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Reassessing anaemia in gastrectomy: Diagnostic definitions and predictive value in the POWER 4 cohort. 重新评估胃切除术中的贫血:POWER 4队列的诊断定义和预测价值。
Pub Date : 2026-01-30 DOI: 10.1016/j.redare.2026.502020
J Ripolles-Melchor, A Abad-Motos, E Nieto Moreno, C Jerico, I Otero-Martínez, O Abdel-Lah Fernández, R García-Alvarez, M P Tormos-Pérez, A V Espinosa, C Aldecoa, A Abad-Gurumeta, M J Colomina, J A García-Erce

Background: Preoperative anaemia is a common finding in patients undergoing gastrectomy, and is frequently targeted in optimisation strategies. However, its independent association with postoperative complications remains unclear, and the prognostic value of redefining diagnostic thresholds has not been formally assessed.

Methods: This prospective substudy of the POWER 4 cohort included 742 patients undergoing elective gastrectomy for cancer. Anaemia was defined by WHO sex-specific thresholds (Hb <13 g/dL in men, <12 g/dL in women) and a universal threshold of <13 g/dL. Four subcohorts were analysed: A1 (WHO, full cohort), A2 (universal, full), B1 (WHO, untreated), B2 (universal, untreated). Multivariable logistic regression was used to assess associations with postoperative complications. Discrimination was evaluated using AUC, AIC/BIC, and Net Reclassification Improvement (NRI). Generalised additive models (GAMs) were used to explore continuous relationships between haemoglobin and risk.

Results: Anaemia prevalence was 38.0% with WHO thresholds and 52.4% with the universal threshold. In full-cohort models, anaemia was not independently associated with complications (A1 OR 0.92 [95% CI 0.60-1.41]; A2 OR 0.89 [0.59-1.36]). Model performance was similar (AUC 0.686). In untreated patients (n = 584), discrimination improved (B1 AUC 0.750; B2 AUC 0.743), but anaemia remained non-significant. NRI modestly favoured the universal threshold (A1/A2: 0.048; B1/B2: 0.072), with most reclassification occuring in intermediate risk groups. GAMs showed a smooth monotonic relationship without a clear inflection point.

Conclusion: Anaemia was not independently associated with postoperative complications. Redefining thresholds altered prevalence but did not improve prediction. Haemoglobin may be better used as part of an integrated perioperative risk assessment rather than a binary stratifier.

背景:术前贫血是胃切除术患者的常见发现,并且经常是优化策略的目标。然而,其与术后并发症的独立关系尚不清楚,重新定义诊断阈值的预后价值尚未得到正式评估。方法:POWER 4队列的前瞻性亚研究纳入了742例因癌症接受择期胃切除术的患者。贫血由WHO性别特异性阈值定义(Hb结果:WHO阈值的贫血患病率为38.0%,通用阈值为52.4%)。在全队列模型中,贫血与并发症没有独立关联(A1 OR 0.92 [95% CI 0.60-1.41]; A2 OR 0.89[0.59-1.36])。模型性能相似(AUC为0.686)。在未接受治疗的患者中(n = 584),区分有所改善(B1 AUC 0.750; B2 AUC 0.743),但贫血仍然不显著。NRI略微倾向于通用阈值(A1/A2: 0.048; B1/B2: 0.072),大多数重新分类发生在中等风险组。GAMs表现出平滑的单调关系,没有明显的拐点。结论:贫血与术后并发症无独立关系。重新定义阈值改变了患病率,但没有改善预测。血红蛋白可以更好地作为围手术期综合风险评估的一部分,而不是二元分层。
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引用次数: 0
Beyond the algorithm: Defending scientific integrity in the age of artificial intelligence. 超越算法:捍卫人工智能时代的科学完整性。
Pub Date : 2026-01-30 DOI: 10.1016/j.redare.2026.502002
R Casans-Francés, A Abad-Gurumeta
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引用次数: 0
Clinical prediction in treatment with 8% capsaicin patch for post-traumatic neuropathic pain: A critical perspective based on accumulated evidence. 8%辣椒素贴片治疗创伤后神经性疼痛的临床预测:基于积累证据的关键观点。
Pub Date : 2026-01-30 DOI: 10.1016/j.redare.2026.501992
A Alcántara Montero, P J Ibor Vidal
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引用次数: 0
Impact of preanesthetic consultation on presurgical anxiety assessed using the Amsterdam Preoperative Anxiety and Information Scale. 使用阿姆斯特丹术前焦虑和信息量表评估麻醉前会诊对术前焦虑的影响。
Pub Date : 2026-01-30 DOI: 10.1016/j.redare.2026.502005
M M Ureña Consuegra, Y V Llaverías Guzmán, L R Peralta Henson, S E Tejada Estrella, V M Cepeda Santos

Background: Preanesthesia consultation can be an effective tool for reducing anxiety scores in patients scheduled for elective surgery. Anxiety can cause perioperative complications.

