和使用障碍;抑郁症和其他精神疾病;手术前的慢性疼痛史,包括背痛;以及某些手术类型(即全膝关节病、开放性胆囊切除术、全髋关节病)。相反,CPSP 风险因素包括手术类型(即胸部和乳房手术)、精神健康状况(尤其是灾难化)以及术前和术后疼痛。尽管某些因素存在重叠,但在研究 PPOU 和 CPSP 时,研究通常采用不同的框架,CPSP 采用生物心理社会模型,而 PPOU 很少强调个人的社会环境。此外,现有研究主要依赖于回顾性保险理赔数据,这可能无法捕捉到全部风险因素。为了填补认识上的空白,调查可以对患者报告的结果进行前瞻性评估和分析,实施类似的框架,并同时测量两种情况,以促进对 PPOU 和 CPSP 的科学认识。暂无数据。
{"title":"Risk factors for persistent postoperative opioid use: an entity distinct from chronic postsurgical pain","authors":"Sama Ramo, Stephan Frangakis, Jennifer F Waljee, Mark C Bicket","doi":"10.1136/rapm-2024-105599","DOIUrl":"https://doi.org/10.1136/rapm-2024-105599","url":null,"abstract":"Despite a decline in opioid prescriptions over the past decade, patients commonly receive opioid analgesics as a treatment for postoperative pain in the USA. One complication that patients may experience after surgery is persistent postoperative opioid use (PPOU), or opioid use beyond the typical recovery period. Often defined as beyond 3 months postsurgery, PPOU is frequently conflated with chronic postsurgical pain (CPSP), where pain persists well after the expected healing time following surgery. This narrative review explores the distinct risk factors for each condition, their interrelation, and potential future research directions. For PPOU, major risk factors include the risky use of substances including misuse and use disorders; depression and other mental health disorders; a history of chronic pain before surgery including back pain; and certain surgical types (ie, total knee arthropathy, open cholecystectomy, total hip arthropathy). Conversely, CPSP risk factors include the type of surgery (ie, thoracic and breast surgeries), mental health conditions (particularly catastrophizing), and pain in both the preoperative and postoperative phases. Despite the overlap of some factors, studies typically employ different frameworks when examining PPOU and CPSP, with a biopsychosocial model applied for CPSP and little emphasis on an individual’s social environment employed for PPOU. Additionally, existing studies predominantly rely on retrospective insurance claims data, which may not capture the full scope of risk factors. To fill gaps in understanding, investigations may prospectively assess and analyze patient-reported outcomes, implement similar frameworks, and concurrently measure both conditions to advance the scientific understanding of PPOU and CPSP. No data are available.","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative epidural analgesia and outcomes following pediatric bilateral lung and heart-lung transplantation: a retrospective observational study 小儿双肺和心肺移植术后硬膜外镇痛与疗效:一项回顾性观察研究
Pub Date : 2024-09-11 DOI: 10.1136/rapm-2024-105654
Kerry McLaughlin, Alex Konstantatos, Shravya Karna, Stuart Azzopardi, Mark Buckland, Harry Sivakumar, Ron Glick, Mycah Astrera-Srgo, Eldho Paul
Background The value of epidural analgesia in pediatric patients having heart and lung transplant surgery is unknown. We aimed to characterize various quality outcomes in patients who did and did not have epidural analgesia. Methods Data were collected retrospectively for 62 patients from 2006 to 2023 at a tertiary care transplant center. Patients were evaluated by epidural status. The primary outcome was a hospital stay in days. Other measures of morbidity and mortality were measured as secondary endpoints. Results The mean age was 12.7 (3) years; 54 (87%) received bilateral lung transplantation, and 8 (13%) received en bloc heart-lung transplantation. 41 (66%) were female. Epidural utilization rate was 74 %, n=45. On univariate analysis, epidural analgesia compared with no epidural was associated with a reduction in the median length of hospital stay from 26.5 to 20 days (p=0.02). After adjustment for age, sex and type of operation, there was no significant difference in LOS. Other findings following univariate analysis included reduced time of postoperative ventilation with a median reduction of 7–2 days (p=0.019), and a reduced 5-day postoperative opioid requirement; median of 2.94–1.21 mg/kg/24 hours (p=0.004) with epidural analgesia. Epidural analgesia was not associated with a change in overall survival (p=0.49). Conclusion Despite a likely improvement in analgesia, we could not demonstrate a definitive impact of epidural analgesia on outcomes in this small cohort of patients. Larger datasets through registries and institutional collaboration will be needed to increase sample size to identify effect sizes and adjust for confounders. Data may be obtained from a third party and are not publicly available. All data relevant to the study are included in the article or uploaded as online supplemental information. We are happy for all free text entered below to be published.
