Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.08.039
David R Maldonado
Hip arthroscopy technique and innovation has revolutionized the surgical approach to femoroacetabular impingement syndrome (FAIS). Arthroscopic labral reconstruction is the gold-standard treatment for irreparable acetabular labral tears in FAIS surgery, and backed by robust long-term clinical data. However, cam-over-resection has become a prevalent complication, often co-occurring with irreparable labral tears in revision FAIS surgery. Revision, circumferential labral reconstruction, is a promising solution, particularly from a biomechanical perspective, in restoring the suction seal. Larger graft width is indicated in these cases.
{"title":"Editorial Commentary: In Cases of Cam Over-resection and Irreparable Hip Labral Tear Requiring Revision, Acetabular Circumferential Labral Reconstruction with Larger Graft Width Is Indicated.","authors":"David R Maldonado","doi":"10.1016/j.arthro.2024.08.039","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.039","url":null,"abstract":"<p><p>Hip arthroscopy technique and innovation has revolutionized the surgical approach to femoroacetabular impingement syndrome (FAIS). Arthroscopic labral reconstruction is the gold-standard treatment for irreparable acetabular labral tears in FAIS surgery, and backed by robust long-term clinical data. However, cam-over-resection has become a prevalent complication, often co-occurring with irreparable labral tears in revision FAIS surgery. Revision, circumferential labral reconstruction, is a promising solution, particularly from a biomechanical perspective, in restoring the suction seal. Larger graft width is indicated in these cases.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.08.011
Stephanie Choo, Julia A V Nuelle
Effective treatment of scaphoid pseudoarthrosis is critical to reduce the risk of progression to the potentially debilitating scaphoid nonunion advanced collapse including complications of persistent wrist joint instability, degenerative arthritis, decreased range of motion, chronic pain, and functional impairment. Both anatomic and fracture-related pathophysiology predispose patients to scaphoid nonunion, including limited retrograde blood flow, fracture location, and delay of appropriate treatment. Recent studies have demonstrated successful outcomes in treatment of scaphoid nonunions, with non-vascularized bone autograft, commonly from distal radius or iliac crest, as well as pedicled vascularized or free vascularized autograft with union rates varying from 84% to 100%. However, these surgical treatment options require large dissection, prompting a focused interest in minimally invasive arthroscopic options. Theoretically, minimally invasive technique mitigates against devitalizing scaphoid fracture fragments as well as damage to structures such as the joint capsule, ligaments, and already highly tenuous blood supply. Use of olecranon bone graft in combination with a minimally invasive arthroscopic technique and screw fixation is a reasonable option to minimize devitalizing the scaphoid fracture fragments and minimize damage to important soft-tissue structures.
{"title":"Olecranon Bone Autografting Combined with an Arthroscopic Approach for the Treatment Scaphoid Nonunion - An Important Technique for Wrist Surgeons.","authors":"Stephanie Choo, Julia A V Nuelle","doi":"10.1016/j.arthro.2024.08.011","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.011","url":null,"abstract":"<p><p>Effective treatment of scaphoid pseudoarthrosis is critical to reduce the risk of progression to the potentially debilitating scaphoid nonunion advanced collapse including complications of persistent wrist joint instability, degenerative arthritis, decreased range of motion, chronic pain, and functional impairment. Both anatomic and fracture-related pathophysiology predispose patients to scaphoid nonunion, including limited retrograde blood flow, fracture location, and delay of appropriate treatment. Recent studies have demonstrated successful outcomes in treatment of scaphoid nonunions, with non-vascularized bone autograft, commonly from distal radius or iliac crest, as well as pedicled vascularized or free vascularized autograft with union rates varying from 84% to 100%. However, these surgical treatment options require large dissection, prompting a focused interest in minimally invasive arthroscopic options. Theoretically, minimally invasive technique mitigates against devitalizing scaphoid fracture fragments as well as damage to structures such as the joint capsule, ligaments, and already highly tenuous blood supply. Use of olecranon bone graft in combination with a minimally invasive arthroscopic technique and screw fixation is a reasonable option to minimize devitalizing the scaphoid fracture fragments and minimize damage to important soft-tissue structures.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.09.002
James H Lubowitz, Nicholas P J Perry, Elizabeth Matzkin, Michael J Rossi
Arthroscopy Techniques is home to technical notes with video on all methods and procedures arthroscopic or related at https://www.arthroscopytechniques.org and https://www.youtube.com/@ArthroscopyTechniques. ATech publications run the gamut from classic to innovative, but where to start if one is a trainee, new in practice, or wishing to expand the breadth of one's practice? To fill this "gap," we introduce the Foundations of Arthroscopy Techniques Collection featuring technical notes with video detailing the essential fundamentals required to perform arthroscopy of the Shoulder, Elbow, Wrist, Hip, Knee, and Foot & Ankle.
