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Study of Intermolecular Interaction by Ultrasonic Measurements of 1-Butanol-Pyridine and Toluene-Pyridine at 303.15 To 323.15 K and Statistical Analysis of Liquid State Theories 在 303.15 至 323.15 K 温度下通过超声波测量 1-丁醇-吡啶和甲苯-吡啶来研究分子间相互作用以及液态理论的统计分析
Pub Date : 2024-07-21 DOI: 10.32628/ijsrst241146
Samir M. Bagade, Ankush W Wakode
The experimental parameters measured in binary liquid mixtures, such as ultrasonic velocity (u) and density (ρ) containing 1-butanol-pyridine and toluene-pyridine across the full range of composition at different temperatures 303.15K to 323.15K, are used to evaluate acoustical parameters. The parameters are also theoretically calculated by using the Jacobson free length theory (flt) and Kalidoss revised free length theory (rflt). The statistical analysis of the liquid state theories has been done by applying chi-square (χ2) test. The findings were explained in terms of the liquid state theories that applied to binary liquid mixes as well as molecular interaction.
在含有 1-丁醇-吡啶和甲苯-吡啶的二元液体混合物中测得的实验参数,如在 303.15K 至 323.15K 不同温度下的全成分范围内的超声波速度 (u) 和密度 (ρ),用于评估声学参数。这些参数还通过雅各布森自由长度理论(flt)和卡利多斯修正自由长度理论(rflt)进行了理论计算。液态理论的统计分析采用了卡方检验(χ2)。研究结果从适用于二元液体混合物的液态理论以及分子相互作用的角度进行了解释。
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引用次数: 0
Biodistribution and Absorption of Radiopharmaceutical 99mTc MDP in Various Bones of Lung Cancer Patients Using SPECT/CT Modalities 利用 SPECT/CT 模式研究放射性药物 99mTc MDP 在肺癌患者不同骨骼中的生物分布和吸收情况
Pub Date : 2024-07-21 DOI: 10.32628/ijsrst241147
Salman Alfarizi, Wahyu Setia Budi, Zaenal Arifin, M. Roeslan Abdul Gani, Junan Imaniar Pribadi
Lung-to-bone cancer metastasis frequently involves bone lesions, particularly in the vertebrae. A bone scan using the radiopharmaceutical 99mTc MDP is a common diagnostic tool for detecting advanced metastases. This research aimed to determine the conversion factor of count rate to unit activity, assess the range of source activity in bones with and without lesions, and analyze the relationship between lung cancer metastasis and radiopharmaceutical activity in various bones. The study involved 28 patients. Procedures included phantom manufacturing, determining the depth of Antero Posterior (AP) and Postero Anterior (PA) position bones, converting count rates to activity units, and assessing 99mTc MDP biodistribution in bones. Results indicated that the conversion factor of count rate to activity units in AP and PA positions for lumbar vertebrae, costa vera, ilium, and sacrum were (〖13.2×10〗^(-4); 4.9〖×10〗^(-4)) mCi/cps; (4.0〖×10〗^(-4); 4.4〖×10〗^(-4)) mCi/cps; (4.0〖×10〗^(-4); 4.9〖×10〗^(-4)) mCi/cps; and (〖12.2×10〗^(-4); 〖4.5×10〗^(-4)) mCi/cps. In addition, there is a range of source activity values and percentage of activity in the bones (lumbar vertebrae; costa vera; ilium; and sacrum), namely (0.019-0.053) mCi and (0.107-0.498)%; (0.020-0.045) mCi and (0.139-0.338)%; (0.024-0.066) mCi and (0.128-0.551)%; and (0.012-0.028) mCi and (0.078-0.264)%. Furthermore, there is a range of source activity values in the lesion-indicated bone (lumbar vertebrae; costa vera; ilium; and sacrum), namely (0.038-0.053) mCi; (0.024-0.045) mCi; (0.033-0.066) mCi; and (0.017-0.028) mCi. The relationship between lung cancer metastasis to various bones studied and the range of radiopharmaceutical activity values obtained is moderately positive.
