Mistranslating the genetic code with leucine in yeast and mammalian cells

IF 3.6 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY RNA Biology Pub Date : 2024-04-17 DOI:10.1080/15476286.2024.2340297
Josephine Davey-Young, Farah Hasan, Rasangi Tennakoon, Peter Rozik, Henry Moore, Peter Hall, Ecaterina Cozma, Julie Genereaux, Kyle S. Hoffman, Patricia P. Chan, Todd M. Lowe, Christopher J. Brandl, Patrick O’Donoghue
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引用次数: 0

Abstract

Translation fidelity relies on accurate aminoacylation of transfer RNAs (tRNAs) by aminoacyl-tRNA synthetases (AARSs). AARSs specific for alanine (Ala), leucine (Leu), serine, and pyrrolysine do no...
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在酵母和哺乳动物细胞中用亮氨酸错译遗传密码
翻译的保真度有赖于氨基酰-tRNA 合成酶(AARS)对转移 RNA(tRNA)进行准确的氨基酰化。对丙氨酸 (Ala)、亮氨酸 (Leu)、丝氨酸和吡咯赖氨酸具有特异性的 AARSs 不...
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来源期刊
RNA Biology
RNA Biology 生物-生化与分子生物学
CiteScore
8.60
自引率
0.00%
发文量
82
审稿时长
1 months
期刊介绍: RNA has played a central role in all cellular processes since the beginning of life: decoding the genome, regulating gene expression, mediating molecular interactions, catalyzing chemical reactions. RNA Biology, as a leading journal in the field, provides a platform for presenting and discussing cutting-edge RNA research. RNA Biology brings together a multidisciplinary community of scientists working in the areas of: Transcription and splicing Post-transcriptional regulation of gene expression Non-coding RNAs RNA localization Translation and catalysis by RNA Structural biology Bioinformatics RNA in disease and therapy
期刊最新文献
An orthology-based methodology as a complementary approach to retrieve evolutionarily conserved A-to-I RNA editing sites. A systematic analysis of circRNAs in subnuclear compartments. Silencing LINC00663 inhibits inflammation and angiogenesis through downregulation of NR2F1 via EBF1 in bladder cancer Mistranslating the genetic code with leucine in yeast and mammalian cells The regulatory roles of small nucleolar RNAs within their host locus
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