{"title":"Introducing Foundations of Arthroscopy Techniques.","authors":"James H Lubowitz, Nicholas P J Perry, Elizabeth Matzkin, Michael J Rossi","doi":"10.1016/j.arthro.2024.09.002","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.09.002","url":null,"abstract":"<p><p>Arthroscopy Techniques is home to technical notes with video on all methods and procedures arthroscopic or related at https://www.arthroscopytechniques.org and https://www.youtube.com/@ArthroscopyTechniques. ATech publications run the gamut from classic to innovative, but where to start if one is a trainee, new in practice, or wishing to expand the breadth of one's practice? To fill this \"gap,\" we introduce the Foundations of Arthroscopy Techniques Collection featuring technical notes with video detailing the essential fundamentals required to perform arthroscopy of the Shoulder, Elbow, Wrist, Hip, Knee, and Foot & Ankle.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.08.042
Seth L Sherman, Robert M Putko
Medial opening-wedge high tibia osteotomy (MOWHTO) is a powerful tool in the surgical armamentarium to correct varus malalignment in patients with symptomatic medial compartment disease. This procedure has demonstrated proven results and long-term survivorship. Complications include cortical hinge fracture, symptomatic hardware, infection, delayed or non-union, and nerve injury. Varus recurrence is a known complication following MOWHTO. Risk factors are multifactorial, thought to include degree of alignment correction, extent of meniscus and cartilage pathology, and effectiveness of soft tissue balancing. Medial meniscus extrusion has been implicated in meniscus dysfunction and progression of degenerative joint disease. It is a recognized issue after meniscus preserving and transplant procedures that may have long-term sequela. This loss of hoop stress can lead to increased contact pressure, putting the diseased compartment at further risk. While it is certainly possible that extrusion matters for varus recurrence after MOWHTO, its role must be considered in the context of multiple other confounding factors.
{"title":"Editorial Commentary:Varus Recurrence After Medial Opening Wedge HTO.","authors":"Seth L Sherman, Robert M Putko","doi":"10.1016/j.arthro.2024.08.042","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.042","url":null,"abstract":"<p><p>Medial opening-wedge high tibia osteotomy (MOWHTO) is a powerful tool in the surgical armamentarium to correct varus malalignment in patients with symptomatic medial compartment disease. This procedure has demonstrated proven results and long-term survivorship. Complications include cortical hinge fracture, symptomatic hardware, infection, delayed or non-union, and nerve injury. Varus recurrence is a known complication following MOWHTO. Risk factors are multifactorial, thought to include degree of alignment correction, extent of meniscus and cartilage pathology, and effectiveness of soft tissue balancing. Medial meniscus extrusion has been implicated in meniscus dysfunction and progression of degenerative joint disease. It is a recognized issue after meniscus preserving and transplant procedures that may have long-term sequela. This loss of hoop stress can lead to increased contact pressure, putting the diseased compartment at further risk. While it is certainly possible that extrusion matters for varus recurrence after MOWHTO, its role must be considered in the context of multiple other confounding factors.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.09.004
Stephen C Weber
The Latarjet procedure, including coracoid transfer, is indicated for anterior glenohumeral instability and significant bone loss. However, even in experienced hands, the Latarjet procedure is associated with potential complications including neurovascular injury, graft resorption leading to painful or broken hardware and secondary subscapularis damage, prominent hardware, and graft non-union. An adjustable suture button technique may minimize hardware complications, and show low rates of non-union and resorption. (Perhaps, overly rigid fixation of the coracoid using screws contributes to the resorption.) Coracoid transfer may be avoided using various graft sources including iliac crest bone grafting. Despite loss of the "sling effect" provided by coracoid and conjoined tendon transfer, the procedure shows good outcomes with low recurrent instability for indicated patients. While technically complex, bone graft and suspensory fixation may be performed arthroscopically. Time will tell if this technique may supersede the Latarjet.
