Treating moderate-to-severe menopausal vasomotor symptoms with fezolinetant: analysis of responders using pooled data from two phase 3 studies (SKYLIGHT 1 and 2).

Rossella E Nappi, Kimball A Johnson, Petra Stute, Martin Blogg, Marci English, Antonia Morga, Ludmila Scrine, Emad Siddiqui, Faith D Ottery
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Abstract

The aims of the study were to further characterize the efficacy of fezolinetant for the treatment of moderate-to-severe vasomotor symptoms (VMS) due to menopause using responder analysis and to investigate whether efficacy, not adjusted for placebo, resulted in clinically meaningful within-patient change.
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使用非索内酯治疗中重度更年期血管运动症状:利用两项三期研究(SKYLIGHT 1 和 2)的汇总数据分析应答者。
该研究的目的是利用应答者分析法进一步确定非佐利奈坦治疗更年期引起的中度至重度血管运动症状(VMS)的疗效,并研究在未对安慰剂进行调整的情况下,疗效是否会导致患者内部发生有临床意义的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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