[Severe gastroparesia associated with the use of GLP-1 receptor agonists for weight loss].

Siomara Aransuzú Chávez-Sánchez, Hugo Guillermo Cedrón-Cheng
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引用次数: 0

Abstract

Initially developed as medications for diabetes mellitus, GLP-1 agonists have gained much popularity in the treatment of obesity and weight loss. The present case describes a 69-year-old woman with a history of peptic ulcer and use of NSAIDs, who presented with abdominal pain and oral intolerance refractory to conventional management, for which an upper digestive endoscopy was performed, diagnosing severe gastroparesis. Asking more about the story, revealed surreptitious use of semaglutide. She continued with supportive therapy and the symptoms resolved spontaneously. The present case report aims to warn of the potential risks of the use of GLP-1 analogues in the context of endoscopy with sedation.

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[与使用 GLP-1 受体激动剂减肥有关的严重胃痉挛]。
GLP-1 激动剂最初是作为治疗糖尿病的药物开发的,如今在治疗肥胖症和减肥方面大受欢迎。本病例描述了一位 69 岁的妇女,她有消化性溃疡病史,曾使用非甾体抗炎药,出现腹痛和口服不耐受,常规治疗无效,为此进行了上消化道内窥镜检查,诊断为严重胃瘫。进一步询问得知,她曾偷偷使用过塞马鲁肽。她继续接受支持性治疗,症状自然缓解。本病例报告旨在警示在内镜检查中使用 GLP-1 类似物的潜在风险。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
49
期刊介绍: La REVISTA DE GASTROENTEROLOGíA DEL PERÚ, es la publicación oficial de la Sociedad de Gastroenterología del Perú que publica artículos originales, artículos de revisión, reporte de casos, cartas e información general de la especialidad; dirigido a los profesionales de la salud con especial interés en la gastroenterología. La Revista de Gastroenterología del Perú es una publicación de periodicidad trimestral y tiene como objetivo la publicación de artículos científicos inéditos en el campo de la gastroenterología, proporcionando información actualizada y relevante de la especialidad y áreas afines. La Revista de Gastroenterología del Perú publica artículos en dos idiomas, español e inglés, a texto completo en la versión impresa yelectrónica. Los artículos científicos son sometidos a revisores o árbitros nacionales e internacionales, especialistas que opinan bajo la modalidad de doble ciego y de manera anónima sobre la calidad y validez de los mismos. El número de revisores depende del tipo de artículo, dos revisores como mínimo para artículos originales y uno como mínimo para otros tipos de artículos.
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