{"title":"Editorial Commentary: Arthroscopic Bone Grafting Using Suspensory Fixation for Anterior Glenohumeral Fixation with Bone Loss May Supersede Latarjet Using Coracoid Transfer.","authors":"Stephen C Weber","doi":"10.1016/j.arthro.2024.09.004","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.09.004","url":null,"abstract":"<p><p>The Latarjet procedure, including coracoid transfer, is indicated for anterior glenohumeral instability and significant bone loss. However, even in experienced hands, the Latarjet procedure is associated with potential complications including neurovascular injury, graft resorption leading to painful or broken hardware and secondary subscapularis damage, prominent hardware, and graft non-union. An adjustable suture button technique may minimize hardware complications, and show low rates of non-union and resorption. (Perhaps, overly rigid fixation of the coracoid using screws contributes to the resorption.) Coracoid transfer may be avoided using various graft sources including iliac crest bone grafting. Despite loss of the \"sling effect\" provided by coracoid and conjoined tendon transfer, the procedure shows good outcomes with low recurrent instability for indicated patients. While technically complex, bone graft and suspensory fixation may be performed arthroscopically. Time will tell if this technique may supersede the Latarjet.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.09.003
Christopher L McCrum
Adhesions are known to occur following arthroscopic, as well as open surgery of multiple joints, including after hip arthroscopy, resulting in pain, stiffness, and dysfunction. Adhesions of the labrum to the overlying hip capsule can lead to eversion of the labrum, and potentially compromise the suction seal, leading to microinstability and pain. Generally, patient reported outcomes improve after surgical lysis of adhesions, with or without concurrent correction of labral, chondral, or bony pathology. Arthroscopic placement of autograft or allograft spacers may be effective when adhesions between the labrum and capsule prevent an adequate suction seal. Prevention using biologics, such as angiotensin II receptor blockers (e.g., losartan), may inhibit TGF-β1 (transforming growth factor beta 1), which has been associated with fibrogenesis, tissue fibrosis, and scarring. Side effects of losartan are rare but include hypotension, dizziness, angioedema, and acute kidney injury when co-prescribed with NSAIDs, which are often used in heterotopic ossification prophylaxis in hip arthroscopy, and are a significant concern. More data on losartan use is required prior to broader adoption.
