Spontaneous thrombosis with a conservative approach to posterior spinal artery pseudoaneurysm management: A case series.

IF 1.5 4区 医学 Q4 CLINICAL NEUROLOGY Interventional Neuroradiology Pub Date : 2024-05-07 DOI:10.1177/15910199241249779
Yasaman Pirahanchi, Benjamin Atchie, Michael Flynn, Ian Kaminsky
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Abstract

In this study, we address the rarity and management challenges associated with ruptured spinal artery pseudoaneurysms, which comprise < 1% of subarachnoid hemorrhage cases. With our limited understanding of their natural history, the prevailing consensus leans towards surgical clipping, contrasting with the typically benign symptoms of sudden back pain and lower extremity weakness. Despite reported low morbidity and mortality, fatal re-ruptures underscore the need for effective management strategies. In this context, we present the largest case series to date, featuring five patients with spinal subarachnoid hemorrhage from isolated posterior spinal artery pseudoaneurysms. All cases achieved spontaneous thrombosis and resolution through conservative management, challenging the prevailing surgical emphasis. The patients, aged 58-81, exhibited varied symptoms, including back pain, paresthesia, confusion, and seizures, with hypertension as a common comorbidity. The results of these cases lead us to tender a "hybrid" management strategy, combining conservative measures with short-term follow-up angiograms, fostering a paradigm shift and warranting further investigation into individualized patient care within larger clinical cohorts.

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脊柱后动脉假性动脉瘤保守治疗中的自发性血栓形成:病例系列。
在本研究中,我们探讨了与脊髓动脉假性动脉瘤破裂相关的罕见性和治疗难题,这种疾病在蛛网膜下腔出血病例中所占比例小于 1%。由于我们对其自然病史的了解有限,普遍的共识倾向于手术切除,这与突发性背痛和下肢无力的典型良性症状形成了鲜明对比。尽管报告的发病率和死亡率都很低,但致命的再破裂突出表明需要有效的管理策略。在这种情况下,我们展示了迄今为止最大的病例系列,其中包括五名因孤立性脊髓后动脉假性动脉瘤导致脊髓蛛网膜下腔出血的患者。所有病例均自发形成血栓,并通过保守治疗得到缓解,这对目前普遍强调的手术治疗提出了挑战。这些患者的年龄在 58-81 岁之间,表现出不同的症状,包括背痛、麻痹、意识模糊和癫痫发作,高血压是常见的合并症。这些病例的结果使我们提出了一种 "混合 "管理策略,将保守措施与短期随访血管造影相结合,促进了范式的转变,值得在更大的临床队列中对患者的个体化护理进行进一步研究。
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来源期刊
Interventional Neuroradiology
Interventional Neuroradiology CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
3.60
自引率
11.80%
发文量
192
审稿时长
6-12 weeks
期刊介绍: Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...
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