肺癌骨转移经常涉及骨病变,尤其是脊椎骨。使用放射性药物 99mTc MDP 进行骨扫描是检测晚期转移灶的常用诊断工具。这项研究旨在确定计数率与单位放射性活度的换算系数,评估有病变和无病变骨骼中放射源放射性活度的范围,并分析肺癌转移与不同骨骼中放射性活度之间的关系。这项研究涉及 28 名患者。程序包括制作模型、确定前方(AP)和后方(PA)位置骨骼的深度、将计数率转换为放射性活度单位,以及评估骨骼中 99mTc MDP 的生物分布。结果表明,腰椎、脊柱、髂骨和骶骨在 AP 和 PA 位置的计数率与活性单位的转换系数分别为〖13.2×10〗^(-4);4.9〖×10〗^(-4))mCi/cps;(4.0〖×10〗^(-4);4.4〖×10〗^(-4))mCi/cps;(4.0〖×10〗^(-4);4.9〖×10〗^(-4))mCi/cps;以及(〖12.2×10〗^(-4);〖4.5×10〗^(-4))mCi/cps。此外,骨骼(腰椎、脊柱、髂骨和骶骨)中的源活度值和活度百分比也有一定范围,即(0.此外,放射性活度源值的范围还包括:(0.024-0.066) mCi 和 (0.128-0.551) %;以及 (0.012-0.028) mCi 和 (0.078-0.264) %。此外,病变指示骨(腰椎、脊柱、髂骨和骶骨)中的放射源活性值也有不同,分别为(0.038-0.053)毫西里、(0.024-0.045)毫西里、(0.033-0.066)毫西里和(0.017-0.028)毫西里。肺癌转移到所研究的各种骨骼与所获得的放射性药物活性值范围之间的关系呈中度正相关。
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引用次数: 0
Analysis of Radiation Dose Rate and Evaluation of Whole Body Scan SPECT/CT Images in Thyroid Carcinoma Radioablation Patients Using Radioisotope 131I 使用放射性同位素 131I 对甲状腺癌放射性消融患者进行辐射剂量率分析和全身扫描 SPECT/CT 图像评估
Pub Date : 2024-07-21 DOI: 10.32628/ijsrst24114115
Indah Maulidina, Zaenal Arifin, Zaenul Muhlisin, M. Roeslan Abdul Gani, Junan Imaniar Pribadi
The incidence rate of thyroid carcinoma shows an increasing trend from year to year. One method for treating thyroid carcinoma is radioablation therapy using 131I. The use of 131I must be carried out in accordance with radiation safety regulations to avoid undesirable radiation dose rates. Therefore, research was conducted to analyze the radiation dose rate emitted by patients, obtain the relationship between body mass index (BMI) and the emitted dose rate, and evaluate whole body scan images of Single-Photon Emission Computed Tomography (SPECT/CT) of thyroid carcinoma radioablation patients. The research was carried out by measuring the patient's radiation dose rate using a surveymeter. The sample used was 53 patients who met the inclusion criteria and were not included in the exclusion criteria. The patient is isolated until it is safe to leave the hospital, then the therapy is evaluated by means of a whole body scan using SPECT/CT. Region of Interest (ROI) was carried out on the thyroid, stomach, liver, large intestine and bladder. On the third day the patient's dose rate value was below 70 μSv/h so that the patient could go home safely in accordance with radiation protection regulations. The average dose rate value for obese patients was higher compared to patients with low, normal and excess BMI. The high organ radiation count value for whole body SPECT/CT scan patients is caused by several factors such as the absorption of 131I by organs and the buildup of radioisotopes in organs.