众所周知,关节镜手术和多关节开放手术(包括髋关节镜手术)后都会发生粘连,导致疼痛、僵硬和功能障碍。髋臼唇与上覆髋关节囊的粘连会导致髋臼唇外翻,并有可能破坏吸力密封,从而导致微不稳定和疼痛。一般来说,无论是否同时矫正唇囊、软骨或骨质病变,手术溶解粘连后患者的治疗效果都会有所改善。如果髋臼唇和髋臼囊之间的粘连阻碍了充分的吸入密封,关节镜下放置自体或异体移植物垫片可能会有效。使用血管紧张素 II 受体阻滞剂(如洛沙坦)等生物制剂进行预防,可抑制 TGF-β1(转化生长因子β1),而 TGF-β1与纤维化、组织纤维化和瘢痕形成有关。洛沙坦的副作用很少见,但包括低血压、头晕、血管性水肿,以及与非甾体抗炎药合用时的急性肾损伤。在更广泛地采用洛沙坦之前,需要更多关于洛沙坦使用情况的数据。
{"title":"Prevention and Treatment of Hip Adhesions Associated with Hip Arthroscopy Shows Positive Outcomes.","authors":"Christopher L McCrum","doi":"10.1016/j.arthro.2024.09.003","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.09.003","url":null,"abstract":"<p><p>Adhesions are known to occur following arthroscopic, as well as open surgery of multiple joints, including after hip arthroscopy, resulting in pain, stiffness, and dysfunction. Adhesions of the labrum to the overlying hip capsule can lead to eversion of the labrum, and potentially compromise the suction seal, leading to microinstability and pain. Generally, patient reported outcomes improve after surgical lysis of adhesions, with or without concurrent correction of labral, chondral, or bony pathology. Arthroscopic placement of autograft or allograft spacers may be effective when adhesions between the labrum and capsule prevent an adequate suction seal. Prevention using biologics, such as angiotensin II receptor blockers (e.g., losartan), may inhibit TGF-β1 (transforming growth factor beta 1), which has been associated with fibrogenesis, tissue fibrosis, and scarring. Side effects of losartan are rare but include hypotension, dizziness, angioedema, and acute kidney injury when co-prescribed with NSAIDs, which are often used in heterotopic ossification prophylaxis in hip arthroscopy, and are a significant concern. More data on losartan use is required prior to broader adoption.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-06DOI: 10.1016/j.arthro.2024.08.041
Jelle P van der List, David C Flanigan
Treatment of meniscus injuries have evolved from open to arthroscopic, from total to partial meniscectomy, and towards meniscus preservation. In theory, almost all tear types can be repaired, including root tears, (oblique) radial tears, horizontal cleavage tears, vertical tears, and even complex tears, as a result of improved surgical techniques and tools. Meniscus repair outcomes literature may be confounded by lack of inclusion of control groups, as well as concomitant anterior cruciate ligament injury and reconstruction, augmentation with fibrin clot or platelet-rich plasma or other biologics, suture configuration, and timing of repair. Radial tears represent a most difficult pattern due to limited fixation strength suturing circumferential fibers, and technical challenge. However, successful meniscus repair outcomes can be obtained in this difficult tear pattern. The key to success for any radial repair, regardless of technique, is to create a tensionless repair, and one of the key components is anatomic reduction of the meniscus. Using all inside suture devices to place a traction stitch can assist in reducing the meniscus. Then, AI or IO techniques may be used to repair the meniscus to the capsule in anatomic position (vertical mattress), with rip stop sutures to create horizontal or oblique sutures across the tear. With the meniscus reduced anatomically, mismatch from intra- to extra-capsular distance is prevented.
半月板损伤的治疗方法已从开放式发展到关节镜式,从半月板全切除术发展到半月板部分切除术,并逐渐发展到半月板保留术。理论上,由于手术技术和工具的改进,几乎所有类型的撕裂都可以修复,包括根部撕裂、(斜)径向撕裂、水平裂口撕裂、垂直撕裂,甚至复杂撕裂。半月板修复结果的文献可能因未纳入对照组、同时存在的前十字韧带损伤和重建、纤维蛋白凝块或富血小板血浆或其他生物制剂的增强、缝合结构和修复时机而受到混淆。径向撕裂是最困难的模式,因为缝合周缘纤维的固定强度有限,而且技术难度大。然而,在这种困难的撕裂模式下,半月板修复也能取得成功。无论采用哪种技术,半月板径向修复成功的关键在于实现无张力修复,而其中一个关键要素就是半月板的解剖缩小。使用所有内部缝合设备进行牵引缝合有助于缩小半月板。然后,可使用 AI 或 IO 技术将半月板修复到解剖位置的囊上(垂直床垫),并使用止裂缝合线在撕裂处进行水平或斜向缝合。随着半月板解剖位置的缩小,可避免囊内与囊外距离的不匹配。
{"title":"Editorial Commentary: Repair of Radial Meniscus Tears.","authors":"Jelle P van der List, David C Flanigan","doi":"10.1016/j.arthro.2024.08.041","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.041","url":null,"abstract":"<p><p>Treatment of meniscus injuries have evolved from open to arthroscopic, from total to partial meniscectomy, and towards meniscus preservation. In theory, almost all tear types can be repaired, including root tears, (oblique) radial tears, horizontal cleavage tears, vertical tears, and even complex tears, as a result of improved surgical techniques and tools. Meniscus repair outcomes literature may be confounded by lack of inclusion of control groups, as well as concomitant