Objectives: The Superior laryngeal artery (SLA) is the dominant arterial supply of the laryngeal muscles, mucosa and glands. Normally it is a branch of Superior thyroid artery (STA). Knowledge of variation in origin of SLA is important to achieve bloodless eld of surgery during partial laryngectomy, radical neck dissection and other neck surgeries. 30 Materials and Method: formalin xed human cadavers (60 hemi necks) of both the sex from department of anatomy BGS GIMS and BMC&RI have been dissected to study the origin of SLA. In 75% cases SLA originated from STA, in 11.6% cases SLA originated from Ex Result: ternal carotid artery, in 8.3% cases SLA originated from common carotid artery and in 5% cases it originated from carotid bifurcation. Precise anatomical Conclusion: knowledge of variations in the origin of SLA is essential for minimizing complications during laryngeal surgeries, laryngeal transplantation and for selective intra- arterial chemotherapy for laryngeal cancers.
{"title":"STUDY OF VARIATION IN ORIGIN OF SUPERIOR LARYNGEAL ARTERY AND ITS CLINICAL SIGNIFICANCE","authors":"V. K S, Ashok K. R","doi":"10.36106/ijar/8302350","DOIUrl":"https://doi.org/10.36106/ijar/8302350","url":null,"abstract":"Objectives: The Superior laryngeal artery (SLA) is the dominant arterial supply of the laryngeal muscles, mucosa and\u0000glands. Normally it is a branch of Superior thyroid artery (STA). Knowledge of variation in origin of SLA is important to\u0000achieve bloodless eld of surgery during partial laryngectomy, radical neck dissection and other neck surgeries. 30 Materials and Method:\u0000formalin xed human cadavers (60 hemi necks) of both the sex from department of anatomy BGS GIMS and BMC&RI have been dissected to\u0000study the origin of SLA. In 75% cases SLA originated from STA, in 11.6% cases SLA originated from Ex Result: ternal carotid artery, in 8.3%\u0000cases SLA originated from common carotid artery and in 5% cases it originated from carotid bifurcation. Precise anatomical Conclusion:\u0000knowledge of variations in the origin of SLA is essential for minimizing complications during laryngeal surgeries, laryngeal transplantation and\u0000for selective intra- arterial chemotherapy for laryngeal cancers.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To evaluate and identify the relevance of foundation course in the curriculum of rst year medical students of ASMC, Firozabad. A cross-sectional study was conducted on 78 (40 males and 38 females) rst year Study Design: students of ASMC, Firozabad (UP). A questionnaire comprising of skill module, community orientation module, ethics module and competence skill module were given to students on 1st September 2023 and again on 30th September 2023. The data so obtained was analysed using 3 point Likert scale. A questionnaire with 4 modules consisting of skill module, ethics module, community o Materials and Methodology: rientation module and language and computer skill module was prepared and circulated in class. 78 students (40 males and 38 females) were enrolled for the study. All data was collected and compiled on Microsoft Excel Worksheet. Foundation course was foun Results: Conclusion: d to be benecial to the students to get introduced to the medical eld and to get acclimatized to the totally new journey of becoming an IMG or physician of 1st contact.
