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A case report on symptomatic disease caused by serotype 4 vaccine virus following tetravalent anti-dengue vaccination 接种四价抗登革热疫苗后血清 4 型疫苗病毒引发症状性疾病的病例报告。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-24 DOI: 10.1016/j.tmaid.2024.102782
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引用次数: 0
Global spread of mpox Clade I: Implications for travel and public health mpox Clade I 的全球传播:对旅行和公共卫生的影响。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-24 DOI: 10.1016/j.tmaid.2024.102781
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引用次数: 0
Characteristics and morbidity patterns of last-minute travelers in Thailand 泰国最后一分钟旅行者的特征和发病模式。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-22 DOI: 10.1016/j.tmaid.2024.102780

Background

Last-minute travelers (LMTs) present significant challenges for travel health services and are considered vulnerable due to their lack of health preparation. However, there is a lack of data to support this assumption.

Methods

The proportion of LMTs was investigated through a cross-sectional study involving all Thai travelers who visited the Thai Travel Clinic before their departure abroad. A prospective study was conducted by enrolling the travelers after the consultation, utilizing two online questionnaires. The first aimed to gather demographic data and categorize participants as either LMTs (if their departure date was ≤14 days) or non-LMTs, while the second assessed travel-related illnesses either upon their return or at the one-month point if their trip exceeded a month.

Results

A quarter (25.5 %) of 310 Thai travelers abroad were classified as LMTs. Both LMTs and non-LMTs showed similar gender distributions with mean ages of 35.8 and 35.7 years old, respectively, but LMTs were more likely to travel for tourism, travel in groups, visit countries within Asia and plan shorter stays abroad. Follow-up studies were conducted from July 2023 to February 2024. 452 departed respondents consisted of 150 LMTs and 302 non-LMTs. Although overall health problems were insignificantly higher in LMTs (32.0 % vs 22.0 %, AOR = 1.469, p = 0.107), gastrointestinal and neurological symptoms (primarily headache and dizziness) were significantly more common among LMTs.

Conclusions

LMTs represent a significant portion of Thai travelers, posing challenges for travel health specialists in Thailand. Intervention and education efforts may be necessary to address this issue.
背景:临时旅客(LMTs)给旅行健康服务带来了巨大挑战,由于他们缺乏健康准备,因此被认为是弱势群体。然而,目前还缺乏支持这一假设的数据:方法:通过一项横断面研究,调查了所有在出国前前往泰国旅行诊所就诊的泰国旅行者中 LMT 的比例。前瞻性研究是在咨询结束后,利用两份在线问卷对旅行者进行登记。第一份问卷旨在收集人口统计学数据,并将参与者分为LMT(如果出发日期不超过14天)和非LMT,第二份问卷则评估旅行相关疾病,如果旅行超过一个月,则在回国后或一个月后进行:在 310 名出国旅行的泰国人中,四分之一(25.5%)被归类为 LMT。LMT 和非 LMT 的性别分布相似,平均年龄分别为 35.8 岁和 35.7 岁,但 LMT 更倾向于旅游观光、组团旅行、访问亚洲国家和计划较短的海外停留时间。跟踪研究于 2023 年 7 月至 2024 年 2 月进行。452 名离境受访者包括 150 名 LMT 和 302 名非 LMT。虽然 LMT 的总体健康问题显著高于非 LMT(32.0% vs 22.0%,AOR = 1.469,p = 0.107),但胃肠道和神经系统症状(主要是头痛和头晕)在 LMT 中更为常见:结论:LMT 占泰国旅行者的很大一部分,给泰国的旅行健康专家带来了挑战。为解决这一问题,可能有必要开展干预和教育工作。
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引用次数: 0
Unmasking hidden risks: A case of primaquine-induced intravascular hemolysis in G-6-PD deficient malaria patient 揭开隐藏的风险:一例 G-6-PD 缺乏的疟疾患者因普利马喹引起的血管内溶血。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-18 DOI: 10.1016/j.tmaid.2024.102777
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引用次数: 0
Concurrent strongyloidiasis and necatoriasis in a Cambodian technical intern trainee in Japan that committed suicide: Diagnosis prompted by Taenia saginata proglottids in watery diarrhea 一名在日本自杀的柬埔寨技术实习生同时患有强直性脊柱炎和坏死性脊柱炎:由水样腹泻中的矢车菊原虫引起的诊断。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-18 DOI: 10.1016/j.tmaid.2024.102778
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引用次数: 0
Epidemiologic trends and clinical outcomes of imported malaria in a tertiary care hospital, Bangkok, Thailand: A retrospective analysis (2013–2022) 泰国曼谷一家三甲医院输入性疟疾的流行趋势和临床结果:回顾性分析(2013-2022 年)。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-18 DOI: 10.1016/j.tmaid.2024.102775

