Beyond PI-RADS: Combining MRI PI-RADS and PSMA-PET/CT PRIMARY Score in a Composite (P) Score for More Accurate Diagnosis of Clinically Significant Prostate Cancer.

Louise Emmett, Nathan Papa, Thomas A Hope, Wolfgang Fendler, Jeremie Calais, Irene Burger, Matthias Eiber, Francesco Barbato, Daniel Moon, William Counter, Nikeith John, Alan Xue, Anthony Franklin, James Thompson, Kris Rasiah, Mark Frydenberg, John Yaxley, James Buteau, Shikha Agrawal, Bao Ho, Andrew Nguyen, Victor Liu, Jonathan Lee, Henry Woo, Edward Hsiao, Thomas Sutherland, Elyse Perry, Phillip Stricker, Michael S Hofman, Veeru Kasivisvanathan, Matthew Roberts, Declan Murphy
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Abstract

The PI-RADS score is standard of care for clinically significant prostate cancer (csPCa) diagnosis. The PRIMARY-score (PSMA-PET/CT) also has high diagnostic accuracy for csPCa. This study aimed to develop an easily calculated combined (P) score for csPCa detection (ISUP ≥ 2) incorporating separately read PI-RADS and PRIMARY scores, with external validation.
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超越 PI-RADS:将磁共振成像 PI-RADS 和 PSMA-PET/CT PRIMARY 评分合并为综合 (P) 评分,更准确地诊断有临床症状的前列腺癌。
PI-RADS 评分是诊断有临床意义的前列腺癌(csPCa)的标准。PRIMARY 评分(PSMA-PET/CT)对 csPCa 的诊断准确率也很高。本研究旨在开发一种易于计算的综合 (P) 评分,用于 csPCa 检测(ISUP ≥ 2),将分别读取的 PI-RADS 和 PRIMARY 评分结合起来,并进行外部验证。
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