Timely Hemodialysis for Successful Treatment of Acute Salicylate Overdose in a Young Adult Female - A Case Report.

IF 0.8 Q4 UROLOGY & NEPHROLOGY Indian Journal of Nephrology Pub Date : 2024-01-01 Epub Date: 2023-02-21 DOI:10.4103/ijn.ijn_141_22
Amitabh Kulkarni, Pavan Shrivastava, Rajesh Kumar Phulara
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Abstract

Salicylates are often used in clinical practice as antiplatelets as well as analgesics. Its overdose is not uncommon due to its easy availability over the counter. Mortality is high in severe cases when a lethal dose is consumed. Treatment of overdose is difficult due to the non-availability of an antidote. Hemodialysis is an underutilized treatment modality in such cases. We discuss here a case of a young female who presented to us 2.5 h after the consumption of a lethal dose of salicylate with symptoms of only tinnitus. She was successfully treated with two sessions of hemodialysis. Her drug levels on admission were remarkably high, and early hemodialysis was justified in view of high-dose consumption with minimal symptoms.

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及时血液透析成功治疗一名年轻女性急性水杨酸盐过量 - 病例报告。
水杨酸盐在临床上经常被用作抗血小板和镇痛药。由于在柜台上很容易买到,因此过量服用并不少见。如果服用致死剂量,严重病例的死亡率很高。由于没有解毒剂,过量服用后很难治疗。在这种情况下,血液透析是一种未得到充分利用的治疗方式。我们在此讨论一例年轻女性病例,她在服用致命剂量的水杨酸盐 2.5 小时后就诊,仅有耳鸣症状。通过两次血液透析,她得到了成功的治疗。入院时她体内的药物浓度非常高,考虑到她服用了大剂量的水杨酸类药物却症状轻微,因此有理由尽早进行血液透析。
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来源期刊
Indian Journal of Nephrology
Indian Journal of Nephrology UROLOGY & NEPHROLOGY-
CiteScore
1.40
自引率
0.00%
发文量
128
审稿时长
24 weeks
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