Analysis of essential hematological parameters and nutrient levels of dengue patients aiming for quick recovery and sustainable immunity

Abstract

Purpose: Dengue is one of the common public health issues globally where laboratory diagnostic test values of patients are primarily focused on hematological parameters. Micronutrients equally take a role in quick recovery, and active cum passive immunity is not mainly considered during and post-recovery of patients. Materials and Methods: A cross-sectional study with a purposive sampling method was applied using pre-tested close-ended questionnaires and laboratory data (soft copies/hard copies) of participants admitted to hospitals or nursing homes within the North -24 Paraganas district from November 2021 to October 2022. 110 male and female patients of 40-60 years reported dengue fever (non-hospitalized cases), and dengue hemorrhagic fever (hospitalized cases) was considered based on 15 variables. STATA version 18.0 software analyzed data using multivariate regression and range plots. The Cronbach’s alpha value was 0.72, and the consolidated probability value shows 0.01 (p<0.05), which denotes that the multivariate model was statistically significant and was rightly decided to include the relevant independent variables. Calcium, vitamin D, and total protein were statistically significant as P values were 0.01, the same for each. Similarly, p=0.05 was the same for Total Leukocyte count (TLC) and Alkaline phosphatase (ALP).The study concludes that micronutrients like calcium, protein, vitamin D, etc., are often considered secondary recommendations in dengue treatment. A balanced, nutrient-rich diet for dengue patients is needed to maintain sustained immunity by extensively monitoring calcium, vitamin D, and total protein intake during and after recovery.