Prevalence of crimean Congo hemorrhagic fever in Khyber Pakhtunkhwa, Pakistan

IF 6.3 3区医学 Q1 INFECTIOUS DISEASES Travel Medicine and Infectious Disease Pub Date : 2024-04-18 DOI:10.1016/j.tmaid.2024.102722

Asad Zia , Ali Talha Khalil , Naz Alam , Abdul Qadoos Khan , Mubarak Ali Khan , Yasar Yosafzai , Asif Ali , Ihsan Ullah , Ali Rehman Wazir

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Abstract

Background

CCHFV is well recognized as a major public health threat and its prevalence and epidemiological distribution in Pakistan and specifically in KP province is not well documented.

Methods

We used a gold-standard PCR-based diagnostic assay for confirmation of CCHFV among suspected patients. A total of 150 patients were enrolled from June 2022 to September 2022 and their blood samples were collected for PCR confirmation.

Results

The overall positivity rate for CCHFV was 26.67 %, with the virus mostly prevalent in the middle-aged group (21–40 years). In the July of 2022, a significant spike in the prevalence of CCHFV was observed in provincial capital Peshawar with the highest burden (31.57 %).

Conclusion

Our findings indicate the necessity of strengthening CCHFV monitoring programs and intensifying efforts to identify hotspot regions for effective surveillance and control of CCHFV. The months before the Eid-ul-Adha are crucial in the context of CCHFV control.

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巴基斯坦开伯尔巴图克瓦省的刚果出血热流行情况

背景CCHFV被公认为是一种重大的公共卫生威胁，但其在巴基斯坦，特别是在KP省的流行率和流行病学分布却没有得到很好的记录。结果CCHFV的总体阳性率为26.67%，病毒主要流行于中年群体（21-40岁）。结论我们的研究结果表明，有必要加强 CCHFV 监测项目，并加大力度确定热点地区，以有效监测和控制 CCHFV。宰牲节前的几个月是控制 CCHFV 的关键时期。

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来源期刊

Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

19.40

自引率

1.70%

发文量

211

审稿时长

49 days

期刊介绍： Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers