Impact of bariatric surgery on circulating irisin levels: a systematic review and meta‑analysis.

IF 2.4 3区 医学 Q2 SURGERY Updates in Surgery Pub Date : 2024-12-01 Epub Date: 2024-05-14 DOI:10.1007/s13304-024-01866-8
Tannaz Jamialahamdi, Elaheh Mirhadi, Wael Almahmeed, Ali H Eid, Khalid Al-Rasadi, Ninh T Nguyen, Kishore M Gadde, Amirhossein Sahebkar
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Abstract

This systematic review and meta-analysis evaluated changes in circulating irisin levels after bariatric surgery. A systematic search was performed across Embase, Scopus, PubMed, and Web of Science for this study. The meta-analysis was conducted using Comprehensive Meta-Analysis (CMA) V4 software. The overall effect size was depicted through a random-effects meta-analysis and the leave-one-out method. The meta-analysis, which included 13 studies with a total of 407 participants, showed a statistically non-significant reduction in circulating irisin levels following bariatric surgery (SMD:  - 0.089, 95% CI  - 0.281, 0.102, 95% PI:  - 0.790, 0.611, p = 0.360; I2:70.56). Our research found no significant change in irisin levels after bariatric surgery. Moreover, these findings were not associated with the type of surgery or the duration of follow-up.

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减肥手术对循环鸢尾素水平的影响:系统回顾和荟萃分析。
本系统综述和荟萃分析评估了减肥手术后循环鸢尾素水平的变化。本研究对 Embase、Scopus、PubMed 和 Web of Science 进行了系统检索。荟萃分析使用 Comprehensive Meta-Analysis (CMA) V4 软件进行。总体效应大小通过随机效应荟萃分析和 "留一剔除 "法进行描述。荟萃分析包括 13 项研究,共有 407 名参与者,结果显示减肥手术后循环鸢尾素水平的下降在统计学上并不显著(SMD:- 0.089,95% CI - 0.281,0.102,95% PI:- 0.790,0.611,P = 0.360;I2:70.56)。我们的研究发现,减肥手术后鸢尾素水平没有明显变化。此外,这些结果与手术类型和随访时间无关。
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来源期刊
Updates in Surgery
Updates in Surgery Medicine-Surgery
CiteScore
4.50
自引率
7.70%
发文量
208
期刊介绍: Updates in Surgery (UPIS) has been founded in 2010 as the official journal of the Italian Society of Surgery. It’s an international, English-language, peer-reviewed journal dedicated to the surgical sciences. Its main goal is to offer a valuable update on the most recent developments of those surgical techniques that are rapidly evolving, forcing the community of surgeons to a rigorous debate and a continuous refinement of standards of care. In this respect position papers on the mostly debated surgical approaches and accreditation criteria have been published and are welcome for the future. Beside its focus on general surgery, the journal draws particular attention to cutting edge topics and emerging surgical fields that are publishing in monothematic issues guest edited by well-known experts. Updates in Surgery has been considering various types of papers: editorials, comprehensive reviews, original studies and technical notes related to specific surgical procedures and techniques on liver, colorectal, gastric, pancreatic, robotic and bariatric surgery.
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