Synthetic reprogramming of plant developmental and biochemical pathways

IF 7.1 2区 工程技术 Q1 BIOCHEMICAL RESEARCH METHODS Current opinion in biotechnology Pub Date : 2024-04-30 DOI:10.1016/j.copbio.2024.103139
Shammi Akter , Oscar Castaneda-Méndez , Jesús Beltrán
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Abstract

Plant synthetic biology (Plant SynBio) is an emerging field with the potential to enhance agriculture, human health, and sustainability. Integrating genetic tools and engineering principles, Plant SynBio aims to manipulate cellular functions and construct novel biochemical pathways to develop plants with new phenotypic traits, enhanced yield, and be able to produce natural products and pharmaceuticals. This review compiles research efforts in reprogramming plant developmental and biochemical pathways. We highlight studies leveraging new gene expression toolkits to alter plant architecture for improved performance in model and crop systems and to produce useful metabolites in plant tissues. Furthermore, we provide insights into the challenges and opportunities associated with the adoption of Plant SynBio in addressing complex issues impacting agriculture and human health.

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植物发育和生化途径的合成重编程
植物合成生物学(Plant SynBio)是一个新兴领域,具有促进农业、人类健康和可持续发展的潜力。植物合成生物学整合了遗传工具和工程原理,旨在操纵细胞功能和构建新型生化途径,从而培育出具有新表型性状的植物,提高产量,并能够生产天然产品和药品。本综述汇编了重编程植物发育和生化途径方面的研究工作。我们重点介绍了利用新的基因表达工具包改变植物结构以提高其在模型和作物系统中的表现以及在植物组织中生产有用代谢物的研究。此外,我们还深入探讨了采用植物合成生物技术解决影响农业和人类健康的复杂问题所面临的挑战和机遇。
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来源期刊
Current opinion in biotechnology
Current opinion in biotechnology 工程技术-生化研究方法
CiteScore
16.20
自引率
2.60%
发文量
226
审稿时长
4-8 weeks
期刊介绍: Current Opinion in Biotechnology (COBIOT) is renowned for publishing authoritative, comprehensive, and systematic reviews. By offering clear and readable syntheses of current advances in biotechnology, COBIOT assists specialists in staying updated on the latest developments in the field. Expert authors annotate the most noteworthy papers from the vast array of information available today, providing readers with valuable insights and saving them time. As part of the Current Opinion and Research (CO+RE) suite of journals, COBIOT is accompanied by the open-access primary research journal, Current Research in Biotechnology (CRBIOT). Leveraging the editorial excellence, high impact, and global reach of the Current Opinion legacy, CO+RE journals ensure they are widely read resources integral to scientists' workflows. COBIOT is organized into themed sections, each reviewed once a year. These themes cover various areas of biotechnology, including analytical biotechnology, plant biotechnology, food biotechnology, energy biotechnology, environmental biotechnology, systems biology, nanobiotechnology, tissue, cell, and pathway engineering, chemical biotechnology, and pharmaceutical biotechnology.
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