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Current practice in pancreatic stump management during minimally invasive distal pancreatectomy: results of a national survey from the IGOMIPS registry. 微创远端胰腺切除术中胰腺残端管理的当前实践:IGOMIPS登记处的一项全国调查结果。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-13 DOI: 10.1007/s13304-025-02516-3
Luca Ottaviani, Andrea Celotti, Gianluca Baiocchi, Alessandro Zerbi, Ugo Boggi

Background: Minimally invasive distal pancreatectomy (MIDP) has become more common in recent years, offering shorter recovery times and fewer perioperative complications compared to open surgery. However, postoperative pancreatic fistula (POPF) remains a major concern, driving the search for effective stump management strategies to minimize complications and healthcare costs.

Methods: Between February and March 2025, a 25-item Google Forms questionnaire was emailed to the lead surgeons of all 44 IGOMIPS centers. One response per center was requested. The questionnaire covered a wide range of topics, including the preferred surgical platform (laparoscopic vs robotic), types of transection devices (motorized or non-motorized staplers, energy-based tools), use of staple-line reinforcement, pre-firing compression durations, and postoperative drain-management practices. Descriptive analyses were performed and correlated with existing literature.

Results: A total of 36 invited centers, each utilizing minimally invasive surgical techniques for distal pancreatectomy, completed the survey (response rate: 81.8%, 36/44). The adopted surgical platform was robotic in 14 centers (38.9%), laparoscopic in 11 (30.6%) and mixed in 11 (30.6%). Parenchymal transection relied on motorised staplers in 24 centers (66.7%), conventional staplers in 8 (22.2%) and energy-based devices in 2 (5.6%); two centers (5.5%) tailored the device to gland thickness. Pre-firing compression lasted < 1 min in 6 centers (16.7%), 1-3 min in 16 (44.4%) and > 3 min in 6 (16.7%), while 7 centers (19.4%) had no fixed interval. Staple-line reinforcement was never used in 14 centers (38.9%), always used in 6 (16.7%) and applied selectively in the remainder. Routine prophylactic drainage was practised by 32 centers (88.9%); drains were removed < POD 5 in 14 (38.9%).

Conclusion: The marked heterogeneity in stump-management techniques in MIDP highlights the absence of robust, standardized guidelines, reflecting persistent controversies in the literature. Respondents expressed strong interest in future multicenter trials to establish evidence-based protocols, emphasizing that collaborative, large-scale research is crucial for improving patient outcomes and reducing the risk of POPF.