背景 硬膜外镇痛对接受心肺移植手术的儿科患者的价值尚不清楚。我们的目的是描述接受和未接受硬膜外镇痛的患者的各种质量结果。方法 回顾性收集了一家三级医疗移植中心 2006 年至 2023 年期间 62 名患者的数据。根据硬膜外状态对患者进行评估。主要结果是住院天数。其他发病率和死亡率指标作为次要终点进行测量。结果 平均年龄为12.7(3)岁;54人(87%)接受了双侧肺移植,8人(13%)接受了整体心肺移植。41例(66%)为女性。硬膜外使用率为 74%,n=45。经单变量分析,硬膜外镇痛与无硬膜外镇痛相比,中位住院时间从26.5天缩短至20天(P=0.02)。在对年龄、性别和手术类型进行调整后,住院时间没有显著差异。单变量分析的其他结果包括:术后通气时间缩短,中位数缩短了7-2天(P=0.019);术后5天阿片类药物需求量减少;硬膜外镇痛的中位数为2.94-1.21 mg/kg/24小时(P=0.004)。硬膜外镇痛与总生存率的变化无关(p=0.49)。结论 尽管镇痛效果可能有所改善,但我们无法证明硬膜外镇痛对这一小群患者的预后有明确影响。需要通过登记处和机构合作建立更大的数据集,以增加样本量,从而确定效应大小并调整混杂因素。数据可能从第三方获得,不对外公开。所有与研究相关的数据均包含在文章中或作为在线补充信息上传。我们乐于发表下面输入的所有自由文本。
{"title":"Postoperative epidural analgesia and outcomes following pediatric bilateral lung and heart-lung transplantation: a retrospective observational study","authors":"Kerry McLaughlin, Alex Konstantatos, Shravya Karna, Stuart Azzopardi, Mark Buckland, Harry Sivakumar, Ron Glick, Mycah Astrera-Srgo, Eldho Paul","doi":"10.1136/rapm-2024-105654","DOIUrl":"https://doi.org/10.1136/rapm-2024-105654","url":null,"abstract":"Background The value of epidural analgesia in pediatric patients having heart and lung transplant surgery is unknown. We aimed to characterize various quality outcomes in patients who did and did not have epidural analgesia. Methods Data were collected retrospectively for 62 patients from 2006 to 2023 at a tertiary care transplant center. Patients were evaluated by epidural status. The primary outcome was a hospital stay in days. Other measures of morbidity and mortality were measured as secondary endpoints. Results The mean age was 12.7 (3) years; 54 (87%) received bilateral lung transplantation, and 8 (13%) received en bloc heart-lung transplantation. 41 (66%) were female. Epidural utilization rate was 74 %, n=45. On univariate analysis, epidural analgesia compared with no epidural was associated with a reduction in the median length of hospital stay from 26.5 to 20 days (p=0.02). After adjustment for age, sex and type of operation, there was no significant difference in LOS. Other findings following univariate analysis included reduced time of postoperative ventilation with a median reduction of 7–2 days (p=0.019), and a reduced 5-day postoperative opioid requirement; median of 2.94–1.21 mg/kg/24 hours (p=0.004) with epidural analgesia. Epidural analgesia was not associated with a change in overall survival (p=0.49). Conclusion Despite a likely improvement in analgesia, we could not demonstrate a definitive impact of epidural analgesia on outcomes in this small cohort of patients. Larger datasets through registries and institutional collaboration will be needed to increase sample size to identify effect sizes and adjust for confounders. Data may be obtained from a third party and are not publicly available. All data relevant to the study are included in the article or uploaded as online supplemental information. We are happy for all free text entered below to be published.","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI-derived abdominal adipose tissue is associated with multisite and widespread chronic pain MRI 导出的腹部脂肪组织与多部位和广泛的慢性疼痛有关
Pub Date : 2024-09-10 DOI: 10.1136/rapm-2024-105535
Zemene Demelash Kifle, Jing Tian, Dawn Aitken, Phillip E Melton, Flavia Cicuttini, Graeme Jones, Feng Pan
