Artificial intelligence model utilizing endometrial analysis to contribute as a predictor of assisted reproductive technology success

Abstract

This study addresses the development of EndoClassify, an artificial intelligence (AI) model designed to assess endometrial characteristics and enhance embryo receptivity. Utilizing a dataset of 402 endometrial ultrasound images augmented to 14.989, EndoClassify, incorporating Attention U-Net for image segmentation and GoogLeNet Inception for image classification, demonstrated exceptional performance with an accuracy of 95%, loss of 10%, a sensitivity of 93%, and specificity of 93%. The significance of EndoClassify extends beyond its robust metrics. This AI model has transformative potential in clinical settings, offering specialists a reliable, rapid, and accurate tool for endometrial assessment in assisted reproduction technology (ART) cycles. Identifying ‘good endometrium’ with 71% accuracy, corresponding to a 74% pregnancy rate, underscores EndoClassify’s role in significantly improving patient outcomes. In conclusion, the seamless integration of ultrasonographic parameters and AI techniques enhances efficiency in clinical decision-making and signifies a crucial collaboration between advanced technology and clinical expertise. While acknowledging the retrospective design as a limitation, it is imperative to highlight potential biases introduced by this design. Additionally, including fresh and frozen embryo transfers without known ploidy status adds transparency to the study’s limitations. EndoClassify stands as a beacon of progress, poised to revolutionize personalized treatment strategies and bring tangible benefits to specialists and patients in the dynamic landscape of assisted reproductive technology.