CANCER: ETIOLOGY, CONTROL AND NUTRITION

Abstract

Cancer is the leading cause of death in the world; and cancer treatments are becoming more expensive and there are not resources available in any institution or government for their cure. In 2020, there were 19.3 million new cases and around 10 million deaths and 28.4 million cases are expected by 2024. The most common types of cancer are breast, lung, colon and rectum and prostate; approximately 30% are due to tobacco use, alcohol consumption, low fruit and vegetable intake, and lack of physical activity; as well as infections caused by hepatitis viruses or human papillomaviruses. Cancer in children and adolescents is one of the leading causes of death in the worldwide. Each year, more than 400,000 children are diagnosed globally. In children, leukemias are more common, then brain tumors, and then lymphomas. This makes it a public health problem in Mexico and the worldwide. Amino acids stimulate cell growth and development cellular. Polyamines are the integrated part of the cellular and genetic metabolism and help in transcription, translocation, signaling and post-translational modications. Polyamines binding to RNA leads to structural changes which stimulate and increase the protein synthesis along the amino acids may inuence the conditions of various diseases. Several diseases can be controlled to a higher extend via maintaining the metabolism of amino acids and polyamines. On the other hand, a controlled diet is a way to maintain the level of amino acids and polyamines in the body. Present review highlights to etiology of cancer, also discusses functions and metabolism of polyamines in human and also highlights the nutritional role of amino acids and polyamines in the prevention and control of various diseases.