A Comparison of Hidradenitis Suppurativa Characteristics Among Israeli Arabs and Jews: Analysis of Two Cohorts.

IF 1.8 4区医学 Q2 MEDICINE, GENERAL & INTERNAL Israel Medical Association Journal Pub Date : 2024-05-01

Jen Barak Levitt, Shira Barmatz, Shira Fisch-Gilad, Yossef H Taieb, Adam Dalal, Khashayar Afshari, Nazgol Haddadi, Dana Tzur Bitan, Arnon Dov Cohen, Daniel Mimouni, Emmilia Hodak, Shany Sherman

{"title":"A Comparison of Hidradenitis Suppurativa Characteristics Among Israeli Arabs and Jews: Analysis of Two Cohorts.","authors":"Jen Barak Levitt, Shira Barmatz, Shira Fisch-Gilad, Yossef H Taieb, Adam Dalal, Khashayar Afshari, Nazgol Haddadi, Dana Tzur Bitan, Arnon Dov Cohen, Daniel Mimouni, Emmilia Hodak, Shany Sherman","doi":"","DOIUrl":null,"url":null,"abstract":"Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease involving apocrine gland-bearing regions. There is an under-representation of non-Caucasians in epidemiologic studies of HS. The characteristics of HS in Israeli Arabs have not yet been studied.Objectives: To investigate the demographic and clinical profile of HS in the Israeli Arab population.Methods: A retrospective analysis was conducted in two cohorts of patients with HS in Israel. The patients were derived from the database of a large health management organization (n=4191, 639 Arabs; population-based) and a major tertiary medical center (n=372, 49 Arabs). Demographic and clinical data were compared between ethnic groups.Results: The prevalence of HS in Israeli Arabs was found to be 0.5%, fivefold higher than in Jews. Arab patients were younger (35.3 vs. 40.5 years, P < 0.001) and mostly male (52% vs. 35.7%, P < 0.001), with lower rates of co-morbidities, including smoking (40.8% vs. 55.7%, P < 0.001), hyperlipidemia, and depression as well as a higher rate of dissecting cellulitis (10.2% vs. 1.9%, P = 0.008). HS was more severe in Arabs, but of shorter duration, with mainly axillary involvement (79.6% vs. 57.9%, P = 0.004). Treatment with hormones was more common in Jews, and with biologic agents in Arabs.Conclusions: The findings suggest a different phenotype of HS in Arabs, warranting further study.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"26 5","pages":"283-288"},"PeriodicalIF":1.8000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Israel Medical Association Journal","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease involving apocrine gland-bearing regions. There is an under-representation of non-Caucasians in epidemiologic studies of HS. The characteristics of HS in Israeli Arabs have not yet been studied.

Objectives: To investigate the demographic and clinical profile of HS in the Israeli Arab population.

Methods: A retrospective analysis was conducted in two cohorts of patients with HS in Israel. The patients were derived from the database of a large health management organization (n=4191, 639 Arabs; population-based) and a major tertiary medical center (n=372, 49 Arabs). Demographic and clinical data were compared between ethnic groups.

Results: The prevalence of HS in Israeli Arabs was found to be 0.5%, fivefold higher than in Jews. Arab patients were younger (35.3 vs. 40.5 years, P < 0.001) and mostly male (52% vs. 35.7%, P < 0.001), with lower rates of co-morbidities, including smoking (40.8% vs. 55.7%, P < 0.001), hyperlipidemia, and depression as well as a higher rate of dissecting cellulitis (10.2% vs. 1.9%, P = 0.008). HS was more severe in Arabs, but of shorter duration, with mainly axillary involvement (79.6% vs. 57.9%, P = 0.004). Treatment with hormones was more common in Jews, and with biologic agents in Arabs.

Conclusions: The findings suggest a different phenotype of HS in Arabs, warranting further study.

微信好友朋友圈 QQ好友复制链接

本刊更多论文

以色列阿拉伯人和犹太人化脓性扁桃体炎特征的比较：两个群体的分析

背景：化脓性扁平湿疹（HS）是一种慢性炎症性皮肤病，累及分泌腺区域。在 HS 的流行病学研究中，非高加索人的比例偏低。以色列阿拉伯人的 HS 特征尚未得到研究：调查以色列阿拉伯人口中 HS 的人口和临床特征：对以色列两组 HS 患者进行了回顾性分析。这些患者分别来自一家大型健康管理机构的数据库（n=4191，639 名阿拉伯人；以人口为基础）和一家大型三级医疗中心的数据库（n=372，49 名阿拉伯人）。对不同种族群体的人口统计学和临床数据进行了比较：结果：以色列阿拉伯人的 HS 患病率为 0.5%，是犹太人的五倍。阿拉伯患者更年轻（35.3 岁对 40.5 岁，P < 0.001），男性居多（52% 对 35.7%，P < 0.001），合并疾病的比例较低，包括吸烟（40.8% 对 55.7%，P < 0.001）、高脂血症和抑郁症，以及较高的剥脱性蜂窝组织炎发生率（10.2% 对 1.9%，P = 0.008）。阿拉伯人的 HS 更严重，但持续时间更短，主要累及腋窝（79.6% 对 57.9%，P = 0.004）。犹太人更常接受激素治疗，而阿拉伯人则更常接受生物制剂治疗：结论：研究结果表明，阿拉伯人的 HS 具有不同的表型，值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Israel Medical Association Journal 医学-医学：内科

CiteScore

2.20

自引率

12.50%

发文量

审稿时长

3-8 weeks

期刊介绍： The Israel Medical Association Journal (IMAJ), representing medical sciences and medicine in Israel, is published in English by the Israel Medical Association. The Israel Medical Association Journal (IMAJ) was initiated in 1999.

期刊最新文献

The Use and Abuse of Mohs Micrographic Surgery. Two Cases of Foot Drop Following Liver Transplantation. 3 Letters to Editor. Comparison of Surgical Treatment Using Mohs Micrographic Surgery versus Wide Local Excision for the Treatment of Dermatofibrosarcoma Protuberans. Esophageal Lung and VACTERL Association Combined with Dysmorphic Features.