Neuro-orthopaedic check-up and walking in people with multiple sclerosis: toward a more specific assessment to improve rehabilitation results.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-26 eCollection Date: 2024-04-01 DOI:10.12965/jer.2448128.064
Yoshimasa Sagawa, Coline Guilhendou, Thierry Moulin, Antonio Vinicius Soares, Pierre Decavel
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Abstract

The rehabilitation process of people with multiple sclerosis (PwMS) is a challenge, and decision-making requires a thorough assessment to increase the chances of success in rehabilitation planning. The aim of this study was to investigate the importance of the neuroorthopaedic check-Up (NOChU) for gait prognosis. Participated in the study 105 PwMS with different levels of impairment. The NOChU includes measurements of passive range of motion (ROM), muscle strength, and spasticity. Additionally, was carried out the spatial-temporal analysis of the walking, Timed Up and Go test, and 6-min walk test. ROM remained relatively preserved to perform daily life activities except for ankle dorsiflexion. Muscle strength was also relatively preserved. Spasticity affected especially the ankle muscles, clearly the sural triceps. Among the NOChU measurements the catch seemed to have the most impact on walking on its different phases and on other activities. Accurate NOChU measurements play a crucial role in clinical settings, guiding informed decisions in rehabilitation planning. Future research endeavours could focus on exploring the correlations between NOChU deficiencies and the decline in walking capabilities among PwMS, with the goal of proposing personalized treatment strategies that address their specific requirements.

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多发性硬化症患者的神经矫形检查和行走:通过更具体的评估改善康复效果。
多发性硬化症患者(PwMS)的康复过程是一个挑战,决策需要全面的评估,以增加康复计划的成功机会。本研究旨在探讨神经矫形检查(NOChU)对步态预后的重要性。共有 105 名患有不同程度障碍的残疾人参加了这项研究。神经矫形检查包括被动运动范围(ROM)、肌力和痉挛的测量。此外,还进行了步行、定时起立行走测试和 6 分钟步行测试的时空分析。除踝关节外展外,患者的活动度相对保持不变,可以进行日常生活活动。肌肉力量也相对保持不变。痉挛对踝关节肌肉的影响尤为明显,尤其是肱三头肌。在 NOChU 测量中,抓地力似乎对不同阶段的行走和其他活动影响最大。精确的 NOChU 测量在临床中起着至关重要的作用,可指导康复计划的明智决策。未来的研究工作可侧重于探索 NOChU 缺陷与 PwMS 步行能力下降之间的相关性,目的是针对他们的具体要求提出个性化的治疗策略。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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