Background

Despite a significant declined in malaria incidence in Thailand, the rising global travel has resulted in an increase of imported malaria cases, posing a threat to the goal of malaria elimination. This study aims to understand the epidemiological trends and clinical outcomes of imported malaria cases in Thailand.

Methods

Medical records of all imported malaria cases admitted from 1st January 2013 to 31st December 2022 at the Hospital for Tropical Diseases, Thailand, were retrospectively examined. Demographic data, travel details, severity of illness, and clinical outcomes were described. Logistic regression was performed to identify factors associated with severe disease outcomes.

Results

In total, 335 cases of imported malaria were identified, with 33 % classified as transnational malaria and 67 % as border malaria. Transnational malaria cases (79 % P. falciparum) were mostly acquired from Sub-Saharan Africa for business or visiting friends and relatives (VFRs). Border malaria cases (81 % P. vivax) involved unskilled labourers and were acquired from land-border countries. The proportion of imported malaria in business travelers increased from 13 % to 50 % over the ten years. Risk factors for severe imported malaria included male gender, age 40 and older, infection with P. falciparum, and acquired malaria from Africa.

Conclusions

Understanding unique demographic and socioeconomic characteristics in both border and transnational cases is crucial for effective malaria prevention. The increasing imported malaria among business travelers highlight the need for targeted prevention in this high-risk group.
背景:尽管泰国的疟疾发病率大幅下降,但全球旅行的增加导致输入性疟疾病例的增加,对实现消灭疟疾的目标构成威胁。本研究旨在了解泰国输入性疟疾病例的流行趋势和临床结果:回顾性研究了泰国热带病医院从 2013 年 1 月 1 日至 2022 年 12 月 31 日收治的所有输入性疟疾病例的医疗记录。对人口统计学数据、旅行细节、病情严重程度和临床结果进行了描述。采用逻辑回归法确定与严重疾病结果相关的因素:共发现 335 例输入性疟疾病例,其中 33% 为跨国疟疾,67% 为边境疟疾。跨国疟疾病例(79%为恶性疟原虫)大多来自撒哈拉以南非洲,目的是出差或探亲访友(VFRs)。边境疟疾病例(81% 为间日疟原虫)涉及非熟练工人,来自陆地边境国家。十年间,商务旅客中的输入性疟疾病例比例从 13% 上升到 50%。严重输入性疟疾的风险因素包括男性、40 岁及以上、感染恶性疟原虫以及从非洲获得疟疾:了解边境和跨国病例中独特的人口和社会经济特征对于有效预防疟疾至关重要。商务旅行者中输入性疟疾日益增多,这突出表明需要对这一高风险群体进行有针对性的预防。
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引用次数: 0
Emergence of cutaneous anthrax in a case with non-stock farming professional woman: The need for heightened surveillance and public health readiness 非畜牧业职业女性皮肤炭疽病例:加强监测和公共卫生准备的必要性。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-18 DOI: 10.1016/j.tmaid.2024.102779
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引用次数: 0
Post-migration infection with SARS-CoV-2 in Venezuelan migrants: A laboratory-based epidemiological observational study 委内瑞拉移民移居国外后感染 SARS-CoV-2 的情况:一项基于实验室的流行病学观察研究。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-17 DOI: 10.1016/j.tmaid.2024.102772

Background

Since 2015, over 6 million Venezuelans migrated to Colombia and neighboring countries. While most people adhered to lockdown measures, migrants kept moving during the COVID-19 pandemic.

Method

To investigate the extent of migration-associated SARS-CoV-2 infections, we interviewed 1209 adult Venezuelan migrants upon arrival to Bucaramanga, Colombia, 200 km from the Colombian-Venezuelan border along the main migration route during April–September 2021, collected individual-level socio-economic and clinical data, sampled blood and saliva, and assessed SARS-CoV-2 infection by serological, molecular and phylogenetic tools.