甲状腺癌的发病率呈逐年上升趋势。治疗甲状腺癌的方法之一是使用 131I 进行放射性消融治疗。131I 的使用必须符合辐射安全法规,以避免不良辐射剂量率。因此,研究人员分析了患者的辐射剂量率,获得了身体质量指数(BMI)与辐射剂量率之间的关系,并对甲状腺癌放射消融患者的单光子发射计算机断层扫描(SPECT/CT)全身扫描图像进行了评估。研究是通过测量仪测量患者的辐射剂量率进行的。所用样本为 53 名符合纳入标准且未被纳入排除标准的患者。患者被隔离直至可以安全离开医院,然后通过 SPECT/CT 全身扫描对治疗进行评估。对甲状腺、胃、肝、大肠和膀胱进行感兴趣区(ROI)扫描。第三天,患者的剂量率值低于 70 μSv/h,因此患者可以按照辐射防护规定安全回家。与低体重指数、正常体重指数和超重体重指数患者相比,肥胖患者的平均剂量率值更高。全身 SPECT/CT 扫描患者的器官辐射计数值较高是由多个因素造成的,如器官对 131I 的吸收和放射性同位素在器官中的积聚。
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引用次数: 0
Review about Organic-Inorganic Perovskite Single Crystal : Synthesis Methods, Properties and Applications 有机-无机 Perovskite Single Crystal : Synthesis Methods, Properties and Applications "相关评论
Pub Date : 2024-07-15 DOI: 10.32628/ijsrst241142
Monik N. Maisuriya, Priyanka Desai
Due to their easy synthesis and exceptional optoelectronic characteristics, such as their long carrier diffusion length, high carrier mobility, low trap density, and tuneable absorption edge ranging from ultraviolet (UV) to near-infrared (NIR), perovskite single crystals have attracted a lot of attention in recent years. These properties have the potential to be used in solar cells, photo-detectors (PDs), lasers, and other devices. In this review provides detailed information about the synthesis methods and applications of perovskite single crystals.
由于其易于合成且具有特殊的光电特性,如长载流子扩散长度、高载流子迁移率、低阱密度以及从紫外(UV)到近红外(NIR)的可调吸收边,近年来,过氧化物单晶备受关注。这些特性有望用于太阳能电池、光电探测器(PD)、激光器和其他设备。本综述详细介绍了包光体单晶的合成方法和应用。
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引用次数: 0
Radiotherapy 3D Isodosezones Graphical Optimization for Hyperfractionated Treatment Planning in Lung and Prostate Tumors with Bed Pareto-Multiobjective Model Dataset 利用床边帕累托多目标模型数据集进行肺癌和前列腺肿瘤超分割治疗计划的放疗三维等剂量区图形优化
Pub Date : 2024-07-13 DOI: 10.32628/ijsrst24114105
Francisco Casesnoves
In a recent contributions, [102], 3D imaging-processing Isodosezones [ Casesnoves, 2022 ], delimited by 3D Isodoselines were explained in lung cancer and other tumor types, such a sprostate. The radiotherapy model applied was the classical BED one algorithm. Modern biological-model-based Treatment Planning Optimization can get objective improvements by using Isodosezones/lines when selecting the optimal dose delivery/schedule for any personalized treatment. Improved programming, [ Casesnoves, May 7th, 2024 ], and engineered software was developed for numerical hyperfractionated 3D TPO lung and prostate cancer imaging-processing database. Mathematical algorithms are detailed. A series of graphics results obtained with the 3D Imaging-Isodosezones Pareto-Multiobjective Optimization programming is shown and detailed. Applications in radiotherapy medical physics are subsequently briefed. An illustrative review of previous cancer studies with 3DInverse and 3DGraphical Optimization is included.
最近的一篇论文[102]解释了肺癌和其他肿瘤类型(如前列腺癌)中由三维等剂量线划定的三维成像处理等剂量区[Casesnoves, 2022]。应用的放疗模型是经典的 BED one 算法。在为任何个性化治疗选择最佳剂量给药/计划时,基于生物模型的现代治疗计划优化可以通过使用等剂量区/线获得客观改进。2024年5月7日,[Casesnoves],改进的编程和工程软件被开发用于数值超分割三维TPO肺癌和前列腺癌成像处理数据库。详细介绍了数学算法。详细介绍了三维成像-等碘区帕累托多目标优化编程获得的一系列图形结果。随后简要介绍了在放射治疗医学物理学中的应用。此外,还回顾了之前使用 3DInverse 和 3DGraphical Optimization 进行的癌症研究。
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引用次数: 0
High Throughput DWT Architecture for Signal Processing 用于信号处理的高吞吐量 DWT 架构
Pub Date : 2024-07-13 DOI: 10.32628/ijsrst24114109
N B V V S S Mani Manjari, Dr. S V R K RAO
The Discrete Wavelet Transform (DWT) is essential in signal processing systems because it is capable of accurately recording both frequency and time-domain features. Nevertheless, the computational intricacy of DWT presents notable obstacles to processing in real-time, particularly in circumstances with large data consumption. This study presents a VLSI technology designed to accelerate DWT processing utilizing CMOS gates. The goal is to improve throughput while maintaining area efficiency. The architecture utilizes parallelism and pipelining techniques to take use of the fundamental redundancy in DWT processing. We focus on creating customized processing units developed specifically for performing Discrete Wavelet Transform (DWT) operations. These units are tuned to make the best possible usage of CMOS gate capabilities. The proposed architectural is implemented using Cadence virtuoso software with 45 nm design. It is evaluated based on its area, power consumption, and latency. The current techniques employed to assess the proposed design include the utilization of the Radix-2 technique for FIR filter design, as well as the employment of look-up-table carry select adder (LCSLA), Vedic design (VD), and carry look-ahead adder (CLA). The developed system design has an area of 1764 um2, which makes it smaller than that of conventional approaches.
