Advancement of organ-on-chip towards next generation medical technology

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology Biosensors and Bioelectronics: X Pub Date : 2024-04-25 DOI:10.1016/j.biosx.2024.100480

Garima Singh , Annu Mishra , Ashish Mathur , Sakshi Shastri , Anam Nizam , Amber Rizwan , Agampreet Singh Dadial , Anam Firdous , Homa Hassan

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Abstract

Organ-on-a-Chip, or OOC, is a widely discussed topic in science due to its many unique advantages in the biomedical field. Nevertheless, there is still much to learn about OOC's various aspects of conception and its significance for the advancement of medical technology in the future. A platform for organs-on-a-chip must go through the fabrication process. Various manufacturing processes were also used depending on the required disease modelling and drug screening. Organs on a chip technology included the Brain-On-Chip, Kidney-On-Chip, Liver-On-Chip, and Heart-On-Chip. In order to provide new beginnings with a thorough understanding of OOC, we have studied the most recent developments in organ-on-a-chip expertise and critically assessed its relevant features in this research.

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推动器官芯片向下一代医疗技术发展

芯片上器官（Organ-on-a-Chip，简称 OOC）因其在生物医学领域的诸多独特优势而成为科学界广泛讨论的话题。然而，关于 OOC 的各方面概念及其对未来医疗技术进步的意义，还有很多东西需要了解。芯片上的器官平台必须经过制造过程。根据所需的疾病建模和药物筛选，还采用了不同的制造工艺。芯片器官技术包括脑芯片、肾芯片、肝芯片和心芯片。为了在新的起点上全面了解芯片上器官技术，我们研究了芯片上器官技术的最新发展，并在本研究中对其相关特性进行了批判性评估。

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来源期刊

Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

4.60

自引率

0.00%

发文量

166

审稿时长

54 days

期刊介绍： Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.