A comparative study between single injection (corner pocket approach) and double injection costoclavicular block: A randomized parallel arm, non-inferiority trial

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Abstract

Background

Previous studies have shown that ultrasound guided costoclavicular block may require a double shot to provide adequate, rapid sensory and motor blockade. In this trial, we hypothesized that if the corner pocket approach (between axillary artery and median cord) is used instead of the central approach (at the midpoint of the 3 cords) when performing single-shot costoclavicular block, the onset of blockade would be non-inferior to the double-shot technique.

Method

Ninety patients undergoing upper limb surgery were randomized to 2 groups for ultrasound-guided costoclavicular block (CCB) at a tertiary hospital. One group received ultrasound guided single-shot CCB using the corner pocket approach and other received ultrasound guided double-shot – the first shot at the centre of the 3 cords and the second between the axillary artery and the median cord. An observer blinded to group assignment recorded blockade onset time (defined as the time required to achieve a minimal sensorimotor composite score of 14 out of 16 points).

Results

Of the 101 patients assessed for eligibility, 90 were recruited over period of 1 year (February 2022 to January 2023), with 45 in each group. Onset time was 22.1 ± 3.1 min in the single-shot group and 22.4 ± 2.9 min in the double-shot group. This difference was insignificant (P = .3).

Conclusion

Time to onset of blockade and full anaesthesia are similar in single-shot corner pocket CCB vs double-shot CCB. Further studies are required to determine the minimum effective volume of local anaesthetic required for the described technique.
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单次注射(角袋法)与双次注射肋锁关节阻滞的比较研究:随机平行臂、非劣效试验。
背景以前的研究表明,超声引导下的肋锁阻滞可能需要双针才能提供充分、快速的感觉和运动阻滞。在这项试验中,我们假设在进行单次肋锁关节阻滞时,如果使用角袋方法(腋动脉和正中脊髓之间)而不是中央方法(三条脊髓的中点),阻滞的开始时间将不会劣于双次技术。方法在一家三甲医院接受上肢手术的 90 名患者被随机分为两组,接受超声引导下的肋锁关节阻滞(CCB)。一组在超声引导下使用角袋法进行单次阻滞,另一组在超声引导下进行双次阻滞--第一次阻滞在三条脊索的中心,第二次阻滞在腋动脉和正中脊索之间。结果 在101名通过资格评估的患者中,有90人在一年内(2022年2月至2023年1月)被招募,每组45人。单发组的发病时间为 22.1 ± 3.1 分钟,双发组为 22.4 ± 2.9 分钟。结论单发角袋 CCB 与双发 CCB 的阻滞起效时间和完全麻醉时间相似。需要进一步研究以确定所述技术所需的最小有效局麻药量。
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