离散小波变换(DWT)在信号处理系统中至关重要,因为它能够准确记录频域和时域特征。然而,DWT 的计算复杂性给实时处理带来了明显的障碍,尤其是在数据消耗量较大的情况下。本研究提出了一种 VLSI 技术,旨在利用 CMOS 栅极加速 DWT 处理。其目标是在保持面积效率的同时提高吞吐量。该架构利用并行和流水线技术来利用 DWT 处理中的基本冗余。我们的重点是创建专门用于执行离散小波变换 (DWT) 操作的定制处理单元。我们对这些单元进行了调整,以最大限度地利用 CMOS 栅极能力。所提出的架构使用 Cadence virtuoso 软件实现,采用 45 纳米设计。根据其面积、功耗和延迟对其进行了评估。评估拟议设计所采用的当前技术包括利用 Radix-2 技术进行 FIR 滤波器设计,以及采用查找表携带选择加法器(LCSLA)、吠陀设计(VD)和携带前瞻加法器(CLA)。所开发的系统设计面积为 1764 um2,小于传统方法的面积。
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引用次数: 0
Machine Learning Based Liver Cirrhosis Detection Using Different Algorithm : A Review 使用不同算法进行基于机器学习的肝硬化检测:综述
Pub Date : 2024-07-13 DOI: 10.32628/ijsrst2411353
Priyal Jain, Prakash Saxena
Cirrhosis of the liver, a chronic hepatic condition marked by fibrosis and impaired functionality, poses substantial clinical difficulties worldwide. This comprehensive research review delves deeply into the study of liver cirrhosis, including its etiology, diagnosis, various treatment modalities, and prognosis. Various etiological variables, including conditions such as viral hepatitis, non-alcoholic fatty liver disease, and persistent alcohol consumption, contribute to the expansion of this syndrome via distinct mechanisms. Utilizing advanced methods such as transient elastography is crucial for achieving a precise diagnosis, which depends on a combination of clinical judgment, imaging tests, and histological examination. Various therapeutic approaches may be used based on the harshness of the patients state, including liver transplantation, pharmacotherapy, endoscopic interventions, and modifications in lifestyle. The prediction of the illness is contingent upon the severity of the cirrhosis and the resulting complications. Severe cirrhosis is correlated with an increased likelihood of death, in addition to the development of hepatocellular cancer. Healthcare professionals must collaborate across several disciplines to provide optimal care to their patients.
