The association between multiple trajectories of macronutrient intake and the risk of new-onset diabetes in Chinese adults

IF 3 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM Journal of Diabetes Pub Date : 2024-05-09 DOI:10.1111/1753-0407.13555
Sizhe Wang, Guo Ruirui, Xiaotong Li, Fengdan Wang, Zibo Wu, Yan Liu, Yibo Dong, Bo Li
{"title":"The association between multiple trajectories of macronutrient intake and the risk of new-onset diabetes in Chinese adults","authors":"Sizhe Wang,&nbsp;Guo Ruirui,&nbsp;Xiaotong Li,&nbsp;Fengdan Wang,&nbsp;Zibo Wu,&nbsp;Yan Liu,&nbsp;Yibo Dong,&nbsp;Bo Li","doi":"10.1111/1753-0407.13555","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>The association between macronutrient intake and diabetes is unclear. We used data from the China Health and Nutrition Survey to explore the association between macronutrient intake trajectories and diabetes risk in this study.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>We included 6755 participants who did not have diabetes at baseline and participated in at least three surveys. The energy supply ratio of carbohydrate, protein, and fat was further calculated from dietary data; different macronutrient trajectories were determined using multitrajectory models; and multiple Cox regression models were used to evaluate the association between these trajectories and diabetes.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>We found three multitrajectories: decreased low carbohydrate-increased moderate protein-increased high fat (DLC-IMP-IHF), decreased high carbohydrate-moderate protein-increased low fat (DHC-MP-ILF), and balanced-macronutrients (BM). Compared to the BM trajectory, DHC-MP-ILF trajectories were significantly associated with increased risk of diabetes (hazard ratio [HR]: 3.228, 95% confidence interval [CI]: 1.571–6.632), whereas no association between DLC-IMP-IHF trajectories and diabetes was found in our study (HR: 0.699, 95% CI: 0.351–1.392).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The downward trend of high carbohydrate and the increasing trend of low fat increased the risk of diabetes in Chinese adults.</p>\n \n <div>\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </div>\n </section>\n </div>","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.13555","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Diabetes","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/1753-0407.13555","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Background

The association between macronutrient intake and diabetes is unclear. We used data from the China Health and Nutrition Survey to explore the association between macronutrient intake trajectories and diabetes risk in this study.

Methods

We included 6755 participants who did not have diabetes at baseline and participated in at least three surveys. The energy supply ratio of carbohydrate, protein, and fat was further calculated from dietary data; different macronutrient trajectories were determined using multitrajectory models; and multiple Cox regression models were used to evaluate the association between these trajectories and diabetes.

Results

We found three multitrajectories: decreased low carbohydrate-increased moderate protein-increased high fat (DLC-IMP-IHF), decreased high carbohydrate-moderate protein-increased low fat (DHC-MP-ILF), and balanced-macronutrients (BM). Compared to the BM trajectory, DHC-MP-ILF trajectories were significantly associated with increased risk of diabetes (hazard ratio [HR]: 3.228, 95% confidence interval [CI]: 1.571–6.632), whereas no association between DLC-IMP-IHF trajectories and diabetes was found in our study (HR: 0.699, 95% CI: 0.351–1.392).

Conclusions

The downward trend of high carbohydrate and the increasing trend of low fat increased the risk of diabetes in Chinese adults.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
中国成年人宏量营养素摄入的多重轨迹与新发糖尿病风险之间的关系。
背景:宏量营养素摄入与糖尿病之间的关系尚不明确。在这项研究中,我们利用中国健康与营养调查的数据,探讨了宏量营养素摄入轨迹与糖尿病风险之间的关系:我们纳入了 6755 名基线时未患糖尿病且至少参加过三次调查的参与者。根据膳食数据进一步计算碳水化合物、蛋白质和脂肪的供能比;使用多轨迹模型确定不同的宏量营养素摄入轨迹;使用多元 Cox 回归模型评估这些轨迹与糖尿病之间的关系:我们发现了三种多营养素轨迹:低碳水化合物减少-中等蛋白质增加-高脂肪增加(DLC-IMP-IHF)、高碳水化合物减少-中等蛋白质增加-低脂肪增加(DHC-MP-ILF)和营养素平衡(BM)。与BM轨迹相比,DHC-MP-ILF轨迹与糖尿病风险增加显著相关(危险比[HR]:3.228,95%置信区间[CI]:1.571-6.632),而在我们的研究中没有发现DLC-IMP-IHF轨迹与糖尿病相关(HR:0.699,95%置信区间:0.351-1.392):结论:高碳水化合物的下降趋势和低脂肪的上升趋势增加了中国成年人患糖尿病的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Diabetes
Journal of Diabetes ENDOCRINOLOGY & METABOLISM-
CiteScore
6.50
自引率
2.20%
发文量
94
审稿时长
>12 weeks
期刊介绍: Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation. The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.
期刊最新文献
β-Cell gene expression stress signatures in types 1 and 2 diabetes. Association of systolic blood pressure variability with cognitive decline in type 2 diabetes: A post hoc analysis of a randomized clinical trial Sarcopenia The relationship between glucose patterns in OGTT and adverse pregnancy outcomes in twin pregnancies Gut microbiota, serum metabolites, and lipids related to blood glucose control and type 1 diabetes
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1