A Review on Mouth Dissolving Tablets

Sumit S. Mohite, Amarnath B. Munde, Jai A. Lagad, Trupti Shaha
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引用次数: 6

Abstract

Traditional dosage forms, such as pills and capsules, are now used to treat conditions like dysphagia, which increases the risk of non-compliance and makes therapy ineffective. Mouth dissolving tablets were created to solve the problems associated with traditional dosage forms. They offer good hardness, dose uniformity, and convenience of administration. For pediatric, geriatric, and travel patients, they are the preferred dose form. Providing the MDTs with enough hardness, integrity, and disintegration speed without the requirement for water was the aim of their development. For fast-dissolving tablets to dissolve in saliva quickly, water is not needed. Some tablets are designed to dissolve in saliva very quickly in just a few seconds and are therefore referred to as "fast-dissolving" tablets. Because they contain substances that accelerate the pace at which the tablet dissolves in the mouth otherwise, it might take up to a minute some tablets are best referred to as fast-disintegrating tablets. This tablet type is designed to make it possible to administer an oral solid dose form in situations when no water or fluids are taken. These tablets typically dissolve in less than 60 seconds when dissolved in saliva.
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口腔溶解片综述
现在,人们使用药丸和胶囊等传统剂型来治疗吞咽困难等疾病,这增加了患者不遵医嘱的风险,并导致治疗效果不佳。口腔溶解片就是为了解决与传统剂型相关的问题而诞生的。它们具有良好的硬度、剂量均匀性和给药便利性。对于儿科、老年病和旅行病人来说,口腔溶解片是首选剂型。开发 MDT 的目的是使其具有足够的硬度、完整性和崩解速度,而无需用水。要使速溶片剂在唾液中快速溶解,就不需要水。有些药片可以在几秒钟内迅速溶解在唾液中,因此被称为 "速溶 "药片。有些药片含有能加快药片在口腔中溶解速度的物质,否则可能需要长达一分钟的时间,因此这些药片被称为快速崩解片。设计这种片剂的目的是为了在不喝水或液体的情况下给药。这些药片溶解于唾液后,通常在 60 秒内即可溶解。
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