Unsolved morphogenesis problems and the hidden order

IF 1.9 4区 生物学 Q2 BIOLOGY Biosystems Pub Date : 2024-05-01 Epub Date: 2024-04-21 DOI:10.1016/j.biosystems.2024.105218
A.V. Melkikh
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Abstract

In this work, the morphogenesis mechanisms are considered from the complexity perspective. It is shown that both morphogenesis and the functioning of organs should be unstable in the case of short-range interaction potentials. The repeatability of forms during evolution is a strong argument for its directionality. The formation of organs during evolution can occur only in the presence of a priori information about the structure of such an organ. The focus of the discussion is not merely on constraining potential possibilities but on the concept of directed evolution itself. A morphogenesis model was constructed based on nontrivial quantum effects. These interaction effects between biologically important molecules ensure the accurate synthesis of cells, tissues, and organs.

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悬而未决的形态发生问题和隐性秩序
这项工作从复杂性的角度考虑了形态发生机制。研究表明,在短程相互作用势的情况下,形态发生和器官的功能都应该是不稳定的。进化过程中形态的可重复性是其方向性的有力论据。进化过程中器官的形成只有在存在关于这种器官结构的先验信息的情况下才会发生。讨论的重点不仅仅是限制潜在的可能性,而是定向进化的概念本身。我们根据非微观量子效应构建了一个形态发生模型。这些生物重要分子之间的相互作用效应确保了细胞、组织和器官的精确合成。
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来源期刊
Biosystems
Biosystems 生物-生物学
CiteScore
3.70
自引率
18.80%
发文量
129
审稿时长
34 days
期刊介绍: BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.
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