Lack of racial and ethnic disparities in mortality in minority patients hospitalised with COVID-19 in a mid-Atlantic healthcare system

IF 3.6 3区 医学 Q1 RESPIRATORY SYSTEM BMJ Open Respiratory Research Pub Date : 2024-05-01 DOI:10.1136/bmjresp-2024-002310
Panagis Galiatsatos, Brian Garibaldi, Dapeng Yao, Yanxun Xu, Jamie Perin, Andi Shahu, John W Jackson, Damani Piggott, Oluwaseun Falade-Nwulia, Jocelyn Shubella, Henry Michtalik, Harolyn M E Belcher, Nadia N Hansel, Sherita Golden
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Abstract

Introduction In the USA, minoritised communities (racial and ethnic) have suffered disproportionately from COVID-19 compared with non-Hispanic white communities. In a large cohort of patients hospitalised for COVID-19 in a healthcare system spanning five adult hospitals, we analysed outcomes of patients based on race and ethnicity. Methods This was a retrospective cohort analysis of patients 18 years or older admitted to five hospitals in the mid-Atlantic area between 4 March 2020 and 27 May 2022 with confirmed COVID-19. Participants were divided into four groups based on their race/ethnicity: non-Hispanic black, non-Hispanic white, Latinx and other. Propensity score weighted generalised linear models were used to assess the association between race/ethnicity and the primary outcome of in-hospital mortality. Results Of the 9651 participants in the cohort, more than half were aged 18–64 years old (56%) and 51% of the cohort were females. Non-Hispanic white patients had higher mortality (p<0.001) and longer hospital length-of-stay (p<0.001) than Latinx and non-Hispanic black patients. Discussion In this large multihospital cohort of patients admitted with COVID-19, non-Hispanic black and Hispanic patients did not have worse outcomes than white patients. Such findings likely reflect how the complex range of factors that resulted in a life-threatening and disproportionate impact of incidence on certain vulnerable populations by COVID-19 in the community was offset through admission at well-resourced hospitals and healthcare systems. However, there continues to remain a need for efforts to address the significant pre-existing race and ethnicity inequities highlighted by the COVID-19 pandemic to be better prepared for future public health emergencies. Data are available on reasonable request.
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在大西洋中部的一个医疗保健系统中,因 COVID-19 而住院的少数民族患者的死亡率没有种族和民族差异
导言:在美国,与非西班牙裔白人社区相比,少数民族社区(种族和族裔)因 COVID-19 而受到的伤害更大。在一个医疗系统中,有五家成人医院收治了大量因 COVID-19 而住院的患者,我们根据种族和民族对患者的治疗效果进行了分析。方法 这是一项回顾性队列分析,对象是 2020 年 3 月 4 日至 2022 年 5 月 27 日期间在大西洋中部地区五家医院住院的 18 岁或以上确诊为 COVID-19 的患者。根据种族/族裔将参与者分为四组:非西班牙裔黑人、非西班牙裔白人、拉丁裔和其他。采用倾向得分加权广义线性模型评估种族/族裔与院内死亡率这一主要结果之间的关系。结果 在队列中的 9651 名参与者中,半数以上年龄在 18-64 岁之间(56%),51% 为女性。与拉丁裔和非西班牙裔黑人患者相比,非西班牙裔白人患者的死亡率更高(p<0.001),住院时间更长(p<0.001)。讨论 在这个大型多医院 COVID-19 住院患者队列中,非西班牙裔黑人和西班牙裔患者的预后并不比白人患者差。这些发现很可能反映出,COVID-19 在社区对某些弱势人群的发病率造成了威胁生命和不成比例的影响,而在资源丰富的医院和医疗保健系统收治的患者则抵消了这些复杂因素的影响。然而,仍有必要努力解决 COVID-19 大流行所凸显的原有种族和族裔不平等问题,以便为未来的公共卫生突发事件做好更好的准备。如有合理要求,可提供相关数据。
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来源期刊
BMJ Open Respiratory Research
BMJ Open Respiratory Research RESPIRATORY SYSTEM-
CiteScore
6.60
自引率
2.40%
发文量
95
审稿时长
12 weeks
期刊介绍: BMJ Open Respiratory Research is a peer-reviewed, open access journal publishing respiratory and critical care medicine. It is the sister journal to Thorax and co-owned by the British Thoracic Society and BMJ. The journal focuses on robustness of methodology and scientific rigour with less emphasis on novelty or perceived impact. BMJ Open Respiratory Research operates a rapid review process, with continuous publication online, ensuring timely, up-to-date research is available worldwide. The journal publishes review articles and all research study types: Basic science including laboratory based experiments and animal models, Pilot studies or proof of concept, Observational studies, Study protocols, Registries, Clinical trials from phase I to multicentre randomised clinical trials, Systematic reviews and meta-analyses.
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