Objective: was to determine the impact of preanesthesia consultation on anxiety scores.

Patients and methods: A single-center, observational study was carried out, with a descriptive, cross-sectional design and primary source. The anxiety score assessed using the APAIS scale (Amsterdam Preoperative Anxiety and Information Scale) was evaluated in adult participants before and after the pre-anesthetic consultation during the period December 2024 to April 2025. Statistical analysis was performed using the Wilcoxon, McNemar and chi-square tests. A P value < 0.05 was considered significant.

Results: A total of 190 participants were interviewed, of whom 180 were ultimately analyzed; 76.7% were women, and the mean age was 41.6 years. The most frequent procedures were general surgery and gynecological procedures. 86.7% had previously received anaesthesia. The prevalence of pre-consultation anxiety was 68.3%, decreasing to 47.2% after the consultation (p = 0.001). All interviewees between the ages of 18 and 25 reported anxiety before the pre-anaesthesia consultation (p = 0.031). The anesthetic technique that generated the greatest fear was general anaesthesia (42.8%), with the most frequently reported cause being fear of death (15.6%).

Conclusion: Preoperative anxiety is highly prevalent, and preanesthetic consultation could be an effective intervention to significantly reduce it.

背景:麻醉前咨询是降低择期手术患者焦虑评分的有效工具。焦虑可引起围手术期并发症。目的:探讨麻醉前咨询对患者焦虑评分的影响。患者和方法:采用描述性、横断面设计和主要来源的单中心观察性研究。在2024年12月至2025年4月期间,使用APAIS量表(阿姆斯特丹术前焦虑和信息量表)评估成人参与者在麻醉前会诊前后的焦虑评分。采用Wilcoxon、McNemar和卡方检验进行统计分析。A P值< 0.05被认为是显著的。结果:共采访了190名参与者,其中180人最终进行了分析;76.7%为女性,平均年龄41.6岁。最常见的手术是普通外科手术和妇科手术。86.7%曾接受过麻醉。会诊前焦虑患病率为68.3%,会诊后降至47.2% (p = 0.001)。所有年龄在18 - 25岁之间的受访者在麻醉前咨询前都报告了焦虑(p = 0.031)。引起最大恐惧的麻醉技术是全身麻醉(42.8%),最常见的报告原因是害怕死亡(15.6%)。结论:术前焦虑普遍存在,麻醉前会诊是有效的干预措施。
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引用次数: 0
Erector spinae plane block in neonates: Case study. 新生儿直立棘面阻滞:个案研究。
Pub Date : 2026-01-30 DOI: 10.1016/j.redare.2026.502019
J A Orozco Arango, P A Cruces Muñoz

Pain in neonates, if not adequately treated, can lead to long-term neurological and behavioural consequences. Among the most frequent causes are intrapartum fractures. Although rare, rib fractures represent a diagnostic and therapeutic challenge. This article presents the case of a 36-week neonate with a left rib fracture who exhibited symptoms such as inconsolable crying, feeding refusal, and oxygen desaturation. An ultrasound-guided erector spinae plane block (ESPB) was performed, resulting in significant clinical improvement without complications. Although ESPB has been widely used in adults and older children for the management of thoracic pain, its application in neonates is scarcely documented. This technique offers advantages over other regional analgesic methods, as it is associated with fewer adverse effects and provides direct analgesia to the thoracic nerves. Its use is suggested as a safe and effective alternative, particularly in non-surgical settings.

