The importance of ketamine for cerebral protection in pediatric cardiac surgery

A. Ivkin, E. V. Grigoriev
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Abstract

The problem of cerebral protection in cardiac surgery is relevant, despite all the techniques used. Due to its properties, ketamine can occupy its niche in solving this problem. The article analyzes current literature sources and describes the use of ketamine for analgesia, sedation and cerebral protection, and analyzes its properties for reducing the systemic inflammatory response. The mechanisms of its action and recommended doses are given, and schemes for its use both during anesthesia and the postoperative period are presented.
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氯胺酮在小儿心脏手术中保护大脑的重要性
尽管使用了各种技术,但心脏手术中的脑保护问题依然存在。氯胺酮因其特性可在解决这一问题方面占据一席之地。文章分析了目前的文献资料,介绍了氯胺酮在镇痛、镇静和脑保护方面的应用,并分析了其减轻全身炎症反应的特性。文章给出了氯胺酮的作用机制和推荐剂量,并介绍了在麻醉期间和术后使用氯胺酮的方案。
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