Editorial Commentary: Osteochodral Autograft and Allograft Show Favorable Outcomes for High-Grade Hip Femoral Cartilage Lesions, but Caution Is Required for Impaction Injuries and Osteonecrosis

Edward C. Beck M.D., M.P.H. (Editorial Board), Nicholas A. Trasolini M.D. (Editorial Board)
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Abstract

Articular cartilage defects of the hip pose therapeutic challenges. Among patients undergoing hip arthroscopy for femoroacetabular impingement syndrome, more than 20% may have partial- or full-thickness chondral damage, and patients with high-grade (International Cartilage Repair Society grade 3 or 4) damage who undergo arthroscopic treatment of femoroacetabular impingement syndrome have higher rates of reoperation at 10-year follow-up. Arthroscopic and open techniques have been developed to translate cartilage restoration options initially developed in the knee for use in the hip. Arthroscopic options include chondroplasty, microfracture, biologic cartilage scaffolds, autologous chondrocyte implantation, and minced cartilage autograft (albeit more commonly in the acetabulum than the femoral head). Open techniques include autologous chondrocyte grafting, osteochondral autograft transfer (including mosaicplasty), osteochondral allograft transplantation, and arthroplasty. Open osteochondral allograft and autograft transplantation show improved patient-reported outcomes and forestall arthroplasty in young patients with high-grade cartilage defects of the femoral head. A recent review shows survivorship of 70% to 87.5% for allograft and 61.5% to 96% for autograft. At the same time, outcomes are not universally positive, particularly for patients with posttraumatic impaction injuries and high-grade osteonecrosis. Until further data better clarify the indications and contraindications, widespread adoption of open cartilage transplantation to the femoral head should be approached with caution, especially for older patients, in whom the gold standard of total hip arthroplasty has excellent survivorship at long-term follow-up.
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骨膜自体移植和同种异体移植对髋关节股骨关节软骨高级别病变的疗效良好,但需谨慎对待嵌顿损伤和骨坏死
髋关节关节软骨缺损对治疗提出了挑战。在接受髋关节镜治疗股髋臼撞击综合征的患者中,超过20%的患者可能存在部分或全层软骨损伤,并且在10年随访中,接受关节镜治疗股髋臼撞击综合征的高度(国际软骨修复学会分级3或4级)损伤患者的再手术率更高。关节镜和开放技术已经发展到将最初在膝关节开发的软骨修复方案用于髋关节。关节镜下的选择包括软骨成形术、微骨折、生物软骨支架、自体软骨细胞植入和自体碎软骨移植(尽管在髋臼比股骨头更常见)。开放技术包括自体软骨细胞移植、自体骨软骨移植(包括镶嵌成形术)、同种异体骨软骨移植和关节置换术。开放同种异体骨软骨移植和自体骨软骨移植在股骨头高度软骨缺损的年轻患者中显示出改善的患者报告的结果和预先的关节置换术。最近的一项综述显示同种异体移植的存活率为70%至87.5%,自体移植的存活率为61.5%至96%。同时,并不是所有的结果都是积极的,特别是对于创伤后嵌塞损伤和高度骨坏死的患者。在进一步的数据更好地阐明适应症和禁忌症之前,应谨慎对待广泛采用的股骨头开放软骨移植,特别是对于老年患者,在长期随访中,全髋关节置换术的金标准具有良好的生存率。
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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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