{"title":"[Clinical characteristics and follow-up analysis of 63 cases of silicosis complicated with cavity-pulmonary tuberculosis].","authors":"Z P Dong, Q Y Cui, S P Pan, Y X Zhao","doi":"10.3760/cma.j.cn121094-20230329-000103","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective:</b> To investigate the clinical characteristics and prognosis of silicosis complicated with cavity-pulmonary tuberculosis. <b>Methods:</b> The clinical data of 63 patients with silicosis complicated with cavity-pulmonary tuberculosis (group A) and silicosis patients (group B) admitted to Yantaishan Hospital from July 2018 to July 2022 were collected and analyzed. <b>Results:</b> Patients in group A were all male, and the common symptoms were cough, expectoration, chest tightness, shortness of breath, and hemoptysis. CT cavity lesions involving the lung, often occurs in the lung after the tip section, after the back section and basal segment, thick-walled cavity, may be accompanied by satellite lesions, endobronchial spread focal, pneumothorax, pleural effusion, etc. 1225 cases of group B patients haemoptysis of 59 patients, cavity in 3 patients, haemoptysis and/or cavity rate was lower than that in group A, the difference was statistically significant (<i>P</i><0.05) . In group A, CT reexamination 6-24 months after anti-tuberculosis treatment showed that 52 cases (82.5%) had cavity reduction/healing, 8 cases (12.7%) had recurrence, and 3 cases (4.8%) had damaged lung (2 died) . <b>Conclusion:</b> Silicosis patients with hemoptysis and/or CT in cavity should be more vigilant about combined tuberculosis, anti-tuberculosis treatment and/or dynamic CT follow-up helps laboratory diagnosis negative patients.</p>","PeriodicalId":23958,"journal":{"name":"中华劳动卫生职业病杂志","volume":"42 4","pages":"268-270"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华劳动卫生职业病杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.cn121094-20230329-000103","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Objective: To investigate the clinical characteristics and prognosis of silicosis complicated with cavity-pulmonary tuberculosis. Methods: The clinical data of 63 patients with silicosis complicated with cavity-pulmonary tuberculosis (group A) and silicosis patients (group B) admitted to Yantaishan Hospital from July 2018 to July 2022 were collected and analyzed. Results: Patients in group A were all male, and the common symptoms were cough, expectoration, chest tightness, shortness of breath, and hemoptysis. CT cavity lesions involving the lung, often occurs in the lung after the tip section, after the back section and basal segment, thick-walled cavity, may be accompanied by satellite lesions, endobronchial spread focal, pneumothorax, pleural effusion, etc. 1225 cases of group B patients haemoptysis of 59 patients, cavity in 3 patients, haemoptysis and/or cavity rate was lower than that in group A, the difference was statistically significant (P<0.05) . In group A, CT reexamination 6-24 months after anti-tuberculosis treatment showed that 52 cases (82.5%) had cavity reduction/healing, 8 cases (12.7%) had recurrence, and 3 cases (4.8%) had damaged lung (2 died) . Conclusion: Silicosis patients with hemoptysis and/or CT in cavity should be more vigilant about combined tuberculosis, anti-tuberculosis treatment and/or dynamic CT follow-up helps laboratory diagnosis negative patients.
目的研究矽肺并发空洞型肺结核的临床特征和预后。方法收集并分析2018年7月-2022年7月烟台山医院收治的63例矽肺并发空洞型肺结核患者(A组)和矽肺患者(B组)的临床资料。结果A组患者均为男性,常见症状为咳嗽、祛痰、胸闷、气短、咯血等。CT空洞病变累及肺部,常发生于肺后尖段、后背段及基底段,空洞壁厚,可伴有卫星病灶、支气管内播散灶、气胸、胸腔积液等。1225 例 B 组患者中咯血 59 例,空洞 3 例,咯血和/或空洞率低于 A 组,差异有统计学意义(PConclusion:矽肺患者咯血和(或)空洞CT检查应提高对合并肺结核的警惕,抗结核治疗和(或)动态CT随访有助于实验室诊断阴性患者的诊断。