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Editorial Commentary: In Cases of Cam Over-resection and Irreparable Hip Labral Tear Requiring Revision, Acetabular Circumferential Labral Reconstruction with Larger Graft Width Is Indicated. 编辑评论:在凸轮过度切除和不可修复的髋关节瓣膜撕裂需要翻修的病例中,髋臼环形瓣膜重建术应采用更大的移植物宽度。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.08.039
David R Maldonado

Hip arthroscopy technique and innovation has revolutionized the surgical approach to femoroacetabular impingement syndrome (FAIS). Arthroscopic labral reconstruction is the gold-standard treatment for irreparable acetabular labral tears in FAIS surgery, and backed by robust long-term clinical data. However, cam-over-resection has become a prevalent complication, often co-occurring with irreparable labral tears in revision FAIS surgery. Revision, circumferential labral reconstruction, is a promising solution, particularly from a biomechanical perspective, in restoring the suction seal. Larger graft width is indicated in these cases.

髋关节镜技术和创新彻底改变了股骨髋臼撞击综合征(FAIS)的手术方法。关节镜下髋臼唇重建术是治疗股骨髋臼撞击综合征手术中不可修复的髋臼唇撕裂的金标准疗法,并有可靠的长期临床数据支持。然而,凸轮过切已成为一种普遍的并发症,在 FAIS 翻修手术中经常与不可修复的唇裂同时出现。翻修、环形唇瓣重建是一种很有前景的解决方案,尤其是从生物力学角度来看,可以恢复吸力密封。在这些病例中,应采用较大的移植物宽度。
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引用次数: 0
Olecranon Bone Autografting Combined with an Arthroscopic Approach for the Treatment Scaphoid Nonunion - An Important Technique for Wrist Surgeons. 肩胛骨自体骨移植结合关节镜方法治疗肩胛骨骨不连--腕外科医生的一项重要技术。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.08.011
Stephanie Choo, Julia A V Nuelle

Effective treatment of scaphoid pseudoarthrosis is critical to reduce the risk of progression to the potentially debilitating scaphoid nonunion advanced collapse including complications of persistent wrist joint instability, degenerative arthritis, decreased range of motion, chronic pain, and functional impairment. Both anatomic and fracture-related pathophysiology predispose patients to scaphoid nonunion, including limited retrograde blood flow, fracture location, and delay of appropriate treatment. Recent studies have demonstrated successful outcomes in treatment of scaphoid nonunions, with non-vascularized bone autograft, commonly from distal radius or iliac crest, as well as pedicled vascularized or free vascularized autograft with union rates varying from 84% to 100%. However, these surgical treatment options require large dissection, prompting a focused interest in minimally invasive arthroscopic options. Theoretically, minimally invasive technique mitigates against devitalizing scaphoid fracture fragments as well as damage to structures such as the joint capsule, ligaments, and already highly tenuous blood supply. Use of olecranon bone graft in combination with a minimally invasive arthroscopic technique and screw fixation is a reasonable option to minimize devitalizing the scaphoid fracture fragments and minimize damage to important soft-tissue structures.

肩胛骨假关节的有效治疗对于降低发展为肩胛骨骨不连晚期塌陷的风险至关重要,包括持续性腕关节不稳定、退行性关节炎、活动范围减小、慢性疼痛和功能障碍等并发症。解剖学和骨折相关的病理生理学都使患者易患肩胛骨骨不连,包括逆行血流受限、骨折位置和适当治疗的延迟。最近的研究表明,使用无血管自体骨(通常取自桡骨远端或髂嵴)以及带蒂血管自体骨或游离血管自体骨治疗肩胛骨不愈合取得了成功,愈合率从84%到100%不等。然而,这些手术治疗方案都需要进行大面积剥离,这促使人们开始关注微创关节镜治疗方案。从理论上讲,微创技术可减轻肩胛骨骨折碎片脱落以及对关节囊、韧带等结构和已经非常脆弱的血液供应的损伤。将肩胛骨移植与微创关节镜技术和螺钉固定结合使用是一种合理的选择,可最大限度地减少肩胛骨骨折碎片的坏死,并最大限度地减少对重要软组织结构的损伤。
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引用次数: 0
Introducing Foundations of Arthroscopy Techniques. 关节镜技术基础介绍。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.09.002
James H Lubowitz, Nicholas P J Perry, Elizabeth Matzkin, Michael J Rossi

Arthroscopy Techniques is home to technical notes with video on all methods and procedures arthroscopic or related at https://www.arthroscopytechniques.org and https://www.youtube.com/@ArthroscopyTechniques. ATech publications run the gamut from classic to innovative, but where to start if one is a trainee, new in practice, or wishing to expand the breadth of one's practice? To fill this "gap," we introduce the Foundations of Arthroscopy Techniques Collection featuring technical notes with video detailing the essential fundamentals required to perform arthroscopy of the Shoulder, Elbow, Wrist, Hip, Knee, and Foot & Ankle.