Results

SARS-CoV-2 RT-PCR positivity was 1.9 % (95 % Confidence Interval (CI), 1.2–2.9) without varying significantly over the study period (chi-square, p = 0.922) and significantly associated with stay in Colombia >14 days (p = 0.018; prevalence ratio 3.3, 95 % CI, 1.2–8.7). Pre-existing SARS-CoV-2-specific antibodies were neither significantly associated with preventing infection (Chi-square, p = 0.188), nor symptom development (Fisher, p = 0.246). Predominance and time of detection of SARS-CoV-2 Mu and Gamma variants in migrants in comparison to available genomic data suggested infection predominantly in Colombia. SARS-CoV-2 IgG-based seroprevalence was 34.2 % (95 % CI, 31.5–36.9). Detection of SARS-CoV-2-specific antibodies was significantly associated with previous contact with infected individuals (p = 0.002).

Conclusions

SARS-CoV-2 infection occurred predominantly after immigration, potentially facilitated by densely populated border camps. Improved infrastructure and health care will prevent migration-associated spread of COVID-19 and other infectious diseases.
背景:自 2015 年以来,超过 600 万委内瑞拉人移居到哥伦比亚及其邻国。虽然大多数人都遵守了封锁措施,但在 COVID-19 大流行期间,移民仍在不断迁移:为了调查与移民相关的 SARS-CoV-2 感染情况,我们在 2021 年 4 月至 9 月期间采访了抵达布卡拉曼加(Bucaramanga)的 1209 名委内瑞拉成年移民,该地距离哥伦比亚-委内瑞拉边境 200 公里,是主要的移民路线,我们收集了个人层面的社会经济和临床数据,采集了血液和唾液样本,并通过血清学、分子学和系统发生学工具评估了 SARS-CoV-2 感染情况:SARS-CoV-2 RT-PCR 阳性率为 1.9%(95% 置信区间 (CI),1.2-2.9),在研究期间无显著变化(卡方检验,p=0.922),与在哥伦比亚停留时间超过 14 天有显著关系(p=0.018;患病率比为 3.3,95% CI,1.2-8.7)。预先存在的 SARS-CoV-2 特异性抗体与预防感染(Chi-square,p=0.188)和症状发展(Fisher,p=0.246)均无明显关联。与现有基因组数据相比,移民中 SARS-CoV-2 Mu 和 Gamma 变体的主要特征和检测时间表明,感染主要发生在哥伦比亚。基于 SARS-CoV-2 IgG 的血清流行率为 34.2%(95% CI,31.5-36.9)。SARS-CoV-2特异性抗体的检测与之前与感染者的接触密切相关(P=0.002):结论:SARS-CoV-2 感染主要发生在移民之后,人口稠密的边境营地可能是促成感染的原因。改善基础设施和医疗保健将防止 COVID-19 和其他传染病在移民中传播。
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引用次数: 0
Hemorrhagic erucism due to Lonomia spp. in Peru – A call for action 秘鲁 Lonomia spp.引起的出血性糜烂 - 行动呼吁。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-16 DOI: 10.1016/j.tmaid.2024.102774
Envenomation due to exposure to caterpillars is an emerging public health problem. A life-threatening bleeding diathesis has been described in South America after exposure to Lonomia obliqua or L. acheolus. Deforestation, forest degradation, and global warming might increase the frequency of human exposure to these insects. Prompt recognition and administration of antivenom are crucial to ensure a favorable outcome.
因接触毛虫而引起的传染病是一个新出现的公共卫生问题。据描述,在南美洲,接触到 Lonomia obliqua 或 L. acheolus 后会出现危及生命的出血综合症。森林砍伐、森林退化和全球变暖可能会增加人类接触这些昆虫的频率。及时发现并注射抗蛇毒血清对确保治疗效果至关重要。
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引用次数: 0
Rising threat of Oropouche virus transmission from mother to child: An urgent call for action 奥罗普切病毒母婴传播的威胁日益严重:紧急行动呼吁》。
IF 6.3 3区 医学 Q1 INFECTIOUS DISEASES Pub Date : 2024-10-16 DOI: 10.1016/j.tmaid.2024.102776
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引用次数: 0
期刊
Travel Medicine and Infectious Disease
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