Natural-derived acetophenones: chemistry and pharmacological activities

IF 4.8 3区 化学 Q1 CHEMISTRY, MEDICINAL Natural Products and Bioprospecting Pub Date : 2024-05-10 DOI:10.1007/s13659-024-00447-x
Hamid Ahmadpourmir, Homayoun Attar, Javad Asili, Vahid Soheili, Seyedeh Faezeh Taghizadeh, Abolfazl Shakeri
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Abstract

Acetophenones are naturally occurring phenolic compounds which have found in over 24 plant families and also fungi strains. They are exist in both free or glycosides form in nature. The biological activities of these compounds have been assayed and reported including cytotoxicity, antimicrobial, antimalarial, antioxidant and antityrosinase activities. Herein, we review the chemistry and biological activity of natural acetophenone derivatives that have been isolated and identified until January 2024. Taken together, it was reported 252 acetophenone derivatives in which the genera Melicope (69) and Acronychia (44) were the principal species as producers of acetophenones.

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天然萃取的苯乙酮:化学和药理活性。
乙酰苯酮类化合物是天然存在的酚类化合物,在超过 24 个植物科和真菌菌株中都有发现。它们在自然界中以游离或苷的形式存在。这些化合物的生物活性已得到检测和报告,包括细胞毒性、抗菌、抗疟、抗氧化和抗酪氨酸酶活性。在此,我们回顾了截至 2024 年 1 月已分离和鉴定的天然苯乙酮衍生物的化学性质和生物活性。总计报告了 252 种苯乙酮衍生物,其中 Melicope 属(69 种)和 Acronychia 属(44 种)是产生苯乙酮的主要物种。
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来源期刊
Natural Products and Bioprospecting
Natural Products and Bioprospecting CHEMISTRY, MEDICINAL-
CiteScore
8.30
自引率
2.10%
发文量
39
审稿时长
13 weeks
期刊介绍: Natural Products and Bioprospecting serves as an international forum for essential research on natural products and focuses on, but is not limited to, the following aspects: Natural products: isolation and structure elucidation Natural products: synthesis Biological evaluation of biologically active natural products Bioorganic and medicinal chemistry Biosynthesis and microbiological transformation Fermentation and plant tissue cultures Bioprospecting of natural products from natural resources All research articles published in this journal have undergone rigorous peer review. In addition to original research articles, Natural Products and Bioprospecting publishes reviews and short communications, aiming to rapidly disseminate the research results of timely interest, and comprehensive reviews of emerging topics in all the areas of natural products. It is also an open access journal, which provides free access to its articles to anyone, anywhere.
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