关节镜技术》网站 https://www.arthroscopytechniques.org 和 https://www.youtube.com/@ArthroscopyTechniques 提供所有关节镜或相关方法和手术的技术说明和视频。从经典到创新,ATech 出版物包罗万象,但如果是实习生、新手或希望拓展业务范围的人,该从哪里入手呢?为了填补这一 "空白",我们推出了《关节镜技术基础》系列,其中的技术说明附有视频,详细介绍了肩关节镜、肘关节镜、腕关节镜、髋关节镜、膝关节镜以及足踝关节镜手术所需的基本要素。
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引用次数: 0
Editorial Commentary:Varus Recurrence After Medial Opening Wedge HTO. 编辑评论:内侧开口楔形 HTO 术后曲度复发。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.08.042
Seth L Sherman, Robert M Putko

Medial opening-wedge high tibia osteotomy (MOWHTO) is a powerful tool in the surgical armamentarium to correct varus malalignment in patients with symptomatic medial compartment disease. This procedure has demonstrated proven results and long-term survivorship. Complications include cortical hinge fracture, symptomatic hardware, infection, delayed or non-union, and nerve injury. Varus recurrence is a known complication following MOWHTO. Risk factors are multifactorial, thought to include degree of alignment correction, extent of meniscus and cartilage pathology, and effectiveness of soft tissue balancing. Medial meniscus extrusion has been implicated in meniscus dysfunction and progression of degenerative joint disease. It is a recognized issue after meniscus preserving and transplant procedures that may have long-term sequela. This loss of hoop stress can lead to increased contact pressure, putting the diseased compartment at further risk. While it is certainly possible that extrusion matters for varus recurrence after MOWHTO, its role must be considered in the context of multiple other confounding factors.

内侧开口楔形高位胫骨截骨术(MOWHTO)是一种强大的手术工具,可纠正有症状的内侧间室疾病患者的屈曲错位。该手术效果显著,可长期存活。并发症包括皮质铰链骨折、无症状硬件、感染、延迟或不愈合以及神经损伤。屈曲复发是MOWHTO术后的一种已知并发症。风险因素是多方面的,包括对位矫正程度、半月板和软骨病变程度以及软组织平衡的有效性。内侧半月板挤压与半月板功能障碍和退行性关节疾病的进展有关。这是半月板保留和移植手术后的一个公认问题,可能会造成长期后遗症。这种箍应力的丧失会导致接触压力增加,使病变区面临更大风险。当然,挤压可能会影响 MOWHTO 术后的屈曲复发,但其作用必须结合其他多种干扰因素加以考虑。
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引用次数: 0
Editorial Commentary: Arthroscopic Bone Grafting Using Suspensory Fixation for Anterior Glenohumeral Fixation with Bone Loss May Supersede Latarjet Using Coracoid Transfer. 编辑评论:关节镜下使用悬吊固定进行盂肱关节前部固定的骨移植可取代使用肩胛骨转移的Latarjet。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.09.004
Stephen C Weber

The Latarjet procedure, including coracoid transfer, is indicated for anterior glenohumeral instability and significant bone loss. However, even in experienced hands, the Latarjet procedure is associated with potential complications including neurovascular injury, graft resorption leading to painful or broken hardware and secondary subscapularis damage, prominent hardware, and graft non-union. An adjustable suture button technique may minimize hardware complications, and show low rates of non-union and resorption. (Perhaps, overly rigid fixation of the coracoid using screws contributes to the resorption.) Coracoid transfer may be avoided using various graft sources including iliac crest bone grafting. Despite loss of the "sling effect" provided by coracoid and conjoined tendon transfer, the procedure shows good outcomes with low recurrent instability for indicated patients. While technically complex, bone graft and suspensory fixation may be performed arthroscopically. Time will tell if this technique may supersede the Latarjet.

