Exploring the Potential of Treating Sarcopenia through Dietary Interventions

IF 3.5 2区 农林科学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Food Biochemistry Pub Date : 2024-04-20 DOI:10.1155/2024/3018760
Shivangi Srivastava, Vinay Kumar Pandey, Anurag Singh, Aamir Hussain Dar
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Abstract

Sarcopenia, the age-related loss of muscle mass and function, is a growing concern as the global population continues to age. It is associated with physical disability, decreased quality of life, and increased risk of falls and fractures. Nutritional interventions have been suggested to be effective in the prevention and treatment of sarcopenia. According to cross-sectional studies, the prevalence of sarcopenia in people with heart failure (HF) is 38% for men and 32% for women, contributing to cardiac fragility, a lower quality of life, and an increased risk of death. A rising number of research studies have been performed to investigate the role of certain nutrients on muscle mass or function, as appropriate nutrition is crucial for muscle maintenance. The goal of this systematic review is to outline the present evidence for exercise and nutritional interventions as potential contributors to the treatment of sarcopenia and frailty (decreased muscle mass and physical function), as well as the threat of underlying cardiac metabolic comorbidity in individuals who have heart failure (HF), cancer, CVDs, and other health problems. The biochemical properties of natural foods play a crucial role in the prevention and treatment of sarcopenia. This review explores the effectiveness of nutritional interventions for the prevention and treatment of sarcopenia.

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探索通过饮食干预治疗 "肌肉疏松症 "的潜力
随着全球人口的不断老龄化,肌肉疏松症(与年龄有关的肌肉质量和功能丧失)日益引起人们的关注。它与身体残疾、生活质量下降以及跌倒和骨折风险增加有关。营养干预被认为对预防和治疗肌肉疏松症有效。根据横断面研究,在心力衰竭(HF)患者中,肌肉疏松症的发病率男性为 38%,女性为 32%,它会导致心脏脆弱、生活质量下降和死亡风险增加。由于适当的营养对肌肉的维持至关重要,因此越来越多的研究都在探讨某些营养素对肌肉质量或功能的作用。本系统综述的目的是概述运动和营养干预作为治疗肌肉疏松症和虚弱症(肌肉质量和身体功能下降)的潜在促进因素的现有证据,以及心力衰竭(HF)、癌症、心血管疾病和其他健康问题患者潜在的心脏代谢合并症的威胁。天然食物的生化特性在预防和治疗肌肉疏松症方面起着至关重要的作用。本综述探讨了预防和治疗肌肉疏松症的营养干预措施的有效性。
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来源期刊
Journal of Food Biochemistry
Journal of Food Biochemistry 生物-生化与分子生物学
CiteScore
7.80
自引率
5.00%
发文量
488
审稿时长
3.6 months
期刊介绍: The Journal of Food Biochemistry publishes fully peer-reviewed original research and review papers on the effects of handling, storage, and processing on the biochemical aspects of food tissues, systems, and bioactive compounds in the diet. Researchers in food science, food technology, biochemistry, and nutrition, particularly based in academia and industry, will find much of great use and interest in the journal. Coverage includes: -Biochemistry of postharvest/postmortem and processing problems -Enzyme chemistry and technology -Membrane biology and chemistry -Cell biology -Biophysics -Genetic expression -Pharmacological properties of food ingredients with an emphasis on the content of bioactive ingredients in foods Examples of topics covered in recently-published papers on two topics of current wide interest, nutraceuticals/functional foods and postharvest/postmortem, include the following: -Bioactive compounds found in foods, such as chocolate and herbs, as they affect serum cholesterol, diabetes, hypertension, and heart disease -The mechanism of the ripening process in fruit -The biogenesis of flavor precursors in meat -How biochemical changes in farm-raised fish are affecting processing and edible quality
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