背景:微创远端胰腺切除术(MIDP)近年来变得越来越普遍,与开放手术相比,恢复时间更短,围手术期并发症更少。然而,术后胰瘘(POPF)仍然是一个主要问题,推动寻找有效的残端管理策略,以尽量减少并发症和医疗费用。方法:在 2025年2月至3月期间,通过电子邮件向所有44个IGOMIPS中心的首席外科医生发送了一份25项谷歌表格问卷。每个中心要求一个答复。问卷涵盖了广泛的主题,包括首选手术平台(腹腔镜还是机器人),横断设备类型(电动或非电动订书机,能量工具),钉线加固的使用,预发射压缩持续时间,以及术后引流管理实践。进行描述性分析,并与现有文献相关联。结果:共有36家受邀中心完成了调查(有效率:81.8%,36/44),每家中心均采用微创手术技术进行远端胰腺切除术。14家中心采用机器人手术平台(38.9%),11家中心采用腹腔镜手术平台(30.6%),11家中心采用混合手术平台(30.6%)。实质横断依赖于24个中心(66.7%),8个中心(22.2%),2个中心(5.6%)使用常规吻合器;两个中心(5.5%)根据压盖厚度定制装置。6例(16.7%)患者的预燃压缩时间为3min, 7例(19.4%)患者的预燃压缩时间无固定间隔。14个中心(38.9%)从未使用订书线加固,6个中心(16.7%)一直使用订书线加固,其余中心选择性使用订书线加固。32个中心(88.9%)实施常规预防性引流;结论:MIDP残肢管理技术的显著异质性突出了缺乏健全、标准化的指导方针,反映了文献中持续存在的争议。受访者对未来的多中心试验表达了浓厚的兴趣,以建立基于证据的方案,强调协作性的大规模研究对于改善患者预后和降低POPF风险至关重要。
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引用次数: 0
Preoperative prediction of metastatic body-tail peripancreatic lymph nodes as a guide for surgical decision-making in pancreatic neck ductal adenocarcinoma. 术前预测转移体尾胰周淋巴结对胰颈导管腺癌手术决策的指导作用
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-13 DOI: 10.1007/s13304-025-02479-5
Domenico Tamburrino, Francesca Fermi, Federico De Stefano, Diego Palumbo, Marco Schiavo Lena, Francesco Prato, Antonino Campisi, Nicolò Pecorelli, Francesco De Cobelli, Massimo Falconi
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引用次数: 0
Transcatheter arterial chemoembolization plus ablation therapy versus liver resection for hepatocellular carcinoma with clinically significant portal hypertension by an inverse probability of treatment weighting analysis. 经导管动脉化疗栓塞加消融治疗与肝切除术治疗肝细胞癌伴临床显著门静脉高压症的治疗加权逆概率分析
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-13 DOI: 10.1007/s13304-025-02505-6
Ming-Cheng Guan, Qian Ding, Wei Ouyang, Na Li, Di Sun, Gui-Xia Zhang, Ji Wang, Hong Zhu
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引用次数: 0
Human Factors and Quantitative Data: Diverging Perspectives on ICG use in Emergency Bowel Surgery -  A systematic literature review. 人为因素和定量数据:ICG在急诊肠外科应用的不同观点-系统文献综述。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-12 DOI: 10.1007/s13304-025-02469-7
Ankita Kulkarni, Camy Sheth, Nikhil Pawa

Indocyanine Green (ICG) fluorescence imaging is increasingly used in emergency bowel surgery to assess intestinal perfusion. While literature reports high technical efficacy, intraoperative interpretation remains variable. This systematic review explores how cognitive and systemic human factors influence ICG's perceived effectiveness, compared to reported quantitative outcomes. A systematic search of PubMed and Embase identified 31 original studies from 266 screened articles. Qualitative synthesis was guided by ENTREQ principles. Bias identification followed a thematic approach using cognitive bias categories based on established clinical decision-making frameworks. ICG was reported to influence surgical decision-making in 302 of 308 cases. However, discrepancies between fluorescence findings and clinical actions occurred in 38.3% of cases. Common cognitive patterns included confirmation and anchoring bias, overconfidence in fluorescence interpretation, and reliance on ICG to support pre-established surgical decisions. Systemic limitations included lack of interdisciplinary input, case-report bias, and absence of standardized interpretation protocols. These were analyzed across a full article-by-article bias matrix and summarized by domain and sentiment. ICG is not solely a diagnostic tool, but a cognitive interface shaped by time pressure, decision momentum, and human interpretation. Rather than providing objective certainty, ICG often reinforces existing clinical judgments. Addressing bias-awareness and integrating interdisciplinary frameworks may enhance interpretive consistency and improve patient outcomes. These findings call for greater cognitive standardization in the intraoperative use of ICG during emergency surgery.

