Unveiling the significance of impurity profiling: A comprehensive exploration of novel analytical techniques for ensuring quality and safety in herbal formulations

Tejasree Thutkur, Raja Shekhar Nunavath, Krishnaveni Nagappan
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Abstract

Herbal Phytoconstituents, also known as traditional medicines are considered to be harmless with no side effects. Herbal medicines have a global market value of 60 billion and have become increasingly popular in Western communities. Recent studies indicate that many herbal formulations in the market today have not been tested for quality and efficacy. The research outcomes suggest that, a proper quality check is necessary with novel analytical techniques to ensure product's safety. Thus, the impurities and their limits in herbal formulations should be examined as per pharmacopeial standards guidelines. The present review article emphasizes the importance of impurity profiling in herbal formulations and its significant role in natural product quality control. This article also suggests utilizing simple, precise and accurate, analytical methods to eliminate impurities, adulteration and combined synthetic chemicals in herbal products. In conclusion, implementing stricter regulations and creating public awareness about natural product safety measures can eradicate these adulterations since herbal formulations are in high demand in the commercial market after COVID-19.

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揭开杂质分析的神秘面纱:全面探索确保中草药制剂质量和安全的新型分析技术
草本植物成分又称传统药物,被认为是无害、无副作用的。草药的全球市场价值高达 600 亿美元,在西方社会越来越受欢迎。最近的研究表明,目前市场上的许多草药配方都没有经过质量和疗效检测。研究结果表明,有必要采用新型分析技术进行适当的质量检测,以确保产品的安全性。因此,应根据药典标准指南对草药配方中的杂质及其限量进行检测。本综述文章强调了草药配方中杂质分析的重要性及其在天然产品质量控制中的重要作用。文章还建议利用简单、精确和准确的分析方法来消除草药产品中的杂质、掺假和合成化学品。总之,实施更严格的法规和提高公众对天然产品安全措施的认识可以杜绝这些掺假行为,因为在 COVID-19 之后,草药配方在商业市场上的需求量很大。
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