anterior cruciate ligament injury and reconstruction, augmentation with fibrin clot or platelet-rich plasma or other biologics, suture configuration, and timing of repair. Radial tears represent a most difficult pattern due to limited fixation strength suturing circumferential fibers, and technical challenge. However, successful meniscus repair outcomes can be obtained in this difficult tear pattern. The key to success for any radial repair, regardless of technique, is to create a tensionless repair, and one of the key components is anatomic reduction of the meniscus. Using all inside suture devices to place a traction stitch can assist in reducing the meniscus. Then, AI or IO techniques may be used to repair the meniscus to the capsule in anatomic position (vertical mattress), with rip stop sutures to create horizontal or oblique sutures across the tear. With the meniscus reduced anatomically, mismatch from intra- to extra-capsular distance is prevented.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.arthro.2024.08.027
Jesús Alfaro-Adrián
Medial meniscus extrusion (MME) is classically defined as radial displacement of ≥3 mm outside the tibial border. MME is usually seen in middle age patients and it is strongly associated with medial meniscus root (MMR) pathology and medial femorotibial compartment degenerative change. MMR tears are associated with cartilage defects of the medial femoral condyle (89%) and MME ≥3mm (67%). If MMR tears are associated with MME, high tibial osteotomy (HTO) combined with MMR repair may reduce MME and protect the medial compartment. Recent research shows combined MMR repair and HTO yield improved radiographic and functional outcomes.
{"title":"Medial Meniscal Root Repair Should Be Combined with High Tibial Osteotomy in Cases of Meniscal Extrusion.","authors":"Jesús Alfaro-Adrián","doi":"10.1016/j.arthro.2024.08.027","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.027","url":null,"abstract":"<p><p>Medial meniscus extrusion (MME) is classically defined as radial displacement of ≥3 mm outside the tibial border. MME is usually seen in middle age patients and it is strongly associated with medial meniscus root (MMR) pathology and medial femorotibial compartment degenerative change. MMR tears are associated with cartilage defects of the medial femoral condyle (89%) and MME ≥3mm (67%). If MMR tears are associated with MME, high tibial osteotomy (HTO) combined with MMR repair may reduce MME and protect the medial compartment. Recent research shows combined MMR repair and HTO yield improved radiographic and functional outcomes.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.arthro.2024.08.037
Dustin L Richter, Joshua L Harrison, Lauren Faber, Samuel Schrader, Yiliang Zhu, Carina Pierce, Leorrie Watson, Anil Shetty, Robert C Schenck
Purpose: To evaluate the effectiveness of microfragmented adipose tissue (MFAT) for pain relief and improved joint functionality in knee OA in a randomized, controlled clinical trial with 1-year follow-up.
Methods: Seventy-five patients were stratified by baseline pain level, and randomized to one of three treatment groups: MFAT, corticosteroid (CS), or saline control (C) injection. Patients 18 years of age or older, diagnosed with symptomatic knee osteoarthritis, with radiographic evidence of knee osteoarthritis and a visual analog pain scale (VAS) score of 3/10 or greater were included. Patients were excluded if they had any prior intra-articular knee injection, current knee ligamentous instability or an allergy to lidocaine/corticosteroid. The VAS pain scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the Knee Injury and Osteoarthritis Outcome score (KOOS) were recorded pre-procedure and at 2 weeks, 6 weeks, 3 and 6 months, and 1 year follow-up.
Results: MFAT demonstrated consistent and statistically significant improvements across all primary outcome measures for joint pain and functionality compared to C. For MFAT, there was a significant improvement over baseline at each follow-up, with median (95% CI) KOOS Pain score changes of 18.1 (11.1, 26.4) at week 2 to 27.8 (19.4, 37.5) at 1 year. For CS, the median KOOS pain score reached a maximum of 22.2 (15.3, 30.6) at week 2, only to level off to 13.9 (-2.8, 29.2), a level not statistically different from baseline, at 1 year. The median changes for C hovered around 6-11 points, with statistically significant improvements over baseline indicating a placebo effect. Similar trends were seen for the WOMAC Pain score and VAS Pain score.