Introduction Musculoskeletal pain typically occurs in multiple sites; however, no study has examined whether excessive visceral and subcutaneous adipose tissue are associated with musculoskeletal pain. This study therefore aimed to describe the associations between MRI-derived abdominal adipose tissue and multisite and widespread chronic musculoskeletal pain. Methods Data from the UK Biobank, a large prospective, population-based cohort study, were used. Abdominal MRI scans were performed at two imaging visits to quantify visceral adipose tissue and subcutaneous adipose tissue. Pain in the neck/shoulder, back, hip, knee or ‘all over the body’ was assessed at the corresponding visits. Mixed-effects ordinal/multinomial/logistic regression models were used for the analyses. Results A total of 32 409 participants were included (50.8% women, mean age 55.0±7.4 years). In multivariable analyses, there was a dose–response association of visceral adipose tissue, subcutaneous adipose tissue and their ratio with the number of chronic pain sites in both women (visceral adipose tissue: OR 2.04 per SD (95% CI 1.85 to 2.26); subcutaneous adipose tissue: OR 1.60 (95% CI 1.50 to 1.70); and their ratio: OR 1.60 (95% CI 1.37 to 1.87)) and men (visceral adipose tissue: OR 1.34 (95% CI 1.26 to 1.42); subcutaneous adipose tissue: OR 1.39 (95% CI 1.29 to 1.49); and their ratio: OR 1.13 (95% CI 1.07 to 1.20)). Higher levels of adipose tissue were also associated with greater odds of reporting chronic pain in both sexes. The effect estimates of these adipose measures were relatively larger in women than in men. Conclusion Abdominal adipose tissue was associated with chronic musculoskeletal pain, suggesting that excessive and ectopic fat depositions may be involved in the pathogenesis of multisite and widespread chronic musculoskeletal pain. The identified stronger effects in women than men may reflect sex differences in fat distribution and hormones. Data from the UK Biobank is available to researchers by application via the UK Biobank online Access Management System.
引言 肌肉骨骼疼痛通常发生在多个部位;然而,还没有研究探讨过多的内脏和皮下脂肪组织是否与肌肉骨骼疼痛有关。因此,本研究旨在描述 MRI 导出的腹部脂肪组织与多部位和广泛慢性肌肉骨骼疼痛之间的关联。方法 采用英国生物库的数据,这是一项大型前瞻性人群队列研究。在两次造影检查中进行了腹部核磁共振扫描,以量化内脏脂肪组织和皮下脂肪组织。颈部/肩部、背部、臀部、膝部或 "全身 "疼痛则在相应的检查中进行评估。分析采用混合效应序数/多项式/逻辑回归模型。结果 共纳入 32 409 名参与者(50.8% 为女性,平均年龄为 55.0±7.4 岁)。OR 2.04 per SD (95% CI 1.85 to 2.26);皮下脂肪组织:OR1.60(95% CI 1.50 至 1.70);及其比率:OR 1.60 (95% CI 1.37 to 1.87))和男性(内脏脂肪组织:内脏脂肪组织:OR 1.34(95% CI 1.26 至 1.42);皮下脂肪组织:内脏脂肪组织:OR 1.34(95% CI 1.26 至 1.42);皮下脂肪组织:OR 1.39(95% CI 1.29 至 1.49);两者的比率:OR 1.13(95% CI 1.29 至 1.49):OR 1.13 (95% CI 1.07 to 1.20))。脂肪组织水平越高,男女报告慢性疼痛的几率越大。这些脂肪测量指标对女性的影响估计值相对大于男性。结论 腹部脂肪组织与慢性肌肉骨骼疼痛有关,表明过量和异位脂肪沉积可能与多部位和广泛的慢性肌肉骨骼疼痛的发病机制有关。与男性相比,女性受到的影响更大,这可能反映了脂肪分布和荷尔蒙的性别差异。研究人员可通过英国生物库在线访问管理系统申请获取英国生物库的数据。
{"title":"MRI-derived abdominal adipose tissue is associated with multisite and widespread chronic pain","authors":"Zemene Demelash Kifle, Jing Tian, Dawn Aitken, Phillip E Melton, Flavia Cicuttini, Graeme Jones, Feng Pan","doi":"10.1136/rapm-2024-105535","DOIUrl":"https://doi.org/10.1136/rapm-2024-105535","url":null,"abstract":"Introduction Musculoskeletal pain typically occurs in multiple sites; however, no study has examined whether excessive visceral and subcutaneous adipose tissue are associated with musculoskeletal pain. This study therefore aimed to describe the associations between MRI-derived abdominal adipose tissue and multisite and widespread chronic musculoskeletal pain. Methods Data from the UK Biobank, a large prospective, population-based cohort study, were used. Abdominal MRI scans were performed at two imaging visits to quantify visceral adipose tissue and subcutaneous adipose tissue. Pain in the neck/shoulder, back, hip, knee or ‘all over the body’ was assessed at the corresponding visits. Mixed-effects ordinal/multinomial/logistic regression models were used for the analyses. Results A total of 32 409 participants were included (50.8% women, mean age 55.0±7.4 years). In multivariable analyses, there was a dose–response association of visceral adipose tissue, subcutaneous