Hemoglobin A1c levels and 1-year mortality in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention.

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-11 DOI:10.2217/fca-2023-0121
P. Izadpanah, Tara Dehghanzadeh, A. Attar, Alireza Hosseinpour, Nima Rahimikashkooli
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Abstract

Background: In this study, we investigated whether different levels of hemoglobin A1c (HbA1c) are associated with different short-term and 1-year mortality rates among diabetic patients undergoing percutaneous coronary intervention. Patients & methods: Clinical events including in-hospital, 1-month and 1-year mortality were compared between three groups based on HbA1c levels of patients (I: ≤5.6%, II: 5.7-6.4%, III: ≥6.5%). Results: Among 165 diabetic individuals, patients with abnormal HbA1c levels (≥6.5%) experienced significantly higher hospitalization days (7.65 ± 1.64 days) compared with those with normal HbA1c (4.94 ± 0.97 days) (p < 0.0001). In-hospital mortality was significantly higher in group III (14.5%) and II (5.5%) compared with group I (0%) (p = 0.008). Conclusion: HbA1c levels may be a reliable predictor of short-term clinical events in diabetic patients.
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接受经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死患者的血红蛋白 A1c 水平与 1 年死亡率。
背景:在这项研究中,我们调查了接受经皮冠状动脉介入治疗的糖尿病患者中,不同的血红蛋白 A1c (HbA1c) 水平是否与不同的短期和 1 年死亡率有关。患者与方法:根据患者的 HbA1c 水平(I:≤5.6%;II:5.7-6.4%;III:≥6.5%),比较三组患者的临床事件,包括院内、1 个月和 1 年死亡率。结果在 165 名糖尿病患者中,HbA1c 水平异常(≥6.5%)的患者住院天数(7.65 ± 1.64 天)明显高于 HbA1c 正常的患者(4.94 ± 0.97 天)(P < 0.0001)。与第一组(0%)相比,第三组(14.5%)和第二组(5.5%)的住院死亡率明显更高(p = 0.008)。结论HbA1c 水平可能是糖尿病患者短期临床事件的可靠预测指标。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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