Queratopatía cristalina secundaria al uso de ciprofloxacino tras cirugía de catarata con comprobación por estudio histopatológico: Reporte de un caso y revisión de la literatura

Q3 Medicine Archivos De La Sociedad Espanola De Oftalmologia Pub Date : 2024-06-01 DOI:10.1016/j.oftal.2024.03.007

P.A. García-Uribe, M. Preciado

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Abstract

Objective

To report the case of a 75-year-old patient who presented crystalline keratopathy secondary to the use of topical ciprofloxacin with histopathological verification, after cataract surgery without complications.

Method

Case report with clinical and photographic follow-up, as well as slides with samples of epithelium and crystalline deposits.

Results

Corneal deposits resolved after drug suspension, topical lubricant change, and subsequent surgical debridement. The histopathological examination reported epithelial cells and basophilic particles compatible with drug precipitates.

Conclusions

Crystalline keratopathy is a condition in which crystals of various kinds are deposited in the corneal epithelium and/or in the anterior stroma. It may have an infectious, pharmacological cause or, in rarer cases, corneal dystrophies. Certain factors such as a previous epithelial defect, systemic pathology with diabetes mellitus, ocular surgery and previous dry eye can favor the deposition of ciprofloxacin leading to the formation of a keratopathy.

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白内障手术后继发于环丙沙星的结晶性角膜病变及组织病理学验证：病例报告和文献综述。

方法病例报告，包括临床和照片随访，以及上皮和晶体沉积物样本的切片。结果停药、更换局部润滑剂和随后的手术清创后，角膜沉积物消退。结论结晶性角膜病是指角膜上皮和/或前基质中沉积了各种晶体。结晶性角膜病的病因可能是感染、药物，也可能是角膜营养不良，但较为罕见。某些因素，如先前的上皮缺损、糖尿病引起的全身性病变、眼部手术和先前的干眼症，都可能有利于环丙沙星的沉积，从而导致角膜病变的形成。

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来源期刊

Archivos De La Sociedad Espanola De Oftalmologia Medicine-Ophthalmology

CiteScore

1.20

自引率

0.00%

发文量

109

审稿时长

78 days

期刊介绍： La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.