新生儿疼痛,如果治疗不当,可导致长期的神经和行为后果。其中最常见的原因是产时骨折。虽然罕见,但肋骨骨折对诊断和治疗都是一个挑战。本文报告一例36周大的新生儿左肋骨骨折,表现出哭闹、拒绝进食和氧饱和度过低等症状。超声引导直立脊柱平面阻滞(ESPB),临床效果明显改善,无并发症。虽然ESPB已广泛应用于成人和大龄儿童胸痛的治疗,但其在新生儿中的应用鲜有文献记载。与其他局部镇痛方法相比,该技术具有优势,因为它的不良反应较少,并可直接对胸神经进行镇痛。建议将其作为安全有效的替代方法使用,特别是在非手术环境中。
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引用次数: 0
Recuritment maneuvre: Facts and figures. 招聘策略:事实和数据。
Pub Date : 2026-01-28 DOI: 10.1016/j.redare.2026.501999
Z Salihoglu, E Salihoglu
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引用次数: 0
Practical guidance and recommendations for the safe management of the pediatric airway in anesthesia. 儿童气道麻醉安全管理的实用指南和建议。
Pub Date : 2026-01-28 DOI: 10.1016/j.redare.2026.501998
D Pérez-Ajami, F Escribá Alepuz, J D Jiménez Santana, B Aguado Rodríguez, E Estupiñán Valido

Advanced airway management in pediatric anesthesia has undergone substantial development with the incorporation of emerging technologies and strategies tailored to the unique anatomy and physiology of children. This review provides a critical appraisal of the clinical utility of tools such as videolaryngoscopy, high-flow nasal cannula oxygen therapy, and supraglottic devices, as well as specific techniques including the Bailey maneuver, fiberoptic-assisted intubation, and one-lung ventilation. Relevant studies published up to March 2025 were identified through searches in PubMed, Embase, Scopus, and Web of Science. Current evidence supports the use of these resources to enhance safety and effectiveness in complex scenarios, underscoring the importance of individualized device selection and specialized training. The integration of these strategies into tailored protocols represents a key step toward optimizing airway management in pediatric patients.

先进的气道管理在儿科麻醉经历了实质性的发展与新兴技术的结合和策略量身定制的独特的解剖和生理的儿童。本文综述了视频喉镜检查、高流量鼻插管氧疗和声门上设备等工具的临床应用,以及包括贝利操作、纤维辅助插管和单肺通气在内的特定技术。通过检索PubMed、Embase、Scopus和Web of Science,确定了截至2025年3月发表的相关研究。目前的证据支持使用这些资源来提高复杂情况下的安全性和有效性,强调个性化设备选择和专业培训的重要性。将这些策略整合到量身定制的方案中是优化儿科患者气道管理的关键一步。
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引用次数: 0
Subcutaneous emphysema as an airway emergency following tracheostomy closure. 气管切开术后的气道急症皮下肺气肿。
Pub Date : 2026-01-23 DOI: 10.1016/j.redare.2026.502018
M Linares, G Álvarez Roca, R Riera-Pérez, M López-Baamonde
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引用次数: 0
Comparative evaluation of the effect of application of external manoeuvres with no manoeuvre on glottis view during videolaryngoscopy in patients undergoing elective surgery with the head in neutral position. 头部择期手术中立位患者视颈喉镜检查时,外操与无操对声门视像影响的比较评价。
Pub Date : 2026-01-20 DOI: 10.1016/j.redare.2026.502016
S Panda, N Agrawal, K Jain V, A Gupta

Objectives: In patients with cervical spine injury, glottic visualization is difficult in the head-neutral position. The role of external laryngeal manoeuvres, such as backward-upward-rightward pressure (BURP) and jaw thrust in intubation outcomes remains unclear. We compared the effects of jaw thrust and BURP on the quality of glottic view with the head in a neutral position during C-MAC videolaryngoscopy.

Methods: In this self-controlled study, glottic view was assessed in 120 adult patients using a C-MAC videolaryngoscope with no manoeuvre, BURP, or jaw thrust. After induction, endotracheal intubation was performed according to Grupo allocation. Screenshots of the best glottic view were taken each time to assess the percentage of glottic opening (POGO) score, modified Cormack-Lehane (MCL) grade, and glottic opening area en píxeles cuadrados. Intubation times, ease of intubation, haemodynamics, and complications were also recorded.

Results: POGO scores (mean[DE]) were significantly higher with BURP (72.7[19.9]) and jaw thrust (60[26.3]) manoeuvres compared to no manoeuvre (25[26.9];P < 0.0001). Glottic opening area en píxeles cuadrados (P < 0.001) and MCL grades (P = 0.043) were considerably higher after the application of laryngeal manoeuvres. There were no significant differences in the duration of laryngoscopy and intubation times between Grupos; however, intubation was significantly easier with BURP (P = 0.021) and jaw thrust (P = 0.032).

Conclusion: External manoeuvres, such as BURP and jaw thrust, should improve glottic view during C-MAC videolaryngoscopy in patients with the head in a neutral position.