吲哚菁绿(ICG)荧光成像越来越多地用于紧急肠手术评估肠道灌注。虽然文献报道了高技术疗效,但术中解释仍然存在变数。与已报道的定量结果相比,本系统综述探讨了认知和系统性人为因素如何影响ICG的感知有效性。对PubMed和Embase的系统搜索从266篇筛选的文章中确定了31篇原创研究。定性综合以ENTREQ原则为指导。偏见识别遵循基于既定临床决策框架的认知偏见类别的主题方法。据报道,ICG在308例中影响了302例的手术决策。然而,在38.3%的病例中,荧光结果与临床行为存在差异。常见的认知模式包括确认和锚定偏差,对荧光解释的过度自信,以及依赖ICG来支持预先确定的手术决策。系统性限制包括缺乏跨学科投入、病例报告偏倚和缺乏标准化的解释方案。这些都是在一个完整的逐篇偏见矩阵中分析的,并按领域和情感进行总结。ICG不仅仅是一个诊断工具,而且是一个由时间压力、决策动力和人类解释形成的认知界面。ICG不是提供客观的确定性,而是经常强化现有的临床判断。解决偏见意识和整合跨学科框架可以提高解释的一致性和改善患者的结果。这些发现呼吁在急诊手术中对术中使用ICG进行更大的认知标准化。
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引用次数: 0
Anticipating surgical complexity in laparoscopic cholecystectomy: a clinical score based on inflammatory markers. 预测腹腔镜胆囊切除术的手术复杂性:基于炎症标志物的临床评分。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-08 DOI: 10.1007/s13304-025-02511-8
Erick Moreno Delgado, Edwin Leopoldo Maldonado García, Jorge Luis Vargas Lugo, Carlos Ignacio Martínez Huerta, Estefanía Méndez Herrera, Daniela Martínez de León León, Ricardo Antonio Martínez Rivera Rivera
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引用次数: 0
The impact of external stimuli on the acquisition of robotic surgery skills: the Im-AcRoSS study. 外部刺激对机器人手术技能获得的影响:Im-AcRoSS研究。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-08 DOI: 10.1007/s13304-025-02508-3
Chiara De Bonis Cristalli, Isabella Tato, Francesca Duro, Luca Properzi, Roberto Cirocchi, Francesco Grignani, Domenico Tebala, Nicola Avenia, Andrea Coratti, Giovanni D Tebala

Introduction: It is not clear if the acquisition of robotic simulation skills can be affected by external factors during the simulation.

Methods: A cohort of medical students performed five times a basic simulation exercise. Performance indexes were collected to build up individual "learning curves". The participants were randomly divided into five groups and Groups 2 to 5 were "disturbed" by classic music, heavy metal, radio podcast, irregular noises, respectively, whereas participants of Group 1 were not distracted.

Results: In the whole series, there was a progressive improvement of all the simulation parameters and the variability among the participants reduced with time. Group 5 do not reach the higher standards of the other four groups.

Conclusions: Our study demonstrated that simulation could standardize the skills of the trainees at the top level despite different starting points. Irregular noises during the training can delay the acquisition of robotic skills.

目前还不清楚机器人仿真技能的获取是否会受到仿真过程中外部因素的影响。方法:一组医科学生进行了五次基本的模拟练习。收集绩效指标,建立个人“学习曲线”。参与者被随机分为五组,第二组到第五组分别被古典音乐、重金属音乐、广播播客、不规则噪音“打扰”,而第一组的参与者则没有分心。结果:在整个系列中,所有模拟参数都有一个渐进的改善,参与者之间的变异性随着时间的推移而减少。第五组没有达到其他四组的较高标准。结论:本研究表明,尽管学员的起点不同,但模拟训练对学员的技能水平具有标准化作用。训练过程中出现的不规则噪声会延迟机器人技能的习得。
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引用次数: 0
Endoluminal radiofrequency ablation versus glue for preventing pancreatic fistula: a preclinical protocol study. 腔内射频消融与胶水预防胰瘘:临床前方案研究。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-08 DOI: 10.1007/s13304-025-02474-w
Gemma Vellalta, Francesca Marcucci, Fernando Burdio, Patricia Sanchez-Velazquez, Benedetto Ielpo