{"title":"PERSPECTIVE OF FOUNDATION COURSE BY FIRST YEAR STUDENTS OF ASMC, FIROZABAD","authors":"Priyanka Gupta, Nita Garg, Himanshu Soni","doi":"10.36106/ijar/0203469","DOIUrl":"https://doi.org/10.36106/ijar/0203469","url":null,"abstract":"Aim: To evaluate and identify the relevance of foundation course in the curriculum of rst year medical students of\u0000ASMC, Firozabad. A cross-sectional study was conducted on 78 (40 males and 38 females) rst year Study Design:\u0000students of ASMC, Firozabad (UP). A questionnaire comprising of skill module, community orientation module, ethics module and competence\u0000skill module were given to students on 1st September 2023 and again on 30th September 2023. The data so obtained was analysed using 3 point\u0000Likert scale. A questionnaire with 4 modules consisting of skill module, ethics module, community o Materials and Methodology: rientation\u0000module and language and computer skill module was prepared and circulated in class. 78 students (40 males and 38 females) were enrolled for the\u0000study. All data was collected and compiled on Microsoft Excel Worksheet. Foundation course was foun Results: Conclusion: d to be benecial to\u0000the students to get introduced to the medical eld and to get acclimatized to the totally new journey of becoming an IMG or physician of 1st\u0000contact.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141040274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Chromoblastomycosis is a rare chronic fungal infection world wide.Madagascar remains the highest burden taker of this condition. In India it has been reported in the areas of western ghats more often , this case has been reported from South India with treatment received as cutaneous TB.The organism enters into skin following trauma or breach in skin. The case has been reported because of its rare occurrence and often misdiagnosed in clinical practice.
{"title":"A RARE CASE REPORT OF CHROMOBLASTOMYCOSIS WITH TUBERCULIN SKIN TEST POSITIVITY.","authors":"S K Atiya, Fawaaz Lateef","doi":"10.36106/ijar/6503729","DOIUrl":"https://doi.org/10.36106/ijar/6503729","url":null,"abstract":"Introduction: Chromoblastomycosis is a rare chronic fungal infection world wide.Madagascar remains the highest\u0000burden taker of this condition. In India it has been reported in the areas of western ghats more often , this case has been\u0000reported from South India with treatment received as cutaneous TB.The organism enters into skin following trauma or breach in skin. The case has\u0000been reported because of its rare occurrence and often misdiagnosed in clinical practice.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haemorrhoid poses a surgical challenge in the anorectal region causing considerable discomfort and psychological distress to the patient. With the advent of non-surgical interventions, such as infrared coagulation and bipolar diathermy, the frequency of haemorrhoidectomies has declined. This study aims to compare the efcacy of sclerotherapy and rubber band ligation in managing haemorrhoids, focusing on post-operative complications and recurrence. Over one and half years, 100 haemorrhoid patients aged 19 to 66 years were enrolled in this study from a peripheral medical college in West Bengal, India. Patients underwent either Barron's banding or sclerotherapy with 5% phenol in olive oil. Post-operative outcomes were addressed at intervals, including pain, bleeding and infection at one week, four weeks and six months. Results revealed a signicant reduction in post-operative pain in patients treated with Barron's band ligation compared to sclerotherapy (p<0.003 at one week and p<0.001 at one month). Additionally, fewer cases of wound infection were observed in the banding group. Recurrence rates were signicantly higher in the sclerotherapy group at six months (p=0.03).
{"title":"A COMPARATIVE STUDY OF BARRON'S BANDING VERSUS SCLEROTHERAPY IN THE MANAGEMENT OF HAEMORRHOIDS","authors":"Manas Mukul Mandal, Saptarshi Poddar","doi":"10.36106/ijar/1703967","DOIUrl":"https://doi.org/10.36106/ijar/1703967","url":null,"abstract":"Haemorrhoid poses a surgical challenge in the anorectal region causing considerable discomfort and psychological\u0000distress to the patient. With the advent of non-surgical interventions, such as infrared coagulation and bipolar diathermy,\u0000the frequency of haemorrhoidectomies has declined. This study aims to compare the efcacy of sclerotherapy and rubber band ligation in\u0000managing haemorrhoids, focusing on post-operative complications and recurrence. Over one and half years, 100 haemorrhoid patients aged 19 to\u000066 years were enrolled in this study from a peripheral medical college in West Bengal, India. Patients underwent either Barron's banding or\u0000sclerotherapy with 5% phenol in olive oil. Post-operative outcomes were addressed at intervals, including pain, bleeding and infection at