{"title":"GREEN ANTI-BIOFILM AGENTS: A MINI-REVIEW","authors":"Shireen Adeeb Mujtaba Ali","doi":"10.36106/ijar/6802147","DOIUrl":null,"url":null,"abstract":"Microbial biolm is the polymeric matrix formed by coordinated assembly of species of similar or different\nmicroorganisms. The bacteria in form of biolms are more resistant to drugs than compared to their planktonic\ncounterparts, hence making it difcult to deal with biolm-associated nosocomial and medical device infections. Around $11 billion is annual\nexpenditure reported to be employed in healthcare to deal with biolm infections but the success rates are very low. Studies on natural anti-biolm\nagents from the last two decades notably demonstrated their biolm modulation properties. Therefore, present state of affairs demands active\npursual for non-toxic natural anti-biolm agents. In this mini-review article, we summarize green anti-biolm agents: antimicrobial peptides\n(AMPs), phytochemicals, biosurfactants, nanoparticles, and weak organic acids (WOA) with a brief note on their mode of action.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian journal of applied research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/ijar/6802147","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Microbial biolm is the polymeric matrix formed by coordinated assembly of species of similar or different
microorganisms. The bacteria in form of biolms are more resistant to drugs than compared to their planktonic
counterparts, hence making it difcult to deal with biolm-associated nosocomial and medical device infections. Around $11 billion is annual
expenditure reported to be employed in healthcare to deal with biolm infections but the success rates are very low. Studies on natural anti-biolm
agents from the last two decades notably demonstrated their biolm modulation properties. Therefore, present state of affairs demands active
pursual for non-toxic natural anti-biolm agents. In this mini-review article, we summarize green anti-biolm agents: antimicrobial peptides
(AMPs), phytochemicals, biosurfactants, nanoparticles, and weak organic acids (WOA) with a brief note on their mode of action.
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