Conclusions: In this study, MFAT demonstrated a clinically significant improvement in primary outcome scores compared with a saline control group, while the corticosteroid group only showed statistically significant improvement compared to the control group at 2 and 6 weeks. This finding indicates that MFAT may be a viable alternative treatment for patients with knee OA that fall into the orthopaedic treatment gap.
{"title":"Microfragmented adipose tissue injection reduced pain compared to a saline control among patients with symptomatic knee osteoarthritis during one-year follow-up: a randomized, controlled trial.","authors":"Dustin L Richter, Joshua L Harrison, Lauren Faber, Samuel Schrader, Yiliang Zhu, Carina Pierce, Leorrie Watson, Anil Shetty, Robert C Schenck","doi":"10.1016/j.arthro.2024.08.037","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.037","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness of microfragmented adipose tissue (MFAT) for pain relief and improved joint functionality in knee OA in a randomized, controlled clinical trial with 1-year follow-up.</p><p><strong>Methods: </strong>Seventy-five patients were stratified by baseline pain level, and randomized to one of three treatment groups: MFAT, corticosteroid (CS), or saline control (C) injection. Patients 18 years of age or older, diagnosed with symptomatic knee osteoarthritis, with radiographic evidence of knee osteoarthritis and a visual analog pain scale (VAS) score of 3/10 or greater were included. Patients were excluded if they had any prior intra-articular knee injection, current knee ligamentous instability or an allergy to lidocaine/corticosteroid. The VAS pain scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the Knee Injury and Osteoarthritis Outcome score (KOOS) were recorded pre-procedure and at 2 weeks, 6 weeks, 3 and 6 months, and 1 year follow-up.</p><p><strong>Results: </strong>MFAT demonstrated consistent and statistically significant improvements across all primary outcome measures for joint pain and functionality compared to C. For MFAT, there was a significant improvement over baseline at each follow-up, with median (95% CI) KOOS Pain score changes of 18.1 (11.1, 26.4) at week 2 to 27.8 (19.4, 37.5) at 1 year. For CS, the median KOOS pain score reached a maximum of 22.2 (15.3, 30.6) at week 2, only to level off to 13.9 (-2.8, 29.2), a level not statistically different from baseline, at 1 year. The median changes for C hovered around 6-11 points, with statistically significant improvements over baseline indicating a placebo effect. Similar trends were seen for the WOMAC Pain score and VAS Pain score.</p><p><strong>Conclusions: </strong>In this study, MFAT demonstrated a clinically significant improvement in primary outcome scores compared with a saline control group, while the corticosteroid group only showed statistically significant improvement compared to the control group at 2 and 6 weeks. This finding indicates that MFAT may be a viable alternative treatment for patients with knee OA that fall into the orthopaedic treatment gap.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.arthro.2024.08.035
John T Strony, Sunita Mengers, Lakshmanan Sivasundaram, Margaret Sinkler, Qian Wu, Chenya Zhao, Abdus Sattar, Michael J Salata, James E Voos, Michael R Karns
Background: The primary purpose was to compare ketorolac to oxycodone-acetaminophen with respect to pain and opioid consumption after arthroscopic meniscus surgery. The secondary purpose was to compare short-term functional outcomes between the two protocols.
Methods: A power analysis demonstrated that 43 patients were required. In this randomized control trial, patients with meniscal pathology undergoing arthroscopic meniscus surgery were included. Group 1 received oxycodone-acetaminophen alone. Group 2 received one dose of intravenous ketorolac intraoperatively, oral ketorolac upon discharge, and "rescue" oxycodone-acetaminophen. Patients recorded the number of opioid tablets consumed and visual analog pain scale (VAS) scores three times per day for five days postoperatively. Opioids were converted to morphine milligram equivalents (MME). VAS, Lysholm Knee Scoring Scale (LKSS), and Knee Injury and Osteoarthritis Outcome Score (KOOS) were obtained.