one\u0000week, four weeks and six months. Results revealed a signicant reduction in post-operative pain in patients treated with Barron's band ligation\u0000compared to sclerotherapy (p<0.003 at one week and p<0.001 at one month). Additionally, fewer cases of wound infection were observed in the\u0000banding group. Recurrence rates were signicantly higher in the sclerotherapy group at six months (p=0.03).","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In our medical practice, we often encounter some patients who can be challenging to handle. Unfortunately, some of these patients, along with their friends and family members, may resort to violent or harmful behaviors toward doctors and paramedical staff during treatment. According to the World Health Organization, between 8% to 38% of healthcare workers have experienced physical violence at some point in their careers. (1)
{"title":"ANGRY PATIENT:","authors":"Dimple Jamkhandi","doi":"10.36106/ijar/1901976","DOIUrl":"https://doi.org/10.36106/ijar/1901976","url":null,"abstract":"In our medical practice, we often encounter some patients who can be\u0000challenging to handle. Unfortunately, some of these patients, along\u0000with their friends and family members, may resort to violent or harmful\u0000behaviors toward doctors and paramedical staff during treatment.\u0000According to the World Health Organization, between 8% to 38% of\u0000healthcare workers have experienced physical violence at some point\u0000in their careers. (1)","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141044037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amit Kumar, Manmeet Kaur Sodhi, Hanish Sharma, Richa Verma
Background: India being the land for almost one fth of the adolescents of the world, there is the need for gauging their physical, psychosocial and mental health status for their better upbringing. To assess the physical, Objectives: psychosocial and mental health of the young adolescents. A cross sectional study in 2 randomly select Methodology: ed schools of urban and rural areas located near Government Medical College (GMC), Amritsar was done in young adolescents of age group 10 to 14years. Adolescents of this age group attending OPD at Department of Pediatrics, GMC, Amritsar were also included. Out of 500 yo Result: ung adolescents interviewed, 22% often had doubts about their weight or height being less or more while almost one third of the participants (32.8%) sometimes felt so. 18.2% of the participants were often inuenced by the friends for bunking or teasing others while 12.8% felt the same only sometimes.19% of the respondents often had difculty in concentrating on the studies or work while it was experienced sometimes only by 26.2% of them. More than half of the participants (56.8%) didn't exercise at all or played any outdoor games. Adolescence bein Conclusion: g a very crucial stage of life, regular physical health checkups and counseling sessions are the need of the hour for their healthy and bright future.
{"title":"A STUDY TO SCREEN PHYSICAL HEALTH AND PSYCHOSOCIAL ISSUES AMONG YOUNG ADOLESCENTS IN AMRITSAR AND ITS ASSOCIATION WITH GENDER","authors":"Amit Kumar, Manmeet Kaur Sodhi, Hanish Sharma, Richa Verma","doi":"10.36106/ijar/8602495","DOIUrl":"https://doi.org/10.36106/ijar/8602495","url":null,"abstract":"Background: India being the land for almost one fth of the adolescents of the world, there is the need for gauging their\u0000physical, psychosocial and mental health status for their better upbringing. To assess the physical, Objectives:\u0000psychosocial and mental health of the young adolescents. A cross sectional study in 2 randomly select Methodology: ed schools of urban and rural\u0000areas located near Government Medical College (GMC), Amritsar was done in young adolescents of age group 10 to 14years. Adolescents of this\u0000age group attending OPD at Department of Pediatrics, GMC, Amritsar were also included. Out of 500 yo Result: ung adolescents interviewed,\u000022% often had doubts about their weight or height being less or more while almost one third of the participants (32.8%) sometimes felt so. 18.2%\u0000of the participants were often inuenced by the friends for bunking or teasing others while 12.8% felt the same only sometimes.19% of the\u0000respondents often had difculty in concentrating on the studies or work while it was experienced sometimes only by 26.2% of them. More than\u0000half of the participants (56.8%) didn't exercise at all or played any outdoor games. Adolescence bein Conclusion: g a very crucial stage of life,\u0000regular physical health checkups and counseling sessions are the need of the hour for their healthy and bright future.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurocutaneous melanosis (NCM) is known as a rare phakomatosis characterized by large or numerous pigmented congenital nevi associated with leptomeninges melanin containing deposits. NCM can be asymptomatic or present as variably severe and neurological impairment sometimes resulting in death. Prevalence is estimated at 1/50,000 –1/200000.The incidence of symptomatic NCM appears to be approximately a third to half of these