Postoperative pancreatic fistula (POPF) complicates 9.9-28.5% of pancreatic surgeries. This protocol describes a preclinical study in a large animal model comparing endoluminal radiofrequency ablation (ERFA) and glue occlusion of the main pancreatic duct (MPD), both performed four weeks prior to surgery to induce pancreatic atrophy and potentially reduce the risk of POPF. In this randomized study, healthy pigs were allocated to either the ERFA or the glue occlusion groups. The protocol comprises three sequential procedures: (1) MPD occlusion via a hybrid laparoscopic or robotic approach, (2) minimally invasive pancreatic transection at four weeks, and (3) necropsy 15 days post-transection. This study addresses the technical challenges of manipulating pancreatic ducts in large animals and provides a standardized approach for evaluating MPD occlusion techniques. The methodology enables a robust comparison between ERFA and glue occlusion while accounting for anatomical variations between porcine and human models to support future clinical applications.

术后胰瘘(POPF)并发症发生率为9.9% -28.5%。该方案描述了一项大型动物模型的临床前研究,比较了腔内射频消融(ERFA)和主胰管胶闭塞(MPD),这两种方法都是在手术前四周进行的,以诱导胰腺萎缩并潜在地降低POPF的风险。在这项随机研究中,健康猪被分配到ERFA组或胶水闭塞组。该方案包括三个顺序的程序:(1)通过混合腹腔镜或机器人方法封堵MPD,(2)在四周时进行微创胰腺横断,(3)横断后15天进行尸检。本研究解决了大型动物操作胰管的技术挑战,并为评估MPD闭塞技术提供了标准化的方法。该方法能够在ERFA和胶闭塞之间进行强有力的比较,同时考虑猪和人类模型之间的解剖差异,以支持未来的临床应用。
{"title":"Endoluminal radiofrequency ablation versus glue for preventing pancreatic fistula: a preclinical protocol study.","authors":"Gemma Vellalta, Francesca Marcucci, Fernando Burdio, Patricia Sanchez-Velazquez, Benedetto Ielpo","doi":"10.1007/s13304-025-02474-w","DOIUrl":"https://doi.org/10.1007/s13304-025-02474-w","url":null,"abstract":"<p><p>Postoperative pancreatic fistula (POPF) complicates 9.9-28.5% of pancreatic surgeries. This protocol describes a preclinical study in a large animal model comparing endoluminal radiofrequency ablation (ERFA) and glue occlusion of the main pancreatic duct (MPD), both performed four weeks prior to surgery to induce pancreatic atrophy and potentially reduce the risk of POPF. In this randomized study, healthy pigs were allocated to either the ERFA or the glue occlusion groups. The protocol comprises three sequential procedures: (1) MPD occlusion via a hybrid laparoscopic or robotic approach, (2) minimally invasive pancreatic transection at four weeks, and (3) necropsy 15 days post-transection. This study addresses the technical challenges of manipulating pancreatic ducts in large animals and provides a standardized approach for evaluating MPD occlusion techniques. The methodology enables a robust comparison between ERFA and glue occlusion while accounting for anatomical variations between porcine and human models to support future clinical applications.</p>","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microsatellite instability and immunotherapy: redefining the role of surgery in colorectal cancer. 微卫星不稳定性和免疫治疗:重新定义手术在结直肠癌中的作用。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-08 DOI: 10.1007/s13304-025-02499-1
Fabio Carbone, Antonio Avallone, Paolo Delrio

The integration of molecular diagnostics into surgical oncology is redefining the management of colorectal cancer (CRC). Microsatellite instability (MSI) testing and mismatch repair (MMR) analysis have moved from purely prognostic tools to key determinants of therapeutic strategy. In MSI-high (MSI-H) and MMR-deficient (dMMR) tumours, immune checkpoint inhibitors have shown unprecedented pathological response rates, leading to a paradigm shift in non-metastatic CRC. Recently published trials suggest that immunotherapy may alter the timing and extent of resection, while raising new questions about patient selection, surgical planning, and long-term oncological safety. Conversely, microsatellite-stable (MSS) disease remains a therapeutic frontier, with ongoing studies exploring combined immunotherapy regimens. This evolving landscape demands that surgeons develop a deeper understanding of tumour biology and participate actively in translational research. The future of CRC surgery will rely not only on technical excellence but on the ability to integrate molecular knowledge into precise, multidisciplinary treatment algorithms.

