Estudio observacional retrospectivo sobre el sistema Minimed™ 780G en vida real: impacto de la configuración en la autocorrección y la omisión de bolus prandiales

Abstract

Introduction

The Medtronic MiniMed™ 780G (MM780G) system uses an algorithm that includes autocorrection bolus (AB) delivery. This study evaluates the impact of omitted meal boluses and the system settings, glucose target and active insulin time (AIT), on the AB.

Method

Retrospective observational study on data uploaded by all MiniMed™ 780G users in our healthcare area, obtained through the remote monitoring platform Care Connect, from April to August 2023. Downloads with a sensor usage time < 95% were excluded.

Results

235 downloads belonging to 235 users were analysed. AB delivery was significantly higher at 2 hours AIT (36.08 ± 13.17%) compared to the rest of settings (2.25 - 4 hours) (26.43 ± 13.2%) (p< 0.001). AB differences based on the glucose target were not found.

Patients with < 3 meal boluses per day had higher AB delivery (46.91 ± 19.00% vs 27.53 ± 11.54%) (p< 0.001) and had more unfavourable glucometric parameters (GMI 7.12 ± 0.45%, TIR 67.46 ± 12.89% vs GMI 6.78 ± 0.3%, TIR 76.51 ± 8.37%) (p< 0.001). However, the 2-hours AIT group presented similar TAR, TIR and GMI regardless of the number of meal boluses.

Conclusion

The fewer user-initiated boluses, the greater the autocorrection received. The active insulin time of 2 hours entails a more active autocorrection pattern that makes it possible to more effectively compensate for the omission of meal boluses without increasing hypoglycaemias.