{"title":"NEUROCUTANEOUS MELANOSIS IN A NEWBORN – A CASE REPORT.","authors":"Dudekula Shalu BI, Shaik Irfani","doi":"10.36106/ijar/9801776","DOIUrl":"https://doi.org/10.36106/ijar/9801776","url":null,"abstract":"Neurocutaneous melanosis (NCM) is known as a rare phakomatosis\u0000characterized by large or numerous pigmented congenital nevi\u0000associated with leptomeninges melanin containing deposits. NCM can\u0000be asymptomatic or present as variably severe and neurological\u0000impairment sometimes resulting in death. Prevalence is estimated at\u00001/50,000 –1/200000.The incidence of symptomatic NCM appears to\u0000be approximately a third to half of these","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The theoretical framework and rationale of the study assess the most important scal parameter of the state of i.e., Public expenditure. As we know, aggregate of the expenditure of the state consists of Revenue expenditure and Capital expenditure, among which the largest share is contributed by Revenue expenditure. The paper highlights the composition, trend, percentage share of different components of expenditure to NSDP and growth of different components of expenditure in Odisha . The study is based on secondary source of data for the State from different government publications, Budget documents, Finance Accounts etc. The paper used different methodologies for analysis, which includes simple statistical techniques such as, ratio, percentage, and also Regression Analysis to estimate growth. In this regard models like, semi log, multiple regression, and correlation are used to analyse the time series data from 1980-81 to 2019-20 on expenditure component of state nances. The major results of the study is that amongst different components of the revenue expenditure, contribution of development expenditure has been signicantly increasing due to increasing share of the social services during the year 2019-20. Higher growth rates are found in case of revenue expenditure followed by non-development and lowest growth rates are exhibited by interest and servicing of debt. And the share of total revenue expenditure of the state was 12.3% in the NSDP during 1980-81, which raised to 22.4% in 2019- 20, this, is more signicantly due to the growth of development expenditure.
{"title":"COMPOSITION AND GROWTH OF PUBLIC EXPENDITURE IN ODISHA","authors":"Sunita Mishra","doi":"10.36106/ijar/9609491","DOIUrl":"https://doi.org/10.36106/ijar/9609491","url":null,"abstract":"The theoretical framework and rationale of the study assess the most important scal parameter of the state of i.e., Public\u0000expenditure. As we know, aggregate of the expenditure of the state consists of Revenue expenditure and Capital\u0000expenditure, among which the largest share is contributed by Revenue expenditure. The paper highlights the composition, trend, percentage share\u0000of different components of expenditure to NSDP and growth of different components of expenditure in Odisha . The study is based on secondary\u0000source of data for the State from different government publications, Budget documents, Finance Accounts etc. The paper used different\u0000methodologies for analysis, which includes simple statistical techniques such as, ratio, percentage, and also Regression Analysis to estimate\u0000growth. In this regard models like, semi log, multiple regression, and correlation are used to analyse the time series data from 1980-81 to 2019-20\u0000on expenditure component of state nances. The major results of the study is that amongst different components of the revenue expenditure,\u0000contribution of development expenditure has been signicantly increasing due to increasing share of the social services during the year 2019-20.\u0000Higher growth rates are found in case of revenue expenditure followed by non-development and lowest growth rates are exhibited by interest and\u0000servicing of debt. And the share of total revenue expenditure of the state was 12.3% in the NSDP during 1980-81, which raised to 22.4% in 2019-\u000020, this, is more signicantly due to the growth of development expenditure.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141054975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Srividya, A. Odayappan, R. Venkatesh, S. Kavitha