分子诊断与外科肿瘤学的整合正在重新定义结直肠癌(CRC)的管理。微卫星不稳定性(MSI)检测和错配修复(MMR)分析已经从纯粹的预后工具转变为治疗策略的关键决定因素。在msi高(MSI-H)和mmr缺陷(dMMR)肿瘤中,免疫检查点抑制剂显示出前所未有的病理反应率,导致非转移性结直肠癌的范式转变。最近发表的试验表明,免疫疗法可能改变切除的时间和范围,同时提出了关于患者选择、手术计划和长期肿瘤安全性的新问题。相反,微卫星稳定(MSS)疾病仍然是一个治疗前沿,正在进行的研究探索联合免疫治疗方案。这种不断发展的环境要求外科医生对肿瘤生物学有更深入的了解,并积极参与转化研究。结直肠癌手术的未来将不仅依赖于卓越的技术,还依赖于将分子知识整合到精确的多学科治疗算法中的能力。
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引用次数: 0
Transanal drainage tube placement in patients with temporary ileostomy after laparoscopic rectal resection for rectal cancer. 经肛门引流管在直肠癌腹腔镜直肠切除术后临时回肠造口患者中的放置。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-08 DOI: 10.1007/s13304-025-02503-8
Nobuaki Hoshino, Koya Hida, Yuichiro Tsukada, Kazutaka Obama, Jun Watanabe, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Motoko Suzuki, Toshihiro Misumi, Takeshi Naitoh, Masahiko Watanabe, Masaaki Ito

Anastomotic leakage is a serious complication after surgery for rectal cancer. The prevention of anastomotic leakage is important, and prevention methods include temporary ileostomy and transanal drainage tubes. In clinical practice, a TDT is often used in combination with a temporary ileostomy. Many studies have compared ileostomy and TDT; however, there are few reports on the additive effects of TDT in patients with temporary ileostomy. We included patients who underwent laparoscopic surgery for rectal cancer (cT1-2/N0/M0) located within 5 cm of the anal verge at 47 specialized centers in Japan between 2014 and 2017. Gastrointestinal anastomosis was performed in the patients, and a temporary ileostomy was created. Eligible patients were matched 1:1 based on propensity scores for the presence or absence of TDT. Postoperative outcomes and complications were compared between TDT and non-TDT groups. Of 299 cases collected, 252 were eligible for inclusion. After propensity score matching, 166 patients (83 per group) were included. In the TDT group, there was a significant delay in urinary catheter removal (4.3 ± 0.3 vs. 3.5 ± 0.3 days, P = 0.028) and prolonged hospital stay (20.2 ± 1.1 vs. 17.5 ± 1.1 days, P = 0.027). However, there were no significant differences in the number of anastomotic leakages (grade I, 1 vs. 1; grade II, 2 vs. 1; and grade III, 2 vs. 2; P = 1.000) or other postoperative complications between the groups. In patients in which a temporary ileostomy is created during lower rectal cancer surgery, the need for TDT is considered insignificant.