Latarjet手术(包括肩胛骨转移)适用于盂肱关节前部不稳定和骨质严重流失的情况。然而,即使是经验丰富的医生,Latarjet 手术也存在潜在的并发症,包括神经血管损伤、移植物吸收导致疼痛或硬件断裂以及继发性肩胛下肌损伤、硬件突出和移植物不愈合。可调节的缝合扣技术可最大限度地减少硬件并发症,并且显示出较低的不愈合和再吸收率。(使用螺钉对肩胛骨进行过于僵硬的固定可能会导致再吸收)。使用包括髂嵴植骨在内的各种移植来源可以避免冠状骨转移。尽管失去了肩胛骨和连体肌腱转移带来的 "吊索效应",但该手术效果良好,适用患者的复发不稳定性较低。虽然技术上比较复杂,但可以在关节镜下进行植骨和悬吊固定。这项技术能否取代 Latarjet,还需时间检验。
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引用次数: 0
Prevention and Treatment of Hip Adhesions Associated with Hip Arthroscopy Shows Positive Outcomes. 髋关节镜手术相关髋关节粘连的预防和治疗效果良好
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.09.003
Christopher L McCrum

Adhesions are known to occur following arthroscopic, as well as open surgery of multiple joints, including after hip arthroscopy, resulting in pain, stiffness, and dysfunction. Adhesions of the labrum to the overlying hip capsule can lead to eversion of the labrum, and potentially compromise the suction seal, leading to microinstability and pain. Generally, patient reported outcomes improve after surgical lysis of adhesions, with or without concurrent correction of labral, chondral, or bony pathology. Arthroscopic placement of autograft or allograft spacers may be effective when adhesions between the labrum and capsule prevent an adequate suction seal. Prevention using biologics, such as angiotensin II receptor blockers (e.g., losartan), may inhibit TGF-β1 (transforming growth factor beta 1), which has been associated with fibrogenesis, tissue fibrosis, and scarring. Side effects of losartan are rare but include hypotension, dizziness, angioedema, and acute kidney injury when co-prescribed with NSAIDs, which are often used in heterotopic ossification prophylaxis in hip arthroscopy, and are a significant concern. More data on losartan use is required prior to broader adoption.

众所周知,关节镜手术和多关节开放手术(包括髋关节镜手术)后都会发生粘连,导致疼痛、僵硬和功能障碍。髋臼唇与上覆髋关节囊的粘连会导致髋臼唇外翻,并有可能破坏吸力密封,从而导致微不稳定和疼痛。一般来说,无论是否同时矫正唇囊、软骨或骨质病变,手术溶解粘连后患者的治疗效果都会有所改善。如果髋臼唇和髋臼囊之间的粘连阻碍了充分的吸入密封,关节镜下放置自体或异体移植物垫片可能会有效。使用血管紧张素 II 受体阻滞剂(如洛沙坦)等生物制剂进行预防,可抑制 TGF-β1(转化生长因子β1),而 TGF-β1与纤维化、组织纤维化和瘢痕形成有关。洛沙坦的副作用很少见,但包括低血压、头晕、血管性水肿,以及与非甾体抗炎药合用时的急性肾损伤。在更广泛地采用洛沙坦之前,需要更多关于洛沙坦使用情况的数据。
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引用次数: 0
Editorial Commentary: Repair of Radial Meniscus Tears. 编辑评论:修复径向半月板撕裂。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-06 DOI: 10.1016/j.arthro.2024.08.041
Jelle P van der List, David C Flanigan

Treatment of meniscus injuries have evolved from open to arthroscopic, from total to partial meniscectomy, and towards meniscus preservation. In theory, almost all tear types can be repaired, including root tears, (oblique) radial tears, horizontal cleavage tears, vertical tears, and even complex tears, as a result of improved surgical techniques and tools. Meniscus repair outcomes literature may be confounded by lack of inclusion of control groups, as well as concomitant anterior cruciate ligament injury and reconstruction, augmentation with fibrin clot or platelet-rich plasma or other biologics, suture configuration, and timing of repair. Radial tears represent a most difficult pattern due to limited fixation strength suturing circumferential fibers, and technical challenge. However, successful meniscus repair outcomes can be obtained in this difficult tear pattern. The key to success for any radial repair, regardless of technique, is to create a tensionless repair, and one of the key components is anatomic reduction of the meniscus. Using all inside suture devices to place a traction stitch can assist in reducing the meniscus. Then, AI or IO techniques may be used to repair the meniscus to the capsule in anatomic position (vertical mattress), with rip stop sutures to create horizontal or oblique sutures across the tear. With the meniscus reduced anatomically, mismatch from intra- to extra-capsular distance is prevented.