Purpose: To assess the reasons for visit amongst patients presenting to the glaucoma services and to assess their Knowledge, Attitude, Practices (KAP) in relation to COVID-19 and to assess the impact of COVID-19 on the glaucoma care provision. Design: Cross-sectional, observational study. Patients older than 18 years presenti Methods: ng to the glaucoma services at our tertiary eye centre either for the rst time or for follow-up between October and December 2020 - the immediate unlock period following the rst wave of COVID-19 pandemic were included. Data collected include the demographic details, visual acuity, intraocular pressure, examination ndings, nal diagnosis and suggested treatment. The patients' KAP was then assessed using a validated questionnaire. The distribution of the various glaucoma diagnoses was compared between 2020 (pandemic year) vs. 2019 (pre-pandemic year) Ov Results: erall, 246 patients were included. The main reasons for seeking care were headache (66.3%) followed by ocular surface symptoms like itching or irritation (25.2%) and pain (10.9%). 84.7% of follow-up patients reported that their visit to the hospital was delayed predominantly due to fear of getting infected (62.2%), paucity of public transport (48.4%) and lack of accompanying person (12.6%). There was signicantly greater proportion of new primary angle closure patients (40.3%, p=0.036) whereas those with primary open angle glaucoma had come for follow-up care (26.1 %, p=0.048). The mean KAP scores of the patients were 83.1%, 65.5% and 81.7% respectively. KAP in rel Conclusion: ation to COVID-19 was good and there was a greater proportion of patients with acute presentations.
{"title":"ASSESSMENT OF THE REASONS FOR PRESENTATION TO GLAUCOMA SERVICES DURING THE PANDEMIC AND THE KNOWLEDGE, ATTITUDE,PRACTICES (KAP) IN RELATION TO COVID-19","authors":"K. Srividya, A. Odayappan, R. Venkatesh, S. Kavitha","doi":"10.36106/ijar/5902200","DOIUrl":"https://doi.org/10.36106/ijar/5902200","url":null,"abstract":"Purpose: To assess the reasons for visit amongst patients presenting to the glaucoma services and to assess their\u0000Knowledge, Attitude, Practices (KAP) in relation to COVID-19 and to assess the impact of COVID-19 on the glaucoma\u0000care provision. Design: Cross-sectional, observational study. Patients older than 18 years presenti Methods: ng to the glaucoma services at our\u0000tertiary eye centre either for the rst time or for follow-up between October and December 2020 - the immediate unlock period following the rst\u0000wave of COVID-19 pandemic were included. Data collected include the demographic details, visual acuity, intraocular pressure, examination\u0000ndings, nal diagnosis and suggested treatment. The patients' KAP was then assessed using a validated questionnaire. The distribution of the\u0000various glaucoma diagnoses was compared between 2020 (pandemic year) vs. 2019 (pre-pandemic year) Ov Results: erall, 246 patients were\u0000included. The main reasons for seeking care were headache (66.3%) followed by ocular surface symptoms like itching or irritation (25.2%) and\u0000pain (10.9%). 84.7% of follow-up patients reported that their visit to the hospital was delayed predominantly due to fear of getting infected\u0000(62.2%), paucity of public transport (48.4%) and lack of accompanying person (12.6%). There was signicantly greater proportion of new\u0000primary angle closure patients (40.3%, p=0.036) whereas those with primary open angle glaucoma had come for follow-up care (26.1 %,\u0000p=0.048). The mean KAP scores of the patients were 83.1%, 65.5% and 81.7% respectively. KAP in rel Conclusion: ation to COVID-19 was\u0000good and there was a greater proportion of patients with acute presentations.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141040167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Papillary carcinoma breast is a rare type of breast malignancy accounting for only 0.5% of invasive breast cancers. According to the 2019 WHO Classication of Breast Tumors (5th edition), malignant papillary neoplasms comprise papillary ductal carcinoma in situ (DCIS), encapsulated papillary carcinoma (EPC), solid papillary carcinoma (SPC), and invasive papillary carcinoma (IPC). Histologic features of the tumor include cellular proliferations surrounding brovascular cores, with or without invasion. Conclusive differentiation between benign and malignant papillary breast lesions depends on demonstration of myoepithelial cells which may be difcult to discern on routine H & E stain. Therefore, IHC is a useful adjunct for evaluating the presence and distribution of myoepithelial cells in papillary neoplasms of the breast. Papillary carcinomas of breast are usually manifest the luminal A staining pattern (ER or PR positive; HER2 neu negative) along with negative staining for myoepithelial markers like p63 and calponin. In this case series, we report 5 cases of papillary neoplasms of breast reported at our institution, out of which one was a case of Encapsulated Papillary Carcinoma, while the other 4 were designated as Encapsulated Papillary Carcinoma with Invasion. Coexistent DCIS was seen in 3 cases, but due to the stringent criteria outlined in the latest WHO Classication, none of the tumors qualied to be designated as Invasive Papillary Carcinoma.
