Nicole Unger-Manhart, Martina Morokutti-Kurz, Petra Zieglmayer, Patrick Lemell, Markus Savli, René Zieglmayer, Hanna Dellago, Eva Prieschl-Grassauer
{"title":"Demonstration of a Decongestant Effect of “Coldamaris Akut” Compared to Saline Nasal Spray in Participants Suffering from Seasonal Allergic Rhinitis","authors":"Nicole Unger-Manhart, Martina Morokutti-Kurz, Petra Zieglmayer, Patrick Lemell, Markus Savli, René Zieglmayer, Hanna Dellago, Eva Prieschl-Grassauer","doi":"10.1101/2024.05.03.24306805","DOIUrl":null,"url":null,"abstract":"<strong>Purpose</strong> Carrageenan-containing nasal sprays are known to alleviate symptoms of common cold and allergic symptoms by building a barrier against airborne intruders. The objective of this study was to develop a hyperosmolar nasal spray with barrier-forming properties and to demonstrate its decongestant effect in the context of allergic rhinitis.","PeriodicalId":501527,"journal":{"name":"medRxiv - Allergy and Immunology","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Allergy and Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.05.03.24306805","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose Carrageenan-containing nasal sprays are known to alleviate symptoms of common cold and allergic symptoms by building a barrier against airborne intruders. The objective of this study was to develop a hyperosmolar nasal spray with barrier-forming properties and to demonstrate its decongestant effect in the context of allergic rhinitis.