吻合口漏是直肠癌术后的严重并发症。预防吻合口瘘十分重要,预防方法包括临时回肠造口术和经肛门引流管。在临床实践中,TDT常与临时回肠造口术联合使用。许多研究比较了回肠造口术和TDT;然而,关于TDT在临时回肠造口患者中的附加效应的报道很少。我们纳入了2014年至2017年期间在日本47个专业中心接受腹腔镜手术治疗肛门边缘5厘米内的直肠癌(cT1-2/N0/M0)的患者。患者行胃肠吻合术,并建立临时回肠造口。符合条件的患者根据是否存在TDT的倾向得分进行1:1匹配。比较TDT组和非TDT组的术后结局和并发症。在收集的299例病例中,252例符合纳入条件。倾向评分匹配后,纳入166例患者(每组83例)。TDT组尿管拔出时间延迟(4.3±0.3天比3.5±0.3天,P = 0.028),住院时间延长(20.2±1.1天比17.5±1.1天,P = 0.027)。然而,两组间吻合口瘘发生率(I级,1 vs 1; II级,2 vs 1; III级,2 vs 2; P = 1.000)及其他术后并发症发生率无显著差异。在低位直肠癌手术中进行临时回肠造口术的患者,TDT的必要性被认为是微不足道的。
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引用次数: 0
Hints and pitfalls for surgical steps of gasless transaxillary endoscopic thyroidectomy: experiences of nearly 300 cases. 近300例经腋窝无气甲状腺内镜切除术的手术步骤提示及注意事项。
IF 2.2 3区 医学 Q2 SURGERY Pub Date : 2026-01-07 DOI: 10.1007/s13304-025-02498-2
Yizhou Sun, Xinyi Zhang, Hongjie Xu, Yunhui Cai, Andong Xu, Guangjun Zhou

Gasless transaxillary endoscopic thyroidectomy (GTET) offers an extracervical approach with cosmetic benefits, yet spatial orientation around critical structures can be challenging for learners. We aimed to standardize and illustrate a stepwise GTET workflow with clearly annotated intraoperative landmarks. This single-center descriptive study presents a unified, stepwise technique for GTET. High-resolution intraoperative images were annotated in-figure (arrows and labels) to identify constant landmarks and "risk zones," including the recurrent laryngeal nerve (RLN; trunk/entry), inferior parathyroid and feeding vessels, Berry ligament, tracheal plane, external branch of the superior laryngeal nerve (EBSLN) corridor, upper-pole dissection plane, and central compartment boundaries. For each step, concise tips and pitfalls are provided to support reproducibility and teaching. An atlas-style, annotated workflow is presented that links exposure, landmark identification, and safe dissection planes. The figures and legends prioritize consistent orientation cues and highlight commonly hazardous areas (e.g., Berry ligament region, RLN entry, inferior parathyroid pedicle), aiming to reduce ambiguity for less-experienced surgeons. This annotated, stepwise description of GTET may facilitate surgical orientation, communication, and training. The framework is intended to be adaptable across learning environments; future prospective studies should evaluate learning curves and clinical outcomes using standardized endpoints.

无气经腋窝内窥镜甲状腺切除术(GTET)提供了一种具有美容效益的宫颈外入路,但关键结构周围的空间定向对学习者来说可能具有挑战性。我们的目的是标准化和说明逐步GTET工作流程,并明确标注术中里程碑。这个单中心的描述性研究提出了一个统一的,逐步技术的GTET。术中高分辨率图像在图中进行了注释(箭头和标签),以识别固定的标志和“危险区域”,包括喉返神经(RLN;主干/入口)、下甲状旁腺和供血血管、Berry韧带、气管平面、喉上神经外支(EBSLN)走廊、上极剥离平面和中央隔室边界。对于每个步骤,提供了简明的提示和陷阱,以支持再现性和教学。提出了一种地图集式的、带注释的工作流程,将暴露、地标识别和安全解剖平面联系起来。图和图例优先考虑一致的方向提示,并突出了常见的危险区域(例如,Berry韧带区域、RLN入口、甲状旁腺下蒂),旨在减少经验不足的外科医生的模糊性。这种有注释的、逐步的GTET描述可能有助于外科指导、交流和培训。该框架旨在适应各种学习环境;未来的前瞻性研究应该使用标准化的终点来评估学习曲线和临床结果。
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