肝硬化是一种以肝纤维化和功能受损为特征的慢性肝病,给全世界的临床治疗带来了巨大困难。这篇综合研究综述深入探讨了肝硬化的病因、诊断、各种治疗方法和预后。各种病因变量,包括病毒性肝炎、非酒精性脂肪肝和长期饮酒等情况,通过不同的机制导致了这种综合征的扩大。利用瞬态弹性成像等先进方法进行精确诊断至关重要,而这取决于临床判断、成像检测和组织学检查的综合结果。根据患者病情的严重程度,可采用各种治疗方法,包括肝移植、药物治疗、内窥镜干预和改变生活方式。对病情的预测取决于肝硬化的严重程度及其引起的并发症。严重的肝硬化除了会导致肝细胞癌外,还会增加死亡的可能性。医护人员必须跨学科合作,为患者提供最佳护理。
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引用次数: 0
Identification and Antimicrobial Susceptibility Testing of Staphylococcus Aureus from Clinical Samples of Tertiary Care Centre, North India 印度北部三级医疗中心临床样本中金黄色葡萄球菌的鉴定和抗菌药敏感性测试
Pub Date : 2024-07-08 DOI: 10.32628/ijsrst24114104
Ved Prakash Sharma
Staphylococci are contributors of the Micrococcaceae family. Staphylococcus aureus is the most common type of bacteria which causes infections in the humans. They are classically taken into consideration extracellular, pyogenic pathogens due to their capacity to set off abscess formation. The microorganisms are non-motile and generally tend to develop in clusters. They are extraordinarily hardy and may continue to exist for extended durations of time on environmental surfaces. Staphylococci are identified in medical samples with the aid of using Gram stain and their function morphology – Gram positive cocci in grape-like clusters. They shape spherical frequently beta-hemolytic colonies on agar. It is characterized by the presence of the bacteria in different samples collected from different departments and the use of different antibiotic drugs and other medicines have increased the rate of infections. Some of the other risk factors includes the advanced ages and hospitalization. Staphylococcus aureus can be of different types like MRSA, MSSA, VRSA etc. Staphylococcus can cause infections in different ages it can infect child also or adult also. Different types of samples of Staphylococcus aureus can be identified using MALDI-TOF, MICROSCAN and BD PHOENIX and their interpretation of the antimicrobial susceptibility test can be given. Staphylococcus aureus is a major bacterial human pathogen that causes a wide variety of harmful diseases to the clinical manifestations. Infections caused by this bacterium are commonboth in community as well as hospital settings and treatment of the diseases caused by this remains challenging to manage. Because due to the emergence of its multi-drug resistant strainssuch as MRSA. Different drugs were used like Amp/Sulbactam, Ampicilin, Ceftriaxone, Ciprofloxacin, Clindamycin, Daptomycin, Erythomycin, Linezolid, Oxacillin, Rifampin, Synercid, Tetracycline, Teicoplanin, Vancomycin, Penicillin. The antimicrobial susceptibility test was done and their resistance percentage is calculated.
葡萄球菌属于微球菌科。金黄色葡萄球菌是导致人类感染的最常见细菌类型。它们通常被视为细胞外化脓性病原体,因为它们有能力引发脓肿形成。这种微生物不运动,一般倾向于集群发展。它们非常顽强,可在环境表面持续存在很长时间。借助革兰氏染色法和它们的功能形态--葡萄状成群的革兰氏阳性球菌--可以在医疗样本中识别葡萄球菌。它们在琼脂上经常形成球形的β-溶血性菌落。它的特点是从不同科室收集的不同样本中发现的细菌,不同抗生素药物和其他药物的使用增加了感染率。其他一些风险因素包括高龄和住院。金黄色葡萄球菌可分为 MRSA、MSSA、VRSA 等不同类型。金黄色葡萄球菌可引起不同年龄段的感染,它既可以感染儿童,也可以感染成人。可以使用 MALDI-TOF、MICROSCAN 和 BD PHOENIX 对不同类型的金黄色葡萄球菌样本进行鉴定,并对其进行抗菌药物敏感性检测。金黄色葡萄球菌是一种主要的人类细菌性病原体,可引起多种临床表现的有害疾病。由这种细菌引起的感染在社区和医院环境中都很常见,而治疗这种细菌引起的疾病仍然具有挑战性。由于出现了多重耐药菌株,如 MRSA。使用了不同的药物,如安培/舒巴坦、氨苄西林、头孢曲松、环丙沙星、克林霉素、达托霉素、红霉素、利奈唑胺、氧西林、利福平、西奈德、四环素、替考拉宁、万古霉素、青霉素。进行了抗菌药敏感性测试,并计算了抗药性百分比。
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引用次数: 0
Evaluation of the Antimicrobial Activities of Some Metal (Ii) Pyrimethamine Complexes 评估一些金属 (Ii) 嘧霉胺络合物的抗菌活性
Pub Date : 2024-07-08 DOI: 10.32628/ijsrst24114106