乳腺乳头状癌是一种罕见的乳腺恶性肿瘤，仅占浸润性乳腺癌的0.5%。根据2019年世界卫生组织乳腺肿瘤分类cation（第五版），恶性乳头状肿瘤包括乳腺导管原位癌（DCIS）、包裹性乳头状癌（EPC）、实性乳头状癌（SPC）和浸润性乳头状癌（IPC）。肿瘤的组织学特征包括围绕 血管核心的细胞增生，伴有或不伴有浸润。良性和恶性乳腺乳头状病变的最终鉴别取决于肌上皮细胞的显示，而常规的 H & E 染色可能难以。因此，IHC 是评估乳腺乳头状瘤中肌上皮细胞的存在和分布的有效辅助方法。乳腺乳头状癌通常表现为管腔A染色模式（ER或PR阳性；HER2neu阴性），同时肌上皮标记物（如p63和钙蛋白）染色阴性。在本病例系列中，我们报告了本院收治的 5 例乳腺乳头状瘤病例，其中一例为包裹性乳头状瘤，另外 4 例为包裹性乳头状瘤伴浸润。有3例并存DCIS，但由于最新的WHO分类cation中列出了严格的标准，这些肿瘤都不符合被定为浸润性乳头状癌的条件。
{"title":"HISTOMORPHOLOGY AND IMMUNOHISTOCHEMICAL STAINING PATTERNS IN PAPILLARY CARCINOMA BREAST: A SERIES OF 5 CASES","authors":"Ganguly S, Singh Bp, Thakur P","doi":"10.36106/ijar/1302187","DOIUrl":"https://doi.org/10.36106/ijar/1302187","url":null,"abstract":"Papillary carcinoma breast is a rare type of breast malignancy accounting for only 0.5% of invasive breast cancers.\u0000According to the 2019 WHO Classication of Breast Tumors (5th edition), malignant papillary neoplasms comprise\u0000papillary ductal carcinoma in situ (DCIS), encapsulated papillary carcinoma (EPC), solid papillary carcinoma (SPC), and invasive papillary\u0000carcinoma (IPC). Histologic features of the tumor include cellular proliferations surrounding brovascular cores, with or without invasion.\u0000Conclusive differentiation between benign and malignant papillary breast lesions depends on demonstration of myoepithelial cells which may be\u0000difcult to discern on routine H & E stain. Therefore, IHC is a useful adjunct for evaluating the presence and distribution of myoepithelial cells in\u0000papillary neoplasms of the breast. Papillary carcinomas of breast are usually manifest the luminal A staining pattern (ER or PR positive; HER2\u0000neu negative) along with negative staining for myoepithelial markers like p63 and calponin. In this case series, we report 5 cases of papillary\u0000neoplasms of breast reported at our institution, out of which one was a case of Encapsulated Papillary Carcinoma, while the other 4 were\u0000designated as Encapsulated Papillary Carcinoma with Invasion. Coexistent DCIS was seen in 3 cases, but due to the stringent criteria outlined in\u0000the latest WHO Classication, none of the tumors qualied to be designated as Invasive Papillary Carcinoma.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141042463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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