目的:在颈椎损伤患者中,头中位声门显像困难。喉外操作,如向后、向上、向右施压(BURP)和下颌推力在插管结果中的作用尚不清楚。我们比较了在C-MAC视频喉镜检查中,头部处于中立位时,下颌推力和BURP对声门图像质量的影响。方法:在这项自我控制的研究中,使用C-MAC视频喉镜评估120名成年患者的声门视图,无操作,BURP或颚推力。诱导后按分组进行气管插管。每次拍摄最佳声门视图的截图,以评估声门打开百分比(POGO)评分,修改Cormack-Lehane (MCL)评分和声门打开面积(píxeles cuadrados)。同时记录插管时间、插管难易程度、血流动力学及并发症。结果:与无运动(25[26.9])相比,BURP(72.7[19.9])和颌突(60[26.3])的POGO评分(mean[DE])显著高于BURP(72.7[19.9])和颌突(60[26.3])的POGO评分(mean[DE]);P结论:BURP和颌突等外部运动可改善头部处于中立位的C-MAC视频喉镜检查患者的声门视野。
{"title":"Comparative evaluation of the effect of application of external manoeuvres with no manoeuvre on glottis view during videolaryngoscopy in patients undergoing elective surgery with the head in neutral position.","authors":"S Panda, N Agrawal, K Jain V, A Gupta","doi":"10.1016/j.redare.2026.502016","DOIUrl":"10.1016/j.redare.2026.502016","url":null,"abstract":"<p><strong>Objectives: </strong>In patients with cervical spine injury, glottic visualization is difficult in the head-neutral position. The role of external laryngeal manoeuvres, such as backward-upward-rightward pressure (BURP) and jaw thrust in intubation outcomes remains unclear. We compared the effects of jaw thrust and BURP on the quality of glottic view with the head in a neutral position during C-MAC videolaryngoscopy.</p><p><strong>Methods: </strong>In this self-controlled study, glottic view was assessed in 120 adult patients using a C-MAC videolaryngoscope with no manoeuvre, BURP, or jaw thrust. After induction, endotracheal intubation was performed according to Grupo allocation. Screenshots of the best glottic view were taken each time to assess the percentage of glottic opening (POGO) score, modified Cormack-Lehane (MCL) grade, and glottic opening area en píxeles cuadrados. Intubation times, ease of intubation, haemodynamics, and complications were also recorded.</p><p><strong>Results: </strong>POGO scores (mean[DE]) were significantly higher with BURP (72.7[19.9]) and jaw thrust (60[26.3]) manoeuvres compared to no manoeuvre (25[26.9];P < 0.0001). Glottic opening area en píxeles cuadrados (P < 0.001) and MCL grades (P = 0.043) were considerably higher after the application of laryngeal manoeuvres. There were no significant differences in the duration of laryngoscopy and intubation times between Grupos; however, intubation was significantly easier with BURP (P = 0.021) and jaw thrust (P = 0.032).</p><p><strong>Conclusion: </strong>External manoeuvres, such as BURP and jaw thrust, should improve glottic view during C-MAC videolaryngoscopy in patients with the head in a neutral position.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502016"},"PeriodicalIF":0.0,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146032205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variability in the application of patient blood management programs in the Iberian peninsula. 伊比利亚半岛患者血液管理方案应用的可变性。
Pub Date : 2026-01-13 DOI: 10.1016/j.redare.2026.502017
J A García Erce, F Sabio, C Jericó, S Isabel Jorge, M Quintana Díaz, D Castro Paupério

Background: In 2010, the World Health Organization (WHO) called for global implementation of Patient Blood Management (PBM) programs to optimize transfusion practices and reduce variability in blood utilization. This study examines the evolution of red cell, platelet, and plasma consumption in Iberia (Spain and Portugal), comparing trends within the region and with European benchmarks like the United Kingdom, Germany, and Italy.

Methods: National transfusion activity reports from Spain, Portugal, the United Kingdom (2011-2023) were analyzed. Key metrics included transfusion rates per 1,000 inhabitants for red cells, platelets, and fresh frozen plasma. Statistical analyses were performed using Kruskal-Wallis tests and ANOVA to identify differences between countries and over time.

Results: From 2011 to 2023, red cell transfusion rates decreased by 30% in the UK, 6% in Spain, and 15% in Portugal. Germany showed a modest decline, while Italy maintained stable rates exceeding 40 units per 1,000 inhabitants. Platelet and plasma consumption exhibited distinct patterns, with Portugal showing a steeper decline compared to Spain, and the UK maintaining the lowest overall rates. Platelet consume is clearly increasing.

