Haiyang Wang , Jing Lu , Mingjiang Wu , Yumei Zhang
{"title":"K2CO3-catalyzed highly efficient O and N-acylation under mild conditions","authors":"Haiyang Wang , Jing Lu , Mingjiang Wu , Yumei Zhang","doi":"10.1016/j.tgchem.2024.100041","DOIUrl":null,"url":null,"abstract":"<div><p>An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K<sub>2</sub>CO<sub>3</sub> was proved to be the most efficient catalyst for the acylation. A broad variety of acylated products were achieved within 15 min at room temperature in high yields. In addition, we found that the 3-position of indoles should have a suitable substituent group under this procedure.</p></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"3 ","pages":"Article 100041"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773223124000062/pdfft?md5=3dee0134e624e47cdb0172e74320ed1d&pid=1-s2.0-S2773223124000062-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Green Chem","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2773223124000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K2CO3 was proved to be the most efficient catalyst for the acylation. A broad variety of acylated products were achieved within 15 min at room temperature in high yields. In addition, we found that the 3-position of indoles should have a suitable substituent group under this procedure.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