Results: Forty-eight patients were randomized. There were 25 patients in the control group and 23 patients in the ketorolac group. The mean age was 47.9 (±14.3) years. Fifty-two percent (n=25) of the population were female. Three patients (6.3%) underwent meniscal repair. During the first five days postoperatively, the mean VAS score (β= -13.2, SE=5.97, p=0.029) and the MME consumed were significantly lower (β=-4.7, SE=1.93, p=0.015) per time point in the ketorolac group relative to the control group. The control group had better LKSS (80.6 [SD 18.5] versus 65 [SD 21.5], p=0.016) and KOOS (74.1 [SD 16.7] versus 61.9 [SD 18.6], p=0.029) scores at 6 weeks. There were no significant differences in the rates of side effects.
Conclusions: An opioid-sparing pain protocol of intravenous and oral ketorolac is associated with significant reductions in VAS scores and MME consumption in the first five days after arthroscopic meniscus surgery. There were significant differences in patient-reported outcomes at final follow-up, favoring the control group. There were no significant differences in adverse reactions and side effects.
Level of evidence: Therapeutic Level II, prospective randomized-controlled trial.
{"title":"An Opioid-Sparing Pain Protocol of Intravenous and Oral Ketorolac Reduces Opioid Consumption and Pain Levels after Arthroscopic Meniscus Surgery: A Prospective, Randomized Controlled Trial.","authors":"John T Strony, Sunita Mengers, Lakshmanan Sivasundaram, Margaret Sinkler, Qian Wu, Chenya Zhao, Abdus Sattar, Michael J Salata, James E Voos, Michael R Karns","doi":"10.1016/j.arthro.2024.08.035","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.035","url":null,"abstract":"<p><strong>Background: </strong>The primary purpose was to compare ketorolac to oxycodone-acetaminophen with respect to pain and opioid consumption after arthroscopic meniscus surgery. The secondary purpose was to compare short-term functional outcomes between the two protocols.</p><p><strong>Methods: </strong>A power analysis demonstrated that 43 patients were required. In this randomized control trial, patients with meniscal pathology undergoing arthroscopic meniscus surgery were included. Group 1 received oxycodone-acetaminophen alone. Group 2 received one dose of intravenous ketorolac intraoperatively, oral ketorolac upon discharge, and \"rescue\" oxycodone-acetaminophen. Patients recorded the number of opioid tablets consumed and visual analog pain scale (VAS) scores three times per day for five days postoperatively. Opioids were converted to morphine milligram equivalents (MME). VAS, Lysholm Knee Scoring Scale (LKSS), and Knee Injury and Osteoarthritis Outcome Score (KOOS) were obtained.</p><p><strong>Results: </strong>Forty-eight patients were randomized. There were 25 patients in the control group and 23 patients in the ketorolac group. The mean age was 47.9 (±14.3) years. Fifty-two percent (n=25) of the population were female. Three patients (6.3%) underwent meniscal repair. During the first five days postoperatively, the mean VAS score (β= -13.2, SE=5.97, p=0.029) and the MME consumed were significantly lower (β=-4.7, SE=1.93, p=0.015) per time point in the ketorolac group relative to the control group. The control group had better LKSS (80.6 [SD 18.5] versus 65 [SD 21.5], p=0.016) and KOOS (74.1 [SD 16.7] versus 61.9 [SD 18.6], p=0.029) scores at 6 weeks. There were no significant differences in the rates of side effects.</p><p><strong>Conclusions: </strong>An opioid-sparing pain protocol of intravenous and oral ketorolac is associated with significant reductions in VAS scores and MME consumption in the first five days after arthroscopic meniscus surgery. There were significant differences in patient-reported outcomes at final follow-up, favoring the control group. There were no significant differences in adverse reactions and side effects.</p><p><strong>Level of evidence: </strong>Therapeutic Level II, prospective randomized-controlled trial.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}