Comparative antioxidant activity of Sesame root and leaf extract - An In-vitro study

Abstract

Universe has millions and millions of plants, but not all the plants have medicinal values.  One such gift from nature is Sesame and is crowned as the “Queen of oilseed crops” due to its various medical properties like anti-inflammatory, antioxidant, anti- microbial etc. This research paper aims to compare the antioxidant activity of sesame leaf extract and sesame root extract with the standard ascorbic acid using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide (H2O2) assay. Different concentrations of the extracts and ascorbic acid were prepared (10 µg/mL, 20 µg/mL, 30 µg/mL, 40 µg/mL, and 50 µg/mL), and the antioxidant activity was measured. The results indicate that both sesame leaf extract and sesame root extract exhibit antioxidant activity, with sesame leaf extract showing slightly higher activity than sesame root extract. The findings suggest that sesame leaf extract has potential as a natural antioxidant source and could be used as an alternative to synthetic antioxidants. Overall, this study provides valuable information on the potential health benefits of sesame extracts and highlights the importance of natural antioxidants in preventing free radical damage and associated diseases.