Conclusions: The analysis reveals significant differences in blood component utilization across Iberia and Europe, reflecting varying levels of PBM adoption. Despite WHO and Council of Europe recommendations, Iberian countries lag behind the UK in reducing red cell transfusion rates. These findings underscore the need for uniform PBM implementation to harmonize practices and optimize resource use, not only Red Cell Concentrates. The creation of the Iberian task-force (section of the Ibero-American PBM Society (SIAPBM) could be an opportunity to create the necessary awareness in our countries and become a meeting point between America and Europe.

背景:2010年,世界卫生组织(WHO)呼吁全球实施患者血液管理(PBM)计划,以优化输血实践并减少血液利用的可变性。本研究考察了伊比利亚半岛(西班牙和葡萄牙)红细胞、血小板和血浆消耗的演变,并将该地区的趋势与英国、德国和意大利等欧洲基准进行了比较。方法:分析西班牙、葡萄牙和英国2011-2023年国家输血活动报告。关键指标包括每1000名居民中红细胞、血小板和新鲜冷冻血浆的输血率。使用Kruskal-Wallis检验和方差分析进行统计分析,以确定国家之间和时间之间的差异。结果:从2011年到2023年,英国的红细胞输注率下降了30%,西班牙下降了6%,葡萄牙下降了15%。德国出现了小幅下降,而意大利保持了稳定的比率,超过每1000名居民40个单位。血小板和血浆消耗表现出不同的模式,与西班牙相比,葡萄牙的下降幅度更大,而英国保持最低的总体比率。血小板消耗明显增加。结论:分析揭示了伊比利亚和欧洲血液成分利用率的显著差异,反映了不同水平的PBM采用。尽管世卫组织和欧洲委员会提出了建议,但伊比利亚国家在降低红细胞输血率方面落后于英国。这些发现强调了统一PBM实施的必要性,以协调实践和优化资源利用,而不仅仅是红细胞浓缩物。伊比利亚特别工作组(伊比利亚-美洲PBM协会(SIAPBM)的一部分)的成立可能是一个在我们各国建立必要意识的机会,并成为美洲和欧洲之间的交汇点。
{"title":"Variability in the application of patient blood management programs in the Iberian peninsula.","authors":"J A García Erce, F Sabio, C Jericó, S Isabel Jorge, M Quintana Díaz, D Castro Paupério","doi":"10.1016/j.redare.2026.502017","DOIUrl":"10.1016/j.redare.2026.502017","url":null,"abstract":"<p><strong>Background: </strong>In 2010, the World Health Organization (WHO) called for global implementation of Patient Blood Management (PBM) programs to optimize transfusion practices and reduce variability in blood utilization. This study examines the evolution of red cell, platelet, and plasma consumption in Iberia (Spain and Portugal), comparing trends within the region and with European benchmarks like the United Kingdom, Germany, and Italy.</p><p><strong>Methods: </strong>National transfusion activity reports from Spain, Portugal, the United Kingdom (2011-2023) were analyzed. Key metrics included transfusion rates per 1,000 inhabitants for red cells, platelets, and fresh frozen plasma. Statistical analyses were performed using Kruskal-Wallis tests and ANOVA to identify differences between countries and over time.</p><p><strong>Results: </strong>From 2011 to 2023, red cell transfusion rates decreased by 30% in the UK, 6% in Spain, and 15% in Portugal. Germany showed a modest decline, while Italy maintained stable rates exceeding 40 units per 1,000 inhabitants. Platelet and plasma consumption exhibited distinct patterns, with Portugal showing a steeper decline compared to Spain, and the UK maintaining the lowest overall rates. Platelet consume is clearly increasing.</p><p><strong>Conclusions: </strong>The analysis reveals significant differences in blood component utilization across Iberia and Europe, reflecting varying levels of PBM adoption. Despite WHO and Council of Europe recommendations, Iberian countries lag behind the UK in reducing red cell transfusion rates. These findings underscore the need for uniform PBM implementation to harmonize practices and optimize resource use, not only Red Cell Concentrates. The creation of the Iberian task-force (section of the Ibero-American PBM Society (SIAPBM) could be an opportunity to create the necessary awareness in our countries and become a meeting point between America and Europe.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502017"},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Revista espanola de anestesiologia y reanimacion
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