adipose tissue and their ratio with the number of chronic pain sites in both women (visceral adipose tissue: OR 2.04 per SD (95% CI 1.85 to 2.26); subcutaneous adipose tissue: OR 1.60 (95% CI 1.50 to 1.70); and their ratio: OR 1.60 (95% CI 1.37 to 1.87)) and men (visceral adipose tissue: OR 1.34 (95% CI 1.26 to 1.42); subcutaneous adipose tissue: OR 1.39 (95% CI 1.29 to 1.49); and their ratio: OR 1.13 (95% CI 1.07 to 1.20)). Higher levels of adipose tissue were also associated with greater odds of reporting chronic pain in both sexes. The effect estimates of these adipose measures were relatively larger in women than in men. Conclusion Abdominal adipose tissue was associated with chronic musculoskeletal pain, suggesting that excessive and ectopic fat depositions may be involved in the pathogenesis of multisite and widespread chronic musculoskeletal pain. The identified stronger effects in women than men may reflect sex differences in fat distribution and hormones. Data from the UK Biobank is available to researchers by application via the UK Biobank online Access Management System.","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conversion to general anesthesia and intravenous supplementation during intrapartum cesarean delivery with an indwelling epidural catheter: a retrospective study 使用留置硬膜外导管进行产前剖宫产时转为全身麻醉和静脉补充:一项回顾性研究
Pub Date : 2024-07-14 DOI: 10.1136/rapm-2024-105388
Michael Yohay Stav, Shai Fein, Yuri Matatov, Dana Hoffman, Philip Heesen, Yair Binyamin, Daniel Iluz-Freundlich, Leonid Eidelman, Sharon Orbach-Zinger
Background Intraoperative pain during cesarean delivery with or without conversion to general anesthesia has been shown to negatively impact maternal and perinatal morbidity. Efforts to reduce these adverse events are a recent focus of obstetric anesthesia care. We aimed to assess rates of and risk factors for conversion to general anesthesia and intraoperative pain during intrapartum cesarean delivery with an indwelling epidural catheter in our academic center. Methods In this retrospective cohort study, all women undergoing cesarean delivery with an indwelling epidural catheter between January 2017 and June 2022 were included. Labor epidural analgesia was provided according to a standardized protocol, and conversion to epidural anesthesia was achieved in the operating room before surgery. We determined the conversion rate to general anesthesia and associated risk factors. Second, we examined the rate of administration of analgesics/sedatives and related risk factors in cesarean cases that were not converted to general anesthesia. Results Among the 1192 women undergoing intrapartum cesarean delivery with epidural anesthesia, there were 97 cases with conversion to general anesthesia (8.1%), of which 87 (89.7%) were due to a failed epidural. Higher age, higher weight, and higher gestational age were associated with decreased odds of conversion to general anesthesia. Higher gravidity and longer surgical time were associated with increased odds. An emergent indication was not associated with conversion to general anesthesia. Intravenous analgesic/sedative supplementation occurred in 141 cases (12.9%). Higher age was associated with decreased odds of supplementation, and longer surgical time was associated with increased odds. Conclusion In our tertiary academic center, the rate of intraoperative conversion to general anesthesia and administration of analgesic/sedative medication among women undergoing intrapartum cesarean delivery with epidural anesthesia was relatively high. Emergency cesarean delivery was not associated with either of the above endpoints. Data are available upon reasonable request.