半月板损伤的治疗方法已从开放式发展到关节镜式,从半月板全切除术发展到半月板部分切除术,并逐渐发展到半月板保留术。理论上,由于手术技术和工具的改进,几乎所有类型的撕裂都可以修复,包括根部撕裂、(斜)径向撕裂、水平裂口撕裂、垂直撕裂,甚至复杂撕裂。半月板修复结果的文献可能因未纳入对照组、同时存在的前十字韧带损伤和重建、纤维蛋白凝块或富血小板血浆或其他生物制剂的增强、缝合结构和修复时机而受到混淆。径向撕裂是最困难的模式,因为缝合周缘纤维的固定强度有限,而且技术难度大。然而,在这种困难的撕裂模式下,半月板修复也能取得成功。无论采用哪种技术,半月板径向修复成功的关键在于实现无张力修复,而其中一个关键要素就是半月板的解剖缩小。使用所有内部缝合设备进行牵引缝合有助于缩小半月板。然后,可使用 AI 或 IO 技术将半月板修复到解剖位置的囊上(垂直床垫),并使用止裂缝合线在撕裂处进行水平或斜向缝合。随着半月板解剖位置的缩小,可避免囊内与囊外距离的不匹配。
{"title":"Editorial Commentary: Repair of Radial Meniscus Tears.","authors":"Jelle P van der List, David C Flanigan","doi":"10.1016/j.arthro.2024.08.041","DOIUrl":"https://doi.org/10.1016/j.arthro.2024.08.041","url":null,"abstract":"<p><p>Treatment of meniscus injuries have evolved from open to arthroscopic, from total to partial meniscectomy, and towards meniscus preservation. In theory, almost all tear types can be repaired, including root tears, (oblique) radial tears, horizontal cleavage tears, vertical tears, and even complex tears, as a result of improved surgical techniques and tools. Meniscus repair outcomes literature may be confounded by lack of inclusion of control groups, as well as concomitant anterior cruciate ligament injury and reconstruction, augmentation with fibrin clot or platelet-rich plasma or other biologics, suture configuration, and timing of repair. Radial tears represent a most difficult pattern due to limited fixation strength suturing circumferential fibers, and technical challenge. However, successful meniscus repair outcomes can be obtained in this difficult tear pattern. The key to success for any radial repair, regardless of technique, is to create a tensionless repair, and one of the key components is anatomic reduction of the meniscus. Using all inside suture devices to place a traction stitch can assist in reducing the meniscus. Then, AI or IO techniques may be used to repair the meniscus to the capsule in anatomic position (vertical mattress), with rip stop sutures to create horizontal or oblique sutures across the tear. With the meniscus reduced anatomically, mismatch from intra- to extra-capsular distance is prevented.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medial Meniscal Root Repair Should Be Combined with High Tibial Osteotomy in Cases of Meniscal Extrusion. 在半月板外翻的病例中,内侧半月板根部修复应与胫骨高位截骨术相结合。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-05 DOI: 10.1016/j.arthro.2024.08.027
Jesús Alfaro-Adrián

Medial meniscus extrusion (MME) is classically defined as radial displacement of ≥3 mm outside the tibial border. MME is usually seen in middle age patients and it is strongly associated with medial meniscus root (MMR) pathology and medial femorotibial compartment degenerative change. MMR tears are associated with cartilage defects of the medial femoral condyle (89%) and MME ≥3mm (67%). If MMR tears are associated with MME, high tibial osteotomy (HTO) combined with MMR repair may reduce MME and protect the medial compartment. Recent research shows combined MMR repair and HTO yield improved radiographic and functional outcomes.

内侧半月板挤出(MME)的经典定义是胫骨边界外≥3 毫米的径向位移。MME通常见于中年患者,与内侧半月板根(MMR)病变和股胫骨内侧室退行性改变密切相关。MMR撕裂与股骨内侧髁软骨缺损(89%)和MME≥3毫米(67%)有关。如果股内侧软骨撕裂与股内侧髁软骨缺损有关,则高位胫骨截骨术(HTO)与股内侧软骨撕裂修复术相结合可减少股内侧髁软骨缺损,保护股内侧髁。最近的研究表明,结合MMR修复术和高位胫骨截骨术可改善影像学和功能效果。
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引用次数: 0
Microfragmented adipose tissue injection reduced pain compared to a saline control among patients with symptomatic knee osteoarthritis during one-year follow-up: a randomized, controlled trial. 与生理盐水对照组相比,微碎屑脂肪组织注射液可在一年的随访期间减轻无症状膝骨关节炎患者的疼痛:一项随机对照试验。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-05 DOI: 10.1016/j.arthro.2024.08.037
Dustin L Richter, Joshua L Harrison, Lauren Faber, Samuel Schrader, Yiliang Zhu, Carina Pierce, Leorrie Watson, Anil Shetty, Robert C Schenck

