Mapping the social memory network

IF 28.7 1区 医学 Q1 NEUROSCIENCES Nature Reviews Neuroscience Pub Date : 2024-05-15 DOI:10.1038/s41583-024-00826-w
Maria Papatriantafyllou
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绘制社会记忆网络图
社会记忆使动物能够识别熟悉的同类,并决定对生存至关重要的行为。神经解剖学和功能追踪发现,丘脑筋膜旁核(PF)细胞是sTRNPvalb的主要突触后靶点,而顶叶后皮层(PPC)的谷氨酸能神经元是社会记忆相关信号的突触前来源。社会记忆的编码和检索都需要兴奋性PPC→sTRN和抑制性sTRN→PF回路。细胞追踪实验表明,这些回路结合在一起形成了一条单突触连接途径,通过sTRNPvalb神经元释放的GABA对PPC输入信号做出反应,从而抑制PF的活动。
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期刊介绍: Nature Reviews Neuroscience is a multidisciplinary journal that covers various fields within neuroscience, aiming to offer a comprehensive understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience, facilitated by powerful experimental techniques and theoretical approaches, have made enduring neurobiological questions more accessible. Nature Reviews Neuroscience serves as a reliable and accessible resource, addressing the breadth and depth of modern neuroscience. It acts as an authoritative and engaging reference for scientists interested in all aspects of neuroscience.
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