Metacognitive profiles in children and adolescents with obsessive-compulsive disorder

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1016/j.jocrd.2024.100874
Cecilie Schultz Isaksen , Per Hove Thomsen , Lara J. Farrell , Davíð R.M.A. Højgaard , Lidewij Wolters , Judith Nissen , Allison M. Waters , Katja A. Hybel
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Abstract

It has been suggested that maladaptive metacognition (beliefs and strategies) is related to the development and maintenance of obsessive-compulsive disorder (OCD). The aims of the study were to explore whether subgroups of pediatric OCD patients could be identified based on self-reported generic metacognition, and to compare these potential subgroups with a non-clinical control group. Additionally, differences between subgroups were examined across demographic (age and sex) and clinical characteristics (OCD severity and insight, types of OCD symptoms, and co-occurring symptoms). The study included a pooled sample of 157 pediatric OCD patients (age 7–18 years) and 58 non-clinical controls. Latent profile analyses supported a model with three profiles characterized by low, moderate, and high levels of maladaptive metacognition relative to the control group. Children and adolescents with higher age, greater OCD severity, specific OCD symptoms (e.g., aggressive, sexual, somatic, religious, and self-rated obsessing symptoms), and/or co-occurring internalizing symptoms (including anxiety and depressive symptoms) had a higher probability of belonging to a group with higher levels of maladaptive metacognition. The emergent profiles indicate heterogeneity in metacognition and clinical expression among children and adolescents with OCD, suggesting that generic metacognition could be a possible treatment target for some of these patients.

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患有强迫症的儿童和青少年的元认知特征
有人认为,适应不良的元认知(信念和策略)与强迫症(OCD)的发展和维持有关。本研究的目的是探讨能否根据自我报告的一般元认知识别出儿科强迫症患者的亚组,并将这些潜在亚组与非临床对照组进行比较。此外,研究还考察了不同人口统计学特征(年龄和性别)和临床特征(强迫症严重程度和洞察力、强迫症症状类型以及共存症状)的亚群之间的差异。该研究包括 157 名儿科强迫症患者(7-18 岁)和 58 名非临床对照者的集合样本。潜特征分析表明,相对于对照组,该模型具有低、中、高三种适应不良元认知特征。年龄越大、强迫症严重程度越高、有特定强迫症症状(如攻击性症状、性症状、躯体症状、宗教症状和自评强迫症状)和/或同时出现内化症状(包括焦虑和抑郁症状)的儿童和青少年,属于适应不良元认知水平较高组别的可能性越大。新出现的特征表明,患有强迫症的儿童和青少年在元认知和临床表现方面存在异质性,这表明通用元认知可能是其中一些患者的治疗目标。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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