Pharmacological treatments for psychotic depression

Y. W. Francis Lam Pharm.D., FCCP
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Abstract

Despite the overall efficacy of antidepressant and antipsychotic combination therapy for the treatment of psychotic depression, data on the most appropriate choice of individual drugs for the combination treatment are limited. Researchers recently conducted a network meta-analysis to compare the efficacy and safety of various pharmacological treatment options for patients who had major depressive episodes with psychotic features (Oliva et al., 2024).

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精神抑郁症的药物治疗
尽管抗抑郁剂和抗精神病药物联合疗法在治疗精神病性抑郁症方面总体疗效显著,但有关联合疗法中最合适的单药选择的数据却十分有限。研究人员最近进行了一项网络荟萃分析,比较了各种药物治疗方案对伴有精神病特征的重度抑郁发作患者的疗效和安全性(Oliva 等人,2024 年)。
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