Tasiu Dahiru, Bilya Abdu, Dauda Hassan Lamuntani
The research work focused on the synthesis and antimicrobial studies of complexes of Manganese (II), Cobalt (II) and Nickel (II) with 5-(-4-Chlorophenyl)-6ethylpyrimidinediamiane (pyrimethamine) which serve as ligand. The complexes were prepared by direct combination of aqueous solution of the metal ions with the solution of pyrimethamine drug in methanol. The metal complexes were then characterized by conductance measurement, determination of decomposition temperature and infrared spectral analysis. The spectral analysis shows the ligand as bidental and coordinates to the metals through the nitrogen atom of the respective amine groups. Elemental analysis shows that all the complexes have octahedral configuration [ML2CL2], Where L = Ligand and M = metal. Molar conductance measurement and decomposition temperature analysis indicate that all the complexes are stable, non-electrolytes chelates. Antimicrobial evaluation of the complexes shows varied degree of inhibitory effect against some bacterial and fungal isolates; staphylococcus aureus, escheria coli, salmonella typhi and mucor spp and Rhizopus spp. However the antimicrobial activity of Mn(II) complex was found to be greater than cobalt (II) and Nickel (II) Complexes.
研究工作的重点是锰 (II)、钴 (II) 和镍 (II) 与作为配体的 5-(-4-氯苯基)-6-乙基嘧啶二脒 (嘧霉胺) 复合物的合成和抗菌研究。这些配合物是通过将金属离子水溶液与甲醇中的嘧霉胺药物溶液直接结合而制备的。然后通过电导测量、分解温度测定和红外光谱分析对金属配合物进行了表征。光谱分析显示,配体为双价配体,通过各自胺基团的氮原子与金属配位。元素分析表明,所有配合物都具有八面体构型 [ML2CL2],其中 L = 配体,M = 金属。摩尔电导测量和分解温度分析表明,所有配合物都是稳定的非电解质螯合物。复合物的抗菌评估表明,它们对一些细菌和真菌分离物(金黄色葡萄球菌、大肠杆菌、伤寒沙门氏菌、粘菌属和根霉属)具有不同程度的抑制作用。
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引用次数: 0
Analysis of Competitiveness and Efficiency the Export of Essential Oils from Indonesia 印度尼西亚精油出口的竞争力和效率分析
Pub Date : 2024-07-08 DOI: 10.32628/ijsrst24114103
Rahmatun Nisa, Tony Irawan, Widyastutik
This study analyzes the competitiveness, efficiency, and factors influencing Indonesia's essential oils exports using the Stochastic Frontier Gravity Model (SFGM). The main variables examined include Gross Domestic Product (GDP), Revealed Comparative Advantage (RCA), population, exchange rate, and geographical distance. The findings indicate that Indonesian essential oils are highly competitive in international markets, particularly in France, Spain, and Switzerland. Significant factors affecting export value include the real GDP of the destination country, RCA, population, exchange rate, and geographical distance. Additionally, inefficiency factors are influenced by area, language, business freedom, investment freedom, and financial freedom. Export efficiency is categorized into five levels. This study provides empirical insights into the impact of economic and non-economic factors on the export performance of Indonesian essential oils, offering valuable implications for policymakers and industry stakeholders to enhance global competitiveness and efficiency.
本研究利用随机前沿引力模型(SFGM)分析了印度尼西亚精油出口的竞争力、效率和影响因素。研究的主要变量包括国内生产总值(GDP)、显性比较优势(RCA)、人口、汇率和地理距离。研究结果表明,印尼精油在国际市场上具有很强的竞争力,尤其是在法国、西班牙和瑞士。影响出口额的重要因素包括目的地国的实际国内生产总值、比较优势、人口、汇率和地理距离。此外,低效率因素还受到地区、语言、商业自由度、投资自由度和金融自由度的影响。出口效率分为五个等级。本研究提供了经济和非经济因素对印尼精油出口绩效影响的实证见解,为政策制定者和行业利益相关者提高全球竞争力和效率提供了有价值的启示。
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引用次数: 0
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International Journal of Scientific Research in Science and Technology
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