Acute liver failure.

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Jaapa-Journal of the American Academy of Physician Assistants Pub Date : 2024-05-01 Epub Date: 2024-04-25 DOI:10.1097/01.JAA.0000000000000001
James Beck, Jasleen K Bolina, Lisa H Boyd
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引用次数: 0

Abstract

Abstract: Acute liver failure, commonly caused by acetaminophen overdose, is associated with numerous systemic complications including cerebral edema, hypotension, acute kidney injury, and infection. Management is primarily supportive, with an emphasis on excellent neurocritical care. Although some antidotes and targeted treatments exist, the only definitive treatment remains orthotopic liver transplant.

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急性肝衰竭
摘要:急性肝衰竭通常由对乙酰氨基酚过量引起,并伴有多种全身并发症,包括脑水肿、低血压、急性肾损伤和感染。治疗以支持性治疗为主,重点是良好的神经重症护理。虽然存在一些解毒剂和靶向治疗方法,但唯一明确的治疗方法仍然是肝移植。
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来源期刊
CiteScore
1.20
自引率
9.10%
发文量
310
期刊介绍: ​​​JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues. Published monthly, JAAPA''s award-winning editorial includes: -Clinical review articles (with AAPA-approved Category I CME in each issue)- Case reports- Clinical departments- Original health services research- Articles on issues of professional interest to PAs
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