背景剖宫产术中疼痛无论是否转为全身麻醉,都会对产妇和围产期发病率产生负面影响。努力减少这些不良事件是近期产科麻醉护理的重点。我们的目的是评估在我们的学术中心,使用留置硬膜外导管进行产中剖宫产时转为全身麻醉和术中疼痛的发生率和风险因素。方法 在这项回顾性队列研究中,纳入了 2017 年 1 月至 2022 年 6 月期间所有使用留置硬膜外导管进行剖宫产的产妇。根据标准化方案提供分娩硬膜外镇痛,手术前在手术室实现硬膜外麻醉转换。我们确定了全身麻醉的转换率和相关风险因素。其次,我们研究了未转为全身麻醉的剖宫产病例的镇痛剂/镇静剂使用率及相关风险因素。结果 在接受硬膜外麻醉的 1192 名产后剖宫产产妇中,有 97 例(8.1%)转为全身麻醉,其中 87 例(89.7%)是因为硬膜外麻醉失败。年龄越大、体重越重、胎龄越大,转为全身麻醉的几率越小。孕周越大、手术时间越长,转为全身麻醉的几率越高。紧急指征与转为全身麻醉无关。141例(12.9%)患者使用了静脉镇痛剂/镇静剂。年龄越大,补充的几率越低,手术时间越长,几率越高。结论 在我们的三级学术中心,接受硬膜外麻醉的产内剖宫产妇女术中转为全身麻醉和使用镇痛/镇静药物的比例相对较高。紧急剖宫产与上述终点均无关联。如有合理要求,可提供相关数据。
{"title":"Conversion to general anesthesia and intravenous supplementation during intrapartum cesarean delivery with an indwelling epidural catheter: a retrospective study","authors":"Michael Yohay Stav, Shai Fein, Yuri Matatov, Dana Hoffman, Philip Heesen, Yair Binyamin, Daniel Iluz-Freundlich, Leonid Eidelman, Sharon Orbach-Zinger","doi":"10.1136/rapm-2024-105388","DOIUrl":"https://doi.org/10.1136/rapm-2024-105388","url":null,"abstract":"Background Intraoperative pain during cesarean delivery with or without conversion to general anesthesia has been shown to negatively impact maternal and perinatal morbidity. Efforts to reduce these adverse events are a recent focus of obstetric anesthesia care. We aimed to assess rates of and risk factors for conversion to general anesthesia and intraoperative pain during intrapartum cesarean delivery with an indwelling epidural catheter in our academic center. Methods In this retrospective cohort study, all women undergoing cesarean delivery with an indwelling epidural catheter between January 2017 and June 2022 were included. Labor epidural analgesia was provided according to a standardized protocol, and conversion to epidural anesthesia was achieved in the operating room before surgery. We determined the conversion rate to general anesthesia and associated risk factors. Second, we examined the rate of administration of analgesics/sedatives and related risk factors in cesarean cases that were not converted to general anesthesia. Results Among the 1192 women undergoing intrapartum cesarean delivery with epidural anesthesia, there were 97 cases with conversion to general anesthesia (8.1%), of which 87 (89.7%) were due to a failed epidural. Higher age, higher weight, and higher gestational age were associated with decreased odds of conversion to general anesthesia. Higher gravidity and longer surgical time were associated with increased odds. An emergent indication was not associated with conversion to general anesthesia. Intravenous analgesic/sedative supplementation occurred in 141 cases (12.9%). Higher age was associated with decreased odds of supplementation, and longer surgical time was associated with increased odds. Conclusion In our tertiary academic center, the rate of intraoperative conversion to general anesthesia and administration of analgesic/sedative medication among women undergoing intrapartum cesarean delivery with epidural anesthesia was relatively high. Emergency cesarean delivery was not associated with either of the above endpoints. Data are available upon reasonable request.","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141612057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing effects of adding regional blocks to multimodal analgesia regimen on quality of postoperative recovery 比较在多模式镇痛方案中增加区域阻滞对术后恢复质量的影响
Pub Date : 2024-07-14 DOI: 10.1136/rapm-2024-105717
Fu-Shan Xue, Daoyi Lin, Xiao-Chun Zheng
By conducting a prospective randomised open-label non-inferiority trial in 90 patients who underwent elective unilateral video-assisted lobectomy or wedge resection, van den Broek et al [1][1] compared the effects of adding continuous erector spinae plane block and thoracic epidural analgesia into a
van den Broek 等人[1][1] 在 90 名接受选择性单侧视频辅助肺叶切除术或楔形切除术的患者中进行了一项前瞻性随机开放标签非劣效性试验,比较了将持续竖脊肌平面阻滞和胸硬膜外镇痛添加到楔形切除术中的效果。
{"title":"Comparing effects of adding regional blocks to multimodal analgesia regimen on quality of postoperative recovery","authors":"Fu-Shan Xue, Daoyi Lin, Xiao-Chun Zheng","doi":"10.1136/rapm-2024-105717","DOIUrl":"https://doi.org/10.1136/rapm-2024-105717","url":null,"abstract":"By conducting a prospective randomised open-label non-inferiority trial in 90 patients who underwent elective unilateral video-assisted lobectomy or wedge resection, van den Broek et al [1][1] compared the effects of adding continuous erector spinae plane block and thoracic epidural analgesia into a","PeriodicalId":21046,"journal":{"name":"Regional Anesthesia & Pain Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141612058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Regional Anesthesia & Pain Medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1