Purpose: To evaluate the effectiveness of microfragmented adipose tissue (MFAT) for pain relief and improved joint functionality in knee OA in a randomized, controlled clinical trial with 1-year follow-up.

Methods: Seventy-five patients were stratified by baseline pain level, and randomized to one of three treatment groups: MFAT, corticosteroid (CS), or saline control (C) injection. Patients 18 years of age or older, diagnosed with symptomatic knee osteoarthritis, with radiographic evidence of knee osteoarthritis and a visual analog pain scale (VAS) score of 3/10 or greater were included. Patients were excluded if they had any prior intra-articular knee injection, current knee ligamentous instability or an allergy to lidocaine/corticosteroid. The VAS pain scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the Knee Injury and Osteoarthritis Outcome score (KOOS) were recorded pre-procedure and at 2 weeks, 6 weeks, 3 and 6 months, and 1 year follow-up.

Results: MFAT demonstrated consistent and statistically significant improvements across all primary outcome measures for joint pain and functionality compared to C. For MFAT, there was a significant improvement over baseline at each follow-up, with median (95% CI) KOOS Pain score changes of 18.1 (11.1, 26.4) at week 2 to 27.8 (19.4, 37.5) at 1 year. For CS, the median KOOS pain score reached a maximum of 22.2 (15.3, 30.6) at week 2, only to level off to 13.9 (-2.8, 29.2), a level not statistically different from baseline, at 1 year. The median changes for C hovered around 6-11 points, with statistically significant improvements over baseline indicating a placebo effect. Similar trends were seen for the WOMAC Pain score and VAS Pain score.

Conclusions: In this study, MFAT demonstrated a clinically significant improvement in primary outcome scores compared with a saline control group, while the corticosteroid group only showed statistically significant improvement compared to the control group at 2 and 6 weeks. This finding indicates that MFAT may be a viable alternative treatment for patients with knee OA that fall into the orthopaedic treatment gap.

目的:在一项为期 1 年的随机对照临床试验中,评估微碎屑脂肪组织(MFAT)在缓解膝关节 OA 疼痛和改善关节功能方面的效果:根据基线疼痛程度对 75 名患者进行分层,并随机分为三个治疗组:注射 MFAT、皮质类固醇 (CS) 或生理盐水对照 (C)。患者年龄在 18 岁或以上,确诊为无症状膝关节骨性关节炎,膝关节骨性关节炎有放射学证据,视觉模拟疼痛量表(VAS)评分在 3/10 或以上。曾进行过膝关节内注射、目前膝关节韧带不稳定或对利多卡因/皮质类固醇过敏的患者除外。术前、2周、6周、3个月和6个月以及1年的随访中记录了VAS疼痛量表、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)以及膝关节损伤和骨关节炎结果评分(KOOS):MFAT与C相比,在关节疼痛和功能方面的所有主要结果指标上都有一致且具有统计学意义的改善。对于MFAT,每次随访都比基线有显著改善,KOOS疼痛评分的中位数(95% CI)变化从第2周的18.1(11.1,26.4)到1年时的27.8(19.4,37.5)。对于 CS,KOOS 疼痛评分的中位数在第 2 周达到最高值 22.2(15.3,30.6),但在 1 年后降至 13.9(-2.8,29.2),与基线无统计学差异。C 的中位变化徘徊在 6-11 点之间,与基线相比有统计学意义的显著改善表明存在安慰剂效应。WOMAC疼痛评分和VAS疼痛评分也有类似趋势:在这项研究中,与生理盐水对照组相比,MFAT 在主要结果评分方面有显著的临床改善,而与对照组相比,皮质类固醇组仅在 2 周和 6 周时有统计学意义上的显著改善。这一结果表明,MFAT 可能是骨科治疗空白领域膝关节 OA 患者的一种可行的替代治疗方法。
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引用次数: 0
An Opioid-Sparing Pain Protocol of Intravenous and Oral Ketorolac Reduces Opioid Consumption and Pain Levels after Arthroscopic Meniscus Surgery: A Prospective, Randomized Controlled Trial. 静脉注射和口服酮咯酸的阿片类稀释止痛方案可减少关节镜半月板手术后阿片类药物的用量和疼痛程度:一项前瞻性随机对照试验。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-05 DOI: 10.1016/j.arthro.2024.08.035
John T Strony, Sunita Mengers, Lakshmanan Sivasundaram, Margaret Sinkler, Qian Wu, Chenya Zhao, Abdus Sattar, Michael J Salata, James E Voos, Michael R Karns

Background: The primary purpose was to compare ketorolac to oxycodone-acetaminophen with respect to pain and opioid consumption after arthroscopic meniscus surgery. The secondary purpose was to compare short-term functional outcomes between the two protocols.

Methods: A power analysis demonstrated that 43 patients were required. In this randomized control trial, patients with meniscal pathology undergoing arthroscopic meniscus surgery were included. Group 1 received oxycodone-acetaminophen alone. Group 2 received one dose of intravenous ketorolac intraoperatively, oral ketorolac upon discharge, and "rescue" oxycodone-acetaminophen. Patients recorded the number of opioid tablets consumed and visual analog pain scale (VAS) scores three times per day for five days postoperatively. Opioids were converted to morphine milligram equivalents (MME). VAS, Lysholm Knee Scoring Scale (LKSS), and Knee Injury and Osteoarthritis Outcome Score (KOOS) were obtained.

Results: Forty-eight patients were randomized. There were 25 patients in the control group and 23 patients in the ketorolac group. The mean age was 47.9 (±14.3) years. Fifty-two percent (n=25) of the population were female. Three patients (6.3%) underwent meniscal repair. During the first five days postoperatively, the mean VAS score (β= -13.2, SE=5.97, p=0.029) and the MME consumed were significantly lower (β=-4.7, SE=1.93, p=0.015) per time point in the ketorolac group relative to the control group. The control group had better LKSS (80.6 [SD 18.5] versus 65 [SD 21.5], p=0.016) and KOOS (74.1 [SD 16.7] versus 61.9 [SD 18.6], p=0.029) scores at 6 weeks. There were no significant differences in the rates of side effects.

Conclusions: An opioid-sparing pain protocol of intravenous and oral ketorolac is associated with significant reductions in VAS scores and MME consumption in the first five days after arthroscopic meniscus surgery. There were significant differences in patient-reported outcomes at final follow-up, favoring the control group. There were no significant differences in adverse reactions and side effects.

Level of evidence: Therapeutic Level II, prospective randomized-controlled trial.

研究背景主要目的是比较酮咯酸和羟考酮-对乙酰氨基酚在关节镜半月板手术后的疼痛和阿片类药物消耗量。次要目的是比较两种方案的短期功能效果:方法:功率分析表明需要 43 名患者。在这项随机对照试验中,纳入了接受关节镜半月板手术的半月板病变患者。第一组只接受羟考酮-对乙酰氨基酚治疗。第二组患者术中静脉注射一剂酮咯酸,出院时口服酮咯酸,并接受羟考酮-乙酰氨基酚 "救治"。术后五天内,患者每天三次记录阿片类药物的用量和视觉模拟疼痛量表(VAS)评分。阿片类药物被转换为吗啡毫克当量(MME)。结果:48 名患者接受了随机治疗。结果:48 名患者接受了随机治疗,其中对照组 25 人,酮咯酸组 23 人。平均年龄为 47.9 (±14.3) 岁。52%(n=25)的患者为女性。三名患者(6.3%)接受了半月板修复术。术后前五天,酮咯酸组的平均VAS评分(β= -13.2,SE=5.97,P=0.029)和MME消耗量(β=-4.7,SE=1.93,P=0.015)均显著低于对照组。对照组在 6 周时的 LKSS(80.6 [SD 18.5] 对 65 [SD 21.5],p=0.016)和 KOOS(74.1 [SD 16.7] 对 61.9 [SD 18.6],p=0.029)评分更好。副作用发生率无明显差异:结论:静脉注射和口服酮咯酸的阿片类镇痛方案可显著降低关节镜半月板手术后头五天的VAS评分和MME用量。在最终随访中,患者报告的结果存在明显差异,对照组更优。不良反应和副作用无明显差异:证据级别:二级治疗,前瞻性随机对照试验。
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引用次数: 0
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Arthroscopy-The